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Protein

Pupal cuticle protein

Gene

Pcp

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Component of the cuticle of the pupa of fruit fly.

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Pupal cuticle protein
Gene namesi
Name:Pcp
ORF Names:CG3440
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0003046. Pcp.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cuticle

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_000000639716 – 184Pupal cuticle proteinAdd BLAST169

Proteomic databases

PaxDbiP14484.
PRIDEiP14484.

Expressioni

Developmental stagei

Expressed throughout both the fourth and the fifth larval instars.

Gene expression databases

BgeeiFBgn0003046.
GenevisibleiP14484. DM.

Structurei

3D structure databases

SMRiP14484.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 103Chitin-binding type R&RPROSITE-ProRule annotationAdd BLAST62

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410KC0S. Eukaryota.
ENOG4110MQM. LUCA.
GeneTreeiENSGT00840000130268.
InParanoidiP14484.
OMAiIRTHPYQ.
OrthoDBiEOG091G0KRD.
PhylomeDBiP14484.

Family and domain databases

InterProiView protein in InterPro
IPR031311. CHIT_BIND_RR_consensus.
IPR000618. Insect_cuticle.
PfamiView protein in Pfam
PF00379. Chitin_bind_4. 1 hit.
PRINTSiPR00947. CUTICLE.
PROSITEiView protein in PROSITE
PS00233. CHIT_BIND_RR_1. 1 hit.
PS51155. CHIT_BIND_RR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P14484-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYLLVNFIVA LAVLQVQAGS SYIPDSDRNT RTLQNDLQVE RDGKYRYAYE
60 70 80 90 100
TSNGISASQE GLGGVAVQGG SSYTSPEGEV ISVNYVADEF GYHPVGAHIP
110 120 130 140 150
QVPDYILRSL EYIRTHPYQI KDYYTGELKT VEHDAAAFNV YTRNIQDHTI
160 170 180
PQSRPSTTPK TIYLTHPPTT TSRPLRQRRA LPTH
Length:184
Mass (Da):20,633
Last modified:January 1, 1990 - v