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Protein

Globin-2 A chain

Gene
N/A
Organism
Anadara inaequivalvis (Inequivalve ark) (Scapharca inaequivalvis)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi102Iron (heme proximal ligand)1

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Oxygen transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Globin-2 A chain
Alternative name(s):
Globin II A chain
HBII-A
OrganismiAnadara inaequivalvis (Inequivalve ark) (Scapharca inaequivalvis)
Taxonomic identifieri6561 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaArcoidaArcoideaArcidaeScapharca

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00000524882 – 150Globin-2 A chainAdd BLAST149

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2Blocked amino end (Val)1 Publication1

Interactioni

Subunit structurei

Heterotetramer of two alpha chains and two beta chains.1 Publication

Structurei

Secondary structure

1150
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi3 – 10Combined sources8
Helixi13 – 26Combined sources14
Helixi27 – 29Combined sources3
Helixi30 – 44Combined sources15
Helixi46 – 51Combined sources6
Beta strandi54 – 56Combined sources3
Helixi58 – 63Combined sources6
Helixi65 – 83Combined sources19
Turni84 – 86Combined sources3
Helixi88 – 103Combined sources16
Turni104 – 106Combined sources3
Helixi109 – 112Combined sources4
Helixi113 – 115Combined sources3
Helixi116 – 127Combined sources12
Helixi128 – 130Combined sources3
Helixi133 – 149Combined sources17

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4HRRX-ray1.25A/C/E/G2-150[»]
4HRTX-ray1.46A/C/E/G5-150[»]
ProteinModelPortaliP14821.
SMRiP14821.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP14821.

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
[Graphical view]
PfamiPF00042. Globin. 1 hit.
[Graphical view]
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P14821-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVADAVAKVC GSEAIKANLR RSWGVLSADI EATGLMLMSN LFTLRPDTKT
60 70 80 90 100
YFTRLGDVQK GKANSKLRGH AITLTYALNN FVDSLDDPSR LKCVVEKFAV
110 120 130 140 150
NHINRKISGD AFGAIVEPMK ETLKARMGNY YSDDVAGAWA ALVGVVQAAL
Length:150
Mass (Da):16,238
Last modified:January 23, 2007 - v2
Checksum:i39B996380CBC0315
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X71386 mRNA. Translation: CAA50509.1.
S83524 Genomic DNA. Translation: AAL96376.1.
X98566 Genomic DNA. Translation: CAA67176.1.
PIRiS39980.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X71386 mRNA. Translation: CAA50509.1.
S83524 Genomic DNA. Translation: AAL96376.1.
X98566 Genomic DNA. Translation: CAA67176.1.
PIRiS39980.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4HRRX-ray1.25A/C/E/G2-150[»]
4HRTX-ray1.46A/C/E/G5-150[»]
ProteinModelPortaliP14821.
SMRiP14821.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP14821.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
[Graphical view]
PfamiPF00042. Globin. 1 hit.
[Graphical view]
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLB2A_ANAIN
AccessioniPrimary (citable) accession number: P14821
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.