P14836 (CAPSD_AMCV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Capsid protein

Alternative name(s):
Coat protein
p41

Gene names

ORF Names:

ORF2

Organism

Artichoke mottled crinkle virus (AMCV)

Taxonomic identifier

12142 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA positive-strand viruses, no DNA stage › Tombusviridae › Tombusvirus

Virus host

Cynara scolymus (Artichoke) (Cynara cardunculus var. scolymus) [TaxID: 59895]

Protein attributes

Sequence length	388 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins.
Subunit structure	Homomultimer Potential.
Subcellular location	Virion Potential.
Sequence similarities	Belongs to the icosahedral plant coat protein family.

Ontologies

Keywords
Cellular component	Virion
Ligand	RNA-binding
Molecular function	Capsid protein T=3 icosahedral capsid protein
Gene Ontology (GO)
Cellular_component	T=3 icosahedral viral capsid Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural molecule activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 388	388	Capsid protein		PRO_0000222859
Regions
	Region	1 – 102	102	R domain, interaction with RNA
	Region	56 – 61	6	Involved in encapsidation By similarity
	Region	103 – 263	161	S domain, virion shell
	Region	264 – 388	125	P domain, projecting
Experimental info
	Sequence conflict	17	1	T → M in CAA35821. Ref.1
	Sequence conflict	149	1	A → R in CAA35821. Ref.1
	Sequence conflict	273	1	L → I in CAA35821. Ref.1
	Sequence conflict	280	1	L → I in CAA35821. Ref.1
	Sequence conflict	306 – 307	2	FR → IC in CAA35821. Ref.1
	Sequence conflict	385	1	V → L in CAA35821. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P14836 [UniParc]. Last modified October 5, 2010. Version 2. Checksum: D8636A99AEC60BC0	FASTA	388	41,164
	10 20 30 40 50 60 MAMVKRNNNT GLIPVSTKQL MALGAAAGAS ALQGFVRNNG AAIVGKVVDV GQKVYKAVKK 70 80 90 100 110 120 RGGKKQQQIK HVGGTGGAIM APVAVTRQLT GSKPKFTGKT SGSVTVTHRE YLSQVNMSTG 130 140 150 160 170 180 FQVNGGIVGN LLQLNPLNGT LFSWLPAIAS NFDQYSFNSV LLHYVPLCAT TEVGRVAMYF 190 200 210 220 230 240 DKDSEDPEPA DRVELANYSV LAETAPWAER ALWVPTDRIK RFCDDSSTLD HKLIDLGQLG 250 260 270 280 290 300 VATYGGAGTN AVGDIFISYS VTLYFPQPTN TLLSTRRLDL AGTPVTASGP GYILLTRTPT 310 320 330 340 350 360 VLTMTFRATG TFVISGAYRC LTSTVLGLTG GVNVNSITVV DNVGTSSSFF INCTVSNLPS 370 380 VITFTTTGIT SATIQCNRAT RQNDVSLI

References

[1]	"Nucleotide sequence of the 3'-terminal region of artichoke mottled crinkle tombusvirus RNA." Grieco F., Gallitelli D. Nucleic Acids Res. 18:1300-1300(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA]. Strain: Bari-Dr. Gallitelli isolate.
[2]	"cDNA cloning of artichoke mottled crinkle virus RNA and localization and sequencing of the coat protein gene." Tavazza M., Lucioli A., Ancora G., Benvenuto E. Plant Mol. Biol. 13:685-692(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA]. Strain: Bari-Dr. Gallitelli isolate.
[3]	Tavazza M. Submitted (OCT-1991) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X51456 Genomic RNA. Translation: CAA35821.1. X16060 Genomic RNA. Translation: CAA34196.1. X62493 Genomic RNA. Translation: CAA44357.1.
PIR	VCVGAC. S08428. S24926.
RefSeq	NP_039810.1. NC_001339.1.
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	P14836.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1493940.
Family and domain databases
InterPro	IPR000937. Capsid_prot_S-dom_vir. [Graphical view]
Pfam	PF00729. Viral_coat. 1 hit. [Graphical view]
PRINTS	PR00233. ICOSAHEDRAL.
PROSITE	PS00555. ICOSAH_VIR_COAT_S. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPSD_AMCV

Accession

Primary (citable) accession number: P14836

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1990
Last sequence update:	October 5, 2010
Last modified:	April 3, 2013
This is version 60 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program