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P14574

- COX3_LOCMI

UniProt

P14574 - COX3_LOCMI

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Protein
Cytochrome c oxidase subunit 3
Gene
COIII
Organism
Locusta migratoria (Migratory locust)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COIII
Encoded oniMitochondrion
OrganismiLocusta migratoria (Migratory locust)
Taxonomic identifieri7004 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraOrthopteroideaOrthopteraCaeliferaAcridomorphaAcridoideaAcrididaeOedipodinaeLocusta

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei9 – 2921Helical; Reviewed prediction
Add
BLAST
Transmembranei40 – 6021Helical; Reviewed prediction
Add
BLAST
Transmembranei84 – 10421Helical; Reviewed prediction
Add
BLAST
Transmembranei129 – 14921Helical; Reviewed prediction
Add
BLAST
Transmembranei161 – 18121Helical; Reviewed prediction
Add
BLAST
Transmembranei198 – 21821Helical; Reviewed prediction
Add
BLAST
Transmembranei241 – 26121Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 263263Cytochrome c oxidase subunit 3
PRO_0000183800Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP14574.
SMRiP14574. Positions 5-263.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P14574-1 [UniParc]FASTAAdd to Basket

« Hide

MLTNNNNHPF HMVDYSPWPL TGAIGAMILT SGMTKWFHTF NMNLLMIGMT    50
VIVLTMIQWW RDVVREGTFQ GLHTKLVSKG LRWGMILFIA SEVLFFASFF 100
WAFFNSSLAP TIELGMKWPP MGIQPFNPIQ IPLLNTAILL ASGVTITWAH 150
HSIMECNHSQ ALQGLFFTVM LGFYFTLLQM YEYWEAPFTI ADAVYGSTFF 200
VATGFHGLHV IIGTTFLLTC LIRHMMNQFS SNHHFGFEAA AWYWHFVDVV 250
WLFLYLSIYW WGS 263
Length:263
Mass (Da):30,353
Last modified:January 1, 1990 - v1
Checksum:iC5ED6EDB148B37BD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X13975 Genomic DNA. Translation: CAA32156.1.
X80245 Genomic DNA. Translation: CAA56529.1.
PIRiT11469.
RefSeqiNP_007295.1. NC_001712.1.

Genome annotation databases

GeneIDi807961.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X13975 Genomic DNA. Translation: CAA32156.1 .
X80245 Genomic DNA. Translation: CAA56529.1 .
PIRi T11469.
RefSeqi NP_007295.1. NC_001712.1.

3D structure databases

ProteinModelPortali P14574.
SMRi P14574. Positions 5-263.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 807961.

Organism-specific databases

CTDi 4514.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Different mitochondrial gene orders among insects: exchanged tRNA gene positions in the COII/COIII region between an orthopteran and a dipteran species."
    Haucke H.R., Gellissen G.
    Curr. Genet. 14:471-476(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The sequence, organization, and evolution of the Locusta migratoria mitochondrial genome."
    Flook P.K., Rowell C.H.F., Gellissen G.
    J. Mol. Evol. 41:928-941(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiCOX3_LOCMI
AccessioniPrimary (citable) accession number: P14574
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: September 3, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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