Phytochrome C - Arabidopsis thaliana (Mouse-ear cress)

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P14714 (PHYC_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 110. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Phytochrome C

Gene names

Name:	PHYC
Ordered Locus Names:	At5g35840
ORF Names:	MIK22.15

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	1111 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc. It also controls the expression of its own gene(s) in a negative feedback fashion.
Subunit structure	Homodimer.
Post-translational modification	Contains one covalently linked phytochromobilin chromophore By similarity.
Sequence similarities	Belongs to the phytochrome family. Contains 1 GAF domain. Contains 1 histidine kinase domain. Contains 1 PAC (PAS-associated C-terminal) domain. Contains 2 PAS (PER-ARNT-SIM) domains.

Ontologies

Keywords
Biological process	Sensory transduction Transcription Transcription regulation
Domain	Repeat
Ligand	Chromophore
Molecular function	Photoreceptor protein Receptor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	peptidyl-histidine phosphorylation Inferred from electronic annotation. Source: InterPro protein-chromophore linkage Inferred from electronic annotation. Source: UniProtKB-KW protein-tetrapyrrole linkage Inferred from electronic annotation. Source: InterPro red, far-red light phototransduction Inferred from electronic annotation. Source: InterPro regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	membrane Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro G-protein coupled photoreceptor activity Inferred from electronic annotation. Source: InterPro protein homodimerization activity Inferred from electronic annotation. Source: InterPro two-component sensor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
PHYB	P14713	5	EBI-624366,EBI-300727
PHYD	P42497	2	EBI-624366,EBI-624382

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 1111

1111

Phytochrome C

PRO_0000171964

Regions

Domain

213 – 393

181

GAF

Domain

604 – 674

PAS 1

Domain

737 – 808

PAS 2

Domain

889 – 1111

223

Histidine kinase

Sites

Binding site

318

Phytochromobilin chromophore (covalent; via 1 link) By similarity

Experimental info

Sequence conflict

C → Y in CAA83549. Ref.2

Sequence conflict

137

E → Q in CAA83549. Ref.2

Sequence conflict

230

G → S in CAA83549. Ref.2

Sequence conflict

446

N → K in CAA83549. Ref.2

Sequence conflict

505

S → T in CAA83549. Ref.2

Sequence conflict

726

T → K in CAA83549. Ref.2

Sequence conflict

735

K → Q in CAA83549. Ref.2

Sequence conflict

754

I → M in CAA83549. Ref.2

Sequence conflict

822

E → K in CAA83549. Ref.2

Sequence conflict

1017 – 1018

LR → WK in CAA83549. Ref.2

Sequences

Sequence

Length

Mass (Da)

Tools

P14714 [UniParc].

Last modified April 1, 1990. Version 1.
Checksum: 58FE4645501135CA
Show »

FASTA

1,111

123,722

        10         20         30         40         50         60 
MSSNTSRSCS TRSRQNSRVS SQVLVDAKLH GNFEESERLF DYSASINLNM PSSSCEIPSS 

        70         80         90        100        110        120 
AVSTYLQKIQ RGMLIQPFGC LIVVDEKNLK VIAFSENTQE MLGLIPHTVP SMEQREALTI 

       130        140        150        160        170        180 
GTDVKSLFLS PGCSALEKAV DFGEISILNP ITLHCRSSSK PFYAILHRIE EGLVIDLEPV 

       190        200        210        220        230        240 
SPDEVPVTAA GALRSYKLAA KSISRLQALP SGNMLLLCDA LVKEVSELTG YDRVMVYKFH 

       250        260        270        280        290        300 
EDGHGEVIAE CCREDMEPYL GLHYSATDIP QASRFLFMRN KVRMICDCSA VPVKVVQDKS 

       310        320        330        340        350        360 
LSQPISLSGS TLRAPHGCHA QYMSNMGSVA SLVMSVTING SDSDEMNRDL QTGRHLWGLV 

       370        380        390        400        410        420 
VCHHASPRFV PFPLRYACEF LTQVFGVQIN KEAESAVLLK EKRILQTQSV LCDMLFRNAP 

       430        440        450        460        470        480 
IGIVTQSPNI MDLVKCDGAA LYYRDNLWSL GVTPTETQIR DLIDWVLKSH GGNTGFTTES 

       490        500        510        520        530        540 
LMESGYPDAS VLGESICGMA AVYISEKDFL FWFRSSTAKQ IKWGGARHDP NDRDGKRMHP 

       550        560        570        580        590        600 
RSSFKAFMEI VRWKSVPWDD MEMDAINSLQ LIIKGSLQEE HSKTVVDVPL VDNRVQKVDE 

       610        620        630        640        650        660 
LCVIVNEMVR LIDTAAVPIF AVDASGVING WNSKAAEVTG LAVEQAIGKP VSDLVEDDSV 

       670        680        690        700        710        720 
ETVKNMLALA LEGSEERGAE IRIRAFGPKR KSSPVELVVN TCCSRDMTNN VLGVCFIGQD 

