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P14822

- GLB2B_ANAIN

UniProt

P14822 - GLB2B_ANAIN

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Protein
Globin-2 B chain
Gene
N/A
Organism
Anadara inaequivalvis (Inequivalve ark) (Scapharca inaequivalvis)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi103 – 1031Iron (heme proximal ligand)

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. oxygen binding Source: InterPro
  4. oxygen transporter activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Oxygen transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Globin-2 B chain
Alternative name(s):
Globin II B chain
HBII-B
OrganismiAnadara inaequivalvis (Inequivalve ark) (Scapharca inaequivalvis)
Taxonomic identifieri6561 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaArcoidaArcoideaArcidaeScapharca

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 151151Globin-2 B chain
PRO_0000052489Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylserine Inferred

Keywords - PTMi

Acetylation

Interactioni

Subunit structurei

Heterotetramer of two alpha chains and two beta chains.1 Publication

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi3 – 119
Helixi14 – 2714
Turni28 – 303
Helixi31 – 4515
Helixi49 – 524
Helixi53 – 564
Helixi62 – 643
Helixi66 – 8419
Turni85 – 873
Helixi89 – 10416
Turni105 – 1073
Helixi110 – 1134
Helixi114 – 1163
Helixi117 – 12812
Helixi129 – 1313
Helixi134 – 14916

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4HRRX-ray1.25B/D/F/H3-149[»]
4HRTX-ray1.46B/D/F/H3-149[»]
ProteinModelPortaliP14822.
SMRiP14822. Positions 2-151.

Miscellaneous databases

EvolutionaryTraceiP14822.

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin_dom.
[Graphical view]
PfamiPF00042. Globin. 1 hit.
[Graphical view]
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P14822-1 [UniParc]FASTAAdd to Basket

« Hide

SKVAELANAV VSNADQKDLL RMSWGVLSVD MEGTGLMLMA NLFKTSPSAK    50
GKFARLGDVS AGKDNSKLRG HSITLMYALQ NFVDALDDVE RLKCVVEKFA 100
VNHINRQISA DEFGEIVGPL RQTLKARMGN YFDEDTVSAW ASLVAVVQAS 150
L 151
Length:151
Mass (Da):16,436
Last modified:April 1, 1990 - v1
Checksum:i2F246A7F5A173EC0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X98565 Genomic DNA. Translation: CAA67175.1.
PIRiS09068.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X98565 Genomic DNA. Translation: CAA67175.1 .
PIRi S09068.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4HRR X-ray 1.25 B/D/F/H 3-149 [» ]
4HRT X-ray 1.46 B/D/F/H 3-149 [» ]
ProteinModelPortali P14822.
SMRi P14822. Positions 2-151.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P14822.

Family and domain databases

Gene3Di 1.10.490.10. 1 hit.
InterProi IPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin_dom.
[Graphical view ]
Pfami PF00042. Globin. 1 hit.
[Graphical view ]
SUPFAMi SSF46458. SSF46458. 1 hit.
PROSITEi PS01033. GLOBIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Scapharca hemoglobins, type cases of a novel mode of chain assembly and heme-heme communication. Amino acid sequence and subunit interactions of the tetrameric component."
    Petruzzelli R., Boffi A., Barra D., Bossa F., Ascoli F., Chiancone E.
    FEBS Lett. 259:133-136(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.
  2. Gambacurta A.
    Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 42-114.
  3. "The 2.0 A crystal structure of Scapharca tetrameric hemoglobin: cooperative dimers within an allosteric tetramer."
    Royer W.E. Jr., Heard K.S., Harrington D.J., Chiancone E.
    J. Mol. Biol. 253:168-186(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) IN COMPLEX WITH HEME, SUBUNIT.

Entry informationi

Entry nameiGLB2B_ANAIN
AccessioniPrimary (citable) accession number: P14822
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: July 9, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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