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P14822

- GLB2B_ANAIN

UniProt

P14822 - GLB2B_ANAIN

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Protein

Globin-2 B chain

Gene
N/A
Organism
Anadara inaequivalvis (Inequivalve ark) (Scapharca inaequivalvis)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi103 – 1031Iron (heme proximal ligand)

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. oxygen binding Source: InterPro
  4. oxygen transporter activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Oxygen transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Globin-2 B chain
Alternative name(s):
Globin II B chain
HBII-B
OrganismiAnadara inaequivalvis (Inequivalve ark) (Scapharca inaequivalvis)
Taxonomic identifieri6561 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaArcoidaArcoideaArcidaeScapharca

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 151151Globin-2 B chainPRO_0000052489Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylserineCurated

Keywords - PTMi

Acetylation

Interactioni

Subunit structurei

Heterotetramer of two alpha chains and two beta chains.1 Publication

Structurei

Secondary structure

1
151
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi3 – 119
Helixi14 – 2714
Turni28 – 303
Helixi31 – 4515
Helixi49 – 524
Helixi53 – 564
Helixi62 – 643
Helixi66 – 8419
Turni85 – 873
Helixi89 – 10416
Turni105 – 1073
Helixi110 – 1134
Helixi114 – 1163
Helixi117 – 12812
Helixi129 – 1313
Helixi134 – 14916

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4HRRX-ray1.25B/D/F/H3-149[»]
4HRTX-ray1.46B/D/F/H3-149[»]
ProteinModelPortaliP14822.
SMRiP14822. Positions 2-151.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP14822.

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin_dom.
[Graphical view]
PfamiPF00042. Globin. 1 hit.
[Graphical view]
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P14822-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
SKVAELANAV VSNADQKDLL RMSWGVLSVD MEGTGLMLMA NLFKTSPSAK
60 70 80 90 100
GKFARLGDVS AGKDNSKLRG HSITLMYALQ NFVDALDDVE RLKCVVEKFA
110 120 130 140 150
VNHINRQISA DEFGEIVGPL RQTLKARMGN YFDEDTVSAW ASLVAVVQAS

L
Length:151
Mass (Da):16,436
Last modified:April 1, 1990 - v1
Checksum:i2F246A7F5A173EC0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X98565 Genomic DNA. Translation: CAA67175.1.
PIRiS09068.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X98565 Genomic DNA. Translation: CAA67175.1 .
PIRi S09068.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4HRR X-ray 1.25 B/D/F/H 3-149 [» ]
4HRT X-ray 1.46 B/D/F/H 3-149 [» ]
ProteinModelPortali P14822.
SMRi P14822. Positions 2-151.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P14822.

Family and domain databases

Gene3Di 1.10.490.10. 1 hit.
InterProi IPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin_dom.
[Graphical view ]
Pfami PF00042. Globin. 1 hit.
[Graphical view ]
SUPFAMi SSF46458. SSF46458. 1 hit.
PROSITEi PS01033. GLOBIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Scapharca hemoglobins, type cases of a novel mode of chain assembly and heme-heme communication. Amino acid sequence and subunit interactions of the tetrameric component."
    Petruzzelli R., Boffi A., Barra D., Bossa F., Ascoli F., Chiancone E.
    FEBS Lett. 259:133-136(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.
  2. Gambacurta A.
    Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 42-114.
  3. "The 2.0 A crystal structure of Scapharca tetrameric hemoglobin: cooperative dimers within an allosteric tetramer."
    Royer W.E. Jr., Heard K.S., Harrington D.J., Chiancone E.
    J. Mol. Biol. 253:168-186(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) IN COMPLEX WITH HEME, SUBUNIT.

Entry informationi

Entry nameiGLB2B_ANAIN
AccessioniPrimary (citable) accession number: P14822
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: October 1, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3