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P14575 (COX3_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:cox3
ORF Names:SPMIT.04
Encoded onMitochondrion
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 269269Cytochrome c oxidase subunit 3
PRO_0000183851

Regions

Transmembrane19 – 3921Helical; Potential
Transmembrane44 – 6421Helical; Potential
Transmembrane87 – 10721Helical; Potential
Transmembrane135 – 15521Helical; Potential
Transmembrane170 – 19021Helical; Potential
Transmembrane205 – 22521Helical; Potential
Transmembrane247 – 26721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P14575 [UniParc].

Last modified December 15, 1998. Version 4.
Checksum: DD1788A4AEDE1775

FASTA26930,408
        10         20         30         40         50         60 
MNLSTKFQGH PYHIVSASPW PFFLSVVLFF NCLAATLYLH GYKHSSVFFG ISFLGLLATM 

        70         80         90        100        110        120 
YLWFRDMSTE ANIHGAHTKA VTKGLKIGFM LFLISETFLF ASIFWAFFHS SLSPTFELGA 

       130        140        150        160        170        180 
VWPPVGIADK TIDPLEVPLL NTVILLTSGA SLTYAHYSLI ARNRENALKG LYMTIALSFL 

       190        200        210        220        230        240 
FLGGQAYEYW NAPFTISDSV YGASFYFATG LHGIHIIVGT ILLLAATYNI YTYHLTNTHH 

       250        260 
NGFECGIYYW HFCDVVWLFL YLTIYIWGS 

« Hide

References

« Hide 'large scale' references
[1]"Nucleotide sequence of the gene encoding subunit 3 of cytochrome c oxidase (cox3) in the mitochondrial genome of Schizosaccharomyces pombe strain EF1."
Trinkl H., Wolf K.
Nucleic Acids Res. 17:10104-10104(1989) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: EF1.
[2]"The mitochondrial genome of Schizosaccharomyces pombe."
Lang B.F.
(In) O'Brien S.J. (eds.); Genetic Maps (6th edition), pp.3118-3119, Cold Spring Harbor Laboratory Press, New York (1993)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AD7-50.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X16868 Genomic DNA. Translation: CAA34755.1.
X54421 Genomic DNA. No translation available.
PIRS10080.

3D structure databases

ProteinModelPortalP14575.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

OrthoDBEOG7V76HP.
PhylomeDBP14575.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP14575.

Entry information

Entry nameCOX3_SCHPO
AccessionPrimary (citable) accession number: P14575
Entry history
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: December 15, 1998
Last modified: May 14, 2014
This is version 88 of the entry and version 4 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names