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P14838 (HXB5_CHICK) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Homeobox protein Hox-B5
Alternative name(s):
Homeobox protein Hox-2.1
Short name=Ghox-2.1
Gene names
Name:HOXB5
Synonyms:GHOX-2.1
OrganismGallus gallus (Chicken) [Reference proteome]
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Protein attributes

Sequence length82 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular location

Nucleus.

Sequence similarities

Belongs to the Antp homeobox family.

Contains 1 homeobox DNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 82›82Homeobox protein Hox-B5
PRO_0000200131

Regions

DNA binding7 – 6660Homeobox

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
P14838 [UniParc].

Last modified April 1, 1990. Version 1.
Checksum: 53F70ACDC9FDEF8F

FASTA829,877
        10         20         30         40         50         60 
DMTGPDGKRA RTAYTRYQTL ELEKEFHFNR YLTRRRRIEI AHALCLSERQ IKIWFQNRRM 

        70         80 
KWKKDNKLKS MSLASAGSAF QP 

« Hide

References

[1]"Expression pattern of homeobox-containing genes during chick embryogenesis."
Wedden S.E., Pang K., Eichele G.
Development 105:639-650(1989) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Tissue: Erythrocyte.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X16846 Genomic DNA. Translation: CAA34743.1.
PIRS08302.
UniGeneGga.22931.

3D structure databases

ProteinModelPortalP14838.
SMRP14838. Positions 8-69.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9031.ENSGALP00000021557.

Proteomic databases

PaxDbP14838.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGNOG305812.
PhylomeDBP14838.

Family and domain databases

Gene3D1.10.10.60. 1 hit.
InterProIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSPR00024. HOMEOBOX.
SMARTSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
PROSITEPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHXB5_CHICK
AccessionPrimary (citable) accession number: P14838
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: April 16, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Vertebrate homeotic Hox proteins

Nomenclature of vertebrate homeotic Hox proteins and list of entries