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Protein

Chitinase

Gene

chiA2

Organism
Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei151Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Chitin degradation, Polysaccharide degradation

Protein family/group databases

CAZyiGH18. Glycoside Hydrolase Family 18.

Names & Taxonomyi

Protein namesi
Recommended name:
Chitinase (EC:3.2.1.14)
Gene namesi
Name:chiA2
Ordered Locus Names:SACE_1076
OrganismiSaccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)
Taxonomic identifieri405948 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPseudonocardialesPseudonocardiaceaeSaccharopolyspora
Proteomesi
  • UP000006728 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 351 PublicationAdd BLAST35
ChainiPRO_000007704436 – 326ChitinaseAdd BLAST291

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi80 ↔ 124
Disulfide bondi300 ↔ 307

Keywords - PTMi

Disulfide bond

Interactioni

Protein-protein interaction databases

STRINGi405948.SeryN2_010100017775.

Structurei

3D structure databases

ProteinModelPortaliP14529.
SMRiP14529.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4106UDK. Bacteria.
ENOG410YJS7. LUCA.
HOGENOMiHOG000241521.
OMAiRNNGLAR.
OrthoDBiPOG091H0D4M.

Family and domain databases

InterProiView protein in InterPro
IPR017853. Glycoside_hydrolase_SF.
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P14529-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKLRKNLLA WAGTGVAAAC AVTMTAVPAL STPEPEAAGV VSASPYLYNG
60 70 80 90 100
WGNPPSPTEV MNASGIKNFT LAFILADGTC NPAWDGNRPL DGQDKATIDA
110 120 130 140 150
IRGAGGDVIP SIGGYSGSKL GEVCQDSQSL AGAYQKVIDA YGLKAIDVDI
160 170 180 190 200
EATEFENDAS QTRVLEALKI VKEANPGLRT VVTFPTLVNG PNDVGKRMID
210 220 230 240 250
KAARIGSDVD VWTQMPFNFG GGDMAADTIT STEGLVAHLK SAFGYDDATA
260 270 280 290 300
YAHAGISSMN GKSDTGETVD QAAFQKMADY AGEKGLGRLS FWSVNRDRPC
310 320
DGAPDACGGI DQQPWDFTKI VAGLQS
Length:326
Mass (Da):34,023
Last modified:February 22, 2012 - v2
Checksum:i5A9060DF8D8F79A1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti161Q → E AA sequence (PubMed:2670919).Curated1
Sequence conflicti314Missing AA sequence (PubMed:2670919).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM420293 Genomic DNA. Translation: CAM00408.1.
PIRiJX0076.
RefSeqiWP_009946603.1. NZ_ABFV01000030.1.

Genome annotation databases

EnsemblBacteriaiCAM00408; CAM00408; SACE_1076.
KEGGisen:SACE_1076.

Similar proteinsi

Entry informationi

Entry nameiCHIT_SACEN
AccessioniPrimary (citable) accession number: P14529
Secondary accession number(s): A4F8N3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: February 22, 2012
Last modified: June 7, 2017
This is version 95 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families