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Protein

Cytochrome c oxidase subunit 3

Gene

cox3

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:cox3
ORF Names:SPMIT.04
Encoded oniMitochondrion
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Mitochondrion

Organism-specific databases

PomBaseiSPMIT.04. cox3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei19 – 39HelicalSequence analysisAdd BLAST21
Transmembranei44 – 64HelicalSequence analysisAdd BLAST21
Transmembranei87 – 107HelicalSequence analysisAdd BLAST21
Transmembranei135 – 155HelicalSequence analysisAdd BLAST21
Transmembranei170 – 190HelicalSequence analysisAdd BLAST21
Transmembranei205 – 225HelicalSequence analysisAdd BLAST21
Transmembranei247 – 267HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001838511 – 269Cytochrome c oxidase subunit 3Add BLAST269

Proteomic databases

PRIDEiP14575.

Structurei

3D structure databases

ProteinModelPortaliP14575.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiP14575.
OrthoDBiEOG092C4IN0.
PhylomeDBiP14575.

Family and domain databases

CDDicd01665. Cyt_c_Oxidase_III. 1 hit.
Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR033945. Cyt_c_oxase_su3_dom.
IPR000298. Cyt_c_oxidase-like_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P14575-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLSTKFQGH PYHIVSASPW PFFLSVVLFF NCLAATLYLH GYKHSSVFFG
60 70 80 90 100
ISFLGLLATM YLWFRDMSTE ANIHGAHTKA VTKGLKIGFM LFLISETFLF
110 120 130 140 150
ASIFWAFFHS SLSPTFELGA VWPPVGIADK TIDPLEVPLL NTVILLTSGA
160 170 180 190 200
SLTYAHYSLI ARNRENALKG LYMTIALSFL FLGGQAYEYW NAPFTISDSV
210 220 230 240 250
YGASFYFATG LHGIHIIVGT ILLLAATYNI YTYHLTNTHH NGFECGIYYW
260
HFCDVVWLFL YLTIYIWGS
Length:269
Mass (Da):30,408
Last modified:December 15, 1998 - v4
Checksum:iDD1788A4AEDE1775
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X16868 Genomic DNA. Translation: CAA34755.1.
X54421 Genomic DNA. No translation available.
PIRiS10080.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X16868 Genomic DNA. Translation: CAA34755.1.
X54421 Genomic DNA. No translation available.
PIRiS10080.

3D structure databases

ProteinModelPortaliP14575.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP14575.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

PomBaseiSPMIT.04. cox3.

Phylogenomic databases

InParanoidiP14575.
OrthoDBiEOG092C4IN0.
PhylomeDBiP14575.

Miscellaneous databases

PROiP14575.

Family and domain databases

CDDicd01665. Cyt_c_Oxidase_III. 1 hit.
Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR033945. Cyt_c_oxase_su3_dom.
IPR000298. Cyt_c_oxidase-like_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCOX3_SCHPO
AccessioniPrimary (citable) accession number: P14575
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: December 15, 1998
Last modified: November 30, 2016
This is version 104 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.