Reviewed, UniProtKB/Swiss-Prot P14831 (SODCP_SOLLC)

Names and origin

Protein names

Recommended name:
    Superoxide dismutase [Cu-Zn], chloroplastic
    EC=1.15.1.1

Gene names

Name:

SODCP.2

Organism

Solanum lycopersicum (Tomato) (Lycopersicon esculentum)

Taxonomic identifier

4081 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum › Lycopersicon

Protein attributes

Sequence length	217 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Cofactor	Binds 1 copper ion per subunit By similarity. Binds 1 zinc ion per subunit By similarity.
Subunit structure	Homotetramer By similarity.
Subcellular location	Plastid › chloroplast.
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family.

Ontologies

Keywords
Cellular component	Chloroplast Plastid
Domain	Transit peptide
Ligand	Copper Metal-binding Zinc
Molecular function	Antioxidant Oxidoreductase
PTM	Disulfide bond
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	chloroplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	antioxidant activity Inferred from electronic annotation. Source: UniProtKB-KW copper ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 63	63	Chloroplast
	Chain	64 – 217	154	Superoxide dismutase [Cu-Zn], chloroplastic		PRO_0000032845
Sites
	Metal binding	109	1	Copper; catalytic By similarity
	Metal binding	111	1	Copper; catalytic By similarity
	Metal binding	126	1	Copper; catalytic By similarity
	Metal binding	126	1	Zinc; structural By similarity
	Metal binding	134	1	Zinc; structural By similarity
	Metal binding	143	1	Zinc; structural By similarity
	Metal binding	146	1	Zinc; structural By similarity
	Metal binding	183	1	Copper; catalytic By similarity
Amino acid modifications
	Disulfide bond	120 ↔ 209		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P14831-1 [UniParc]. Last modified April 1, 1990. Version 1. Checksum: 3FC14252760CF2B0	FASTA	217	22,228
	10 20 30 40 50 60 MAAHSIFTTT STTNSFLYPI SSSSSSPNIN SSFLGVSLNV NAKFGQSLTL YAVTTPKPLT 70 80 90 100 110 120 VFAATKKAVA VLKGNSNVEG VVTLSQDDDG PTTVNVRITG LAPGLHGFHL HEYGDTTNGC 130 140 150 160 170 180 MSTGAHFNPN KLTHGAPGDE IRHAGDLGNI VANADGVAEV TLVDNQIPLT GPNSVVGRAL 190 200 210 VVHELEDDLG KGGHELSLTT GNAGGRLACG VVGLTPI

References

[1]	"Isolation of two cDNA clones from tomato containing two different superoxide dismutase sequences." Perl-Treves R., Nacmias B., Aviv D., Zeelon E.P., Galun E. Plant Mol. Biol. 11:609-623(1988) [Agricola: IND92000006] Cited for: NUCLEOTIDE SEQUENCE. Strain: cv. Sherry. Tissue: Leaf.
[2]	"The tomato gene for the chloroplastic Cu,Zn superoxide dismutase: regulation of expression imposed in transgenic tobacco plants by a short promoter." Kardish N., Magal N., Aviv D., Galun E. Plant Mol. Biol. 25:887-897(1994) [PubMed: 8075404] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	M37151 mRNA. Translation: AAA34195.1. X14041 mRNA. Translation: CAA32200.1. X77175 Genomic DNA. No translation available. X77176 Genomic DNA. No translation available.
PIR	S48021.
UniGene	Les.167
3D structure databases
HSSP	HSSP built from PDB template 1SRD based on UniProtKB P07505.
SMR	P14831. Positions 64-217.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.15.1.1. 281054.
Family and domain databases
InterPro	IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn. [Graphical view]
Gene3D	G3DSA:2.60.40.200. SOD_Cu_Zn. 1 hit.
PANTHER	PTHR10003. SOD_Cu_Zn. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
PRINTS	PR00068. CUZNDISMTASE.
ProDom	PD000469. SOD_CU_ZN. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00087. SOD_CU_ZN_1. 1 hit. PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SODCP_SOLLC

Accession

Primary (citable) accession number: P14831

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1990
Last sequence update:	April 1, 1990
Last modified:	June 16, 2009
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)