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P14720

- DFRA_PETHY

UniProt

P14720 - DFRA_PETHY

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Protein

Dihydroflavonol-4-reductase

Gene

DFRA

Organism
Petunia hybrida (Petunia)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH.

Pathwayi

GO - Molecular functioni

  1. coenzyme binding Source: InterPro
  2. dihydrokaempferol 4-reductase activity Source: UniProtKB-EC

GO - Biological processi

  1. anthocyanin-containing compound biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Flavonoid biosynthesis

Keywords - Ligandi

NADP

Enzyme and pathway databases

UniPathwayiUPA00009.

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydroflavonol-4-reductase (EC:1.1.1.219)
Short name:
DFR
Alternative name(s):
Dihydrokaempferol 4-reductase
Gene namesi
Name:DFRA
Synonyms:AN6
OrganismiPetunia hybrida (Petunia)
Taxonomic identifieri4102 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaePetunioideaePetunia

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 380380Dihydroflavonol-4-reductasePRO_0000215571Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP14720.
SMRiP14720. Positions 17-338.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF01370. Epimerase. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P14720-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASEAVHAPS PPVAVPTVCV TGAAGFIGSW LVMRLLERGY NVHATVRDPE
60 70 80 90 100
NKKKVKHLLE LPKADTNLTL WKADLTVEGS FDEAIQGCQG VFHVATPMDF
110 120 130 140 150
ESKDPENEVI KPTVRGMLSI IESCAKANTV KRLVFTSSAG TLDVQEQQKL
160 170 180 190 200
FYDQTSWSDL DFIYAKKMTG WMYFASKILA EKAAMEEAKK KNIDFISIIP
210 220 230 240 250
PLVVGPFITP TFPPSLITAL SLITGNEAHY CIIKQGQYVH LDDLCEAHIF
260 270 280 290 300
LYEHPKADGR FICSSHHAII YDVAKMVREK WPEYYVPTEF KGIDKDLPVV
310 320 330 340 350
SFSSKKLTDM GFQFKYTLED MYKGAIDTCR QKQLLPFSTR SAEDNGHNRE
360 370 380
AIAISAQNYA SGKENAPVAN HTEMLSNVEV
Length:380
Mass (Da):42,435
Last modified:October 1, 1996 - v2
Checksum:i6D7138AD5126868A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti1 – 1616MASEA…PVAVP → MPLHLRCSA(PubMed:2491667)CuratedAdd
BLAST
Sequence conflicti71 – 711W → L in CAA33544. (PubMed:2491667)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X79723 Genomic DNA. Translation: CAA56160.1.
X15537 mRNA. Translation: CAA33544.1.
PIRiS07463.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X79723 Genomic DNA. Translation: CAA56160.1 .
X15537 mRNA. Translation: CAA33544.1 .
PIRi S07463.

3D structure databases

ProteinModelPortali P14720.
SMRi P14720. Positions 17-338.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00009 .

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF01370. Epimerase. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genetic control of dihydroflavonol 4-reductase gene expression in Petunia hybrida."
    Huits H., Gerats A.G.M., Kreike M.M., Mol J.N., Koes R.E.
    Plant J. 6:295-310(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Violet 30.
    Tissue: Leaf.
  2. "Flavonoid synthesis in Petunia hybrida: partial characterization of dihydroflavonol-4-reductase genes."
    Beld M., Martin C., Huits H., Stuitje A.R., Gerats A.G.M.
    Plant Mol. Biol. 13:491-502(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. R27.

Entry informationi

Entry nameiDFRA_PETHY
AccessioniPrimary (citable) accession number: P14720
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: October 1, 1996
Last modified: October 29, 2014
This is version 68 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3