       730        740        750        760        770        780 
VTGQKTLTEN YSRVKGDYAR IMWSPSTLIP PIFITNENGV CSEWNNAMQK LSGIKREEVV 

       790        800        810        820        830        840 
NKILLGEVFT TDDYGCCLKD HDTLTKLRIG FNAVISGQKN IEKLLFGFYH RDGSFIEALL 

       850        860        870        880        890        900 
SANKRTDIEG KVTGVLCFLQ VPSPELQYAL QVQQISEHAI ACALNKLAYL RHEVKDPEKA 

       910        920        930        940        950        960 
ISFLQDLLHS SGLSEDQKRL LRTSVLCREQ LAKVISDSDI EGIEEGYVEL DCSEFGLQES 

       970        980        990       1000       1010       1020 
LEAVVKQVME LSIERKVQIS CDYPQEVSSM RLYGDNLRLQ QILSETLLSS IRFTPALRGL 

      1030       1040       1050       1060       1070       1080 
CVSFKVIARI EAIGKRMKRV ELEFRIIHPA PGLPEDLVRE MFQPLRKGTS REGLGLHITQ 

      1090       1100       1110 
KLVKLMERGT LRYLRESEMS AFVILTEFPL I

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Novel phytochrome sequences in Arabidopsis thaliana: structure, evolution, and differential expression of a plant regulatory photoreceptor family." Sharrock R.A., Quail P.H. Genes Dev. 3:1745-1757(1989) [PubMed: 2606345] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Columbia.
[2]	"The PHYC gene of Arabidopsis. Absence of the third intron found in PHYA and PHYB." Cowl J.S., Hartley N., Xie D., Whitelam G.C., Murphy G., Harberd N.P. Plant Physiol. 106:813-814(1994) [PubMed: 7991704] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence features of the 1.6 Mb regions covered by twenty physically assigned P1 clones." Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M., Miyajima N., Tabata S. DNA Res. 4:215-230(1997) [PubMed: 9330910] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[4]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X17343 mRNA. Translation: CAA35223.1. Z32538 Genomic DNA. Translation: CAA83549.1. AB005236 Genomic DNA. Translation: BAB09925.1. CP002688 Genomic DNA. Translation: AED94021.1.
IPI	IPI00516887.
PIR	FKMUC. C33473.
RefSeq	NP_198433.1. NM_122975.2.
UniGene	At.97.
3D structure databases
ProteinModelPortal	P14714.
SMR	P14714. Positions 68-575, 607-724.
ModBase	Search...
Protein-protein interaction databases
IntAct	P14714. 5 interactions.
STRING	P14714.
Proteomic databases
PRIDE	P14714.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT5G35840.1; AT5G35840.1; AT5G35840.
GeneID	833570.
GenomeReviews	Gene locus AT5G35840 in contig BA000015_GR.
KEGG	ath:AT5G35840.
NMPDR	fig\|3702.1.peg.25291.
Organism-specific databases
TAIR	At5g35840.
Phylogenomic databases
eggNOG	KOG0519.
HOGENOM	HBG318405.
InParanoid	P14714.
OMA	LVMSVTI.
PhylomeDB	P14714.
ProtClustDB	CLSN2679275.
Gene expression databases
ArrayExpress	P14714.
Genevestigator	P14714.
GermOnline	AT5G35840. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR003594. ATPase-like_ATP-bd. IPR003018. GAF. IPR001610. PAC. IPR000014. PAS. IPR013654. PAS_2. IPR013767. PAS_fold. IPR016132. Phyto_chromo_attachment. IPR013516. Phyto_chromo_BS. IPR001294. Phytochrome. IPR012129. Phytochrome_A-E. IPR013515. Phytochrome_cen-reg. IPR003661. Sig_transdc_His_kin_sub1_dim/P. IPR005467. Sig_transdc_His_kinase_core. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit.
Pfam	PF01590. GAF. 1 hit. PF02518. HATPase_c. 1 hit. PF00989. PAS. 2 hits. PF08446. PAS_2. 1 hit. PF00360. PHY. 1 hit. [Graphical view]
PIRSF	PIRSF000084. Phytochrome. 1 hit.
PRINTS	PR01033. PHYTOCHROME.
SMART	SM00065. GAF. 1 hit. SM00387. HATPase_c. 1 hit. SM00388. HisKA. 1 hit. SM00086. PAC. 1 hit. SM00091. PAS. 2 hits. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit.
TIGRFAMs	TIGR00229. Sensory_box. 2 hits.
PROSITE	PS50109. HIS_KIN. 1 hit. PS50112. PAS. 2 hits. PS00245. PHYTOCHROME_1. 1 hit. PS50046. PHYTOCHROME_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHYC_ARATH

Accession

Primary (citable) accession number: P14714

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1990
Last sequence update:	April 1, 1990
Last modified:	December 14, 2011
This is version 110 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Binary interactions

With

Entry

#Exp.

IntAct

Notes

Sequence annotation (Features)

Molecule processing

Regions

Sites

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry information

Relevant documents