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P14721

- DFRA_ANTMA

UniProt

P14721 - DFRA_ANTMA

Protein

Dihydroflavonol-4-reductase

Gene

DFRA

Organism
Antirrhinum majus (Garden snapdragon)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (01 Apr 1990)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH.

    Pathwayi

    GO - Molecular functioni

    1. coenzyme binding Source: InterPro
    2. dihydrokaempferol 4-reductase activity Source: UniProtKB-EC

    GO - Biological processi

    1. anthocyanin-containing compound biosynthetic process Source: UniProtKB-UniPathway
    2. cellular metabolic process Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Flavonoid biosynthesis

    Keywords - Ligandi

    NADP

    Enzyme and pathway databases

    UniPathwayiUPA00009.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Dihydroflavonol-4-reductase (EC:1.1.1.219)
    Short name:
    DFR
    Alternative name(s):
    Dihydrokaempferol 4-reductase
    Gene namesi
    Name:DFRA
    OrganismiAntirrhinum majus (Garden snapdragon)
    Taxonomic identifieri4151 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsLamialesPlantaginaceaeAntirrhineaeAntirrhinum

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 446446Dihydroflavonol-4-reductasePRO_0000215562Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP14721.
    SMRiP14721. Positions 17-340.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR001509. Epimerase_deHydtase.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF01370. Epimerase. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P14721-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSPTSLNTSS ETAPPSSTTV CVTGAAGFIG SWLVMRLLER GYTVRATVRD    50
    PGNMKKVKHL IELPKADTNL TLWKADMTVE GSFDEAIQGC EGVFHLATSM 100
    EFDSVDPENE VIKPTIDGML NIIKSCVQAK TVKKFIFTTS GGTVNVEEHQ 150
    KPVYDETDSS DMDFINSKKM TGWMYFVSKI LAEKAGMEAA KENNIDFISI 200
    IPPLVVGPFI MPTFPPSLIT ALSPITGNEA HYSIIKQCQY VHLDDLCEGH 250
    IFLFEYPKAE GRYICSSHDA TIYDIAKLIT ENWPEYHIPD EFEGIDKDIP 300
    VVSFSSKKMI GMGFIFKYTL EDMVRGAIDT CREKGMLPYS TKNNKGDEKE 350
    PILNSLENNY NIQDKELFPI SEEKHINGQE NALLSNTQDK ELLPTSEEKR 400
    VNGLESALLS KIQDKEVLPT SGVKHAKGQE NALLPDIAND HTDGRI 446
    Length:446
    Mass (Da):49,633
    Last modified:April 1, 1990 - v1
    Checksum:i8BF4352EFBAC88D8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X15536 mRNA. Translation: CAA33543.1.
    M14756 Genomic DNA. Translation: AAA32664.1.
    PIRiS07464.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X15536 mRNA. Translation: CAA33543.1 .
    M14756 Genomic DNA. Translation: AAA32664.1 .
    PIRi S07464.

    3D structure databases

    ProteinModelPortali P14721.
    SMRi P14721. Positions 17-340.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00009 .

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR001509. Epimerase_deHydtase.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF01370. Epimerase. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Flavonoid synthesis in Petunia hybrida: partial characterization of dihydroflavonol-4-reductase genes."
      Beld M., Martin C., Huits H., Stuitje A.R., Gerats A.G.M.
      Plant Mol. Biol. 13:491-502(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. JI:522.
    2. "Transposable elements generate novel spatial patterns of gene expression in Antirrhinum majus."
      Coen E.S., Carpenter R., Martin C.
      Cell 47:285-296(1986) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-51.

    Entry informationi

    Entry nameiDFRA_ANTMA
    AccessioniPrimary (citable) accession number: P14721
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 1, 1990
    Last sequence update: April 1, 1990
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3