Reviewed, UniProtKB/Swiss-Prot P14830 (SODC1_SOLLC)

Names and origin

Protein names

Recommended name:
    Superoxide dismutase [Cu-Zn] 1
    EC=1.15.1.1

Gene names

Name:

SODCC.1

Organism

Solanum lycopersicum (Tomato) (Lycopersicon esculentum)

Taxonomic identifier

4081 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum › Lycopersicon

Protein attributes

Sequence length	152 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Cofactor	Binds 1 copper ion per subunit By similarity. Binds 1 zinc ion per subunit By similarity.
Subunit structure	Homodimer.
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Copper Metal-binding Zinc
Molecular function	Antioxidant Oxidoreductase
PTM	Disulfide bond
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	antioxidant activity Inferred from electronic annotation. Source: UniProtKB-KW copper ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 152	151	Superoxide dismutase [Cu-Zn] 1		PRO_0000164139
Sites
	Metal binding	45	1	Copper; catalytic By similarity
	Metal binding	47	1	Copper; catalytic By similarity
	Metal binding	62	1	Copper; catalytic By similarity
	Metal binding	62	1	Zinc; structural By similarity
	Metal binding	70	1	Zinc; structural By similarity
	Metal binding	79	1	Zinc; structural By similarity
	Metal binding	82	1	Zinc; structural By similarity
	Metal binding	119	1	Copper; catalytic By similarity
Amino acid modifications
	Disulfide bond	56 ↔ 145		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P14830-1 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 2368B30BF296168A	FASTA	152	15,303
	10 20 30 40 50 60 MVKAVAVLNS SEGVSGTYLF TQVGVAPTTV NGNISGLKPG LHGFHVHALG DTTNGCMSTG 70 80 90 100 110 120 PHYNPAGKEH GAPEDEVRHA GDLGNITVGE DGTASFTITD KQIPLTGPQS IIGRAVVVHA 130 140 150 DPDDLGKGGH ELSKSTGNAG GRIACGIIGL QG

References

[1]	"Isolation of two cDNA clones from tomato containing two different superoxide dismutase sequences." Perl-Treves R., Nacmias B., Aviv D., Zeelon E.P., Galun E. Plant Mol. Biol. 11:609-623(1988) [Agricola: IND92000006] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Sherry. Tissue: Leaf.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M37150 mRNA. Translation: AAA34194.1. X14040 mRNA. Translation: CAA32199.1.
PIR	S08350.
UniGene	Les.10666
3D structure databases
SMR	P14830. Positions 1-152.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.15.1.1. 281054.
Family and domain databases
InterPro	IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn. [Graphical view]
PANTHER	PTHR10003. SOD_Cu_Zn. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
PRINTS	PR00068. CUZNDISMTASE.
PROSITE	PS00087. SOD_CU_ZN_1. 1 hit. PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SODC1_SOLLC

Accession

Primary (citable) accession number: P14830

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1990
Last sequence update:	January 23, 2007
Last modified:	January 19, 2010
This is version 78 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)