P14620 (ACYP2_ANAPL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase-2
EC=3.6.1.7

Alternative name(s):
Acylphosphatase, muscle type isozyme
Acylphosphate phosphohydrolase 2

Gene names

Name:

ACYP2

Organism

Anas platyrhynchos (Domestic duck) (Anas boschas)

Taxonomic identifier

8839 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Anseriformes › Anatidae › Anas

Protein attributes

Sequence length	103 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Its physiological role is not yet clear.
Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate.
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
PTM	Acetylation
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 103	102	Acylphosphatase-2		PRO_0000158547
Regions
	Domain	13 – 103	91	Acylphosphatase-like
Sites
	Active site	28	1	Potential
	Active site	46	1	Potential
Amino acid modifications
	Modified residue	2	1	N-acetylserine

Sequences

	Sequence		Length	Mass (Da)
	P14620 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 683D9EC280F40EB4	FASTA	103	11,389
	10 20 30 40 50 60 MSTLGKAPGA LKSVDYEVFG RVQGVCFRMY TEEEARKLGV VGWVKNTSQG TVTGQVQGPE 70 80 90 100 DKVNAMKSWL TKVGSPSSRI DRTNFSNEKE ISKLDFSGFS TRY

References

[1]	"Duck skeletal muscle acylphosphatase: primary structure." Stefani M., Modesti A., Camici G., Manao G., Cappugi G., Berti A., Ramponi G. J. Protein Chem. 5:307-321(1986) Cited for: PROTEIN SEQUENCE OF 2-103. Tissue: Skeletal muscle.
+	Additional computationally mapped references.

Cross-references

Sequence databases
PIR	A45675.
3D structure databases
ProteinModelPortal	P14620.
SMR	P14620. Positions 11-103.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG050454.
Family and domain databases
InterPro	IPR020456. Acylphosphatase. IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
PRINTS	PR00112. ACYLPHPHTASE.
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. 1 hit. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP2_ANAPL

Accession

Primary (citable) accession number: P14620

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1990
Last sequence update:	January 23, 2007
Last modified:	May 31, 2011
This is version 58 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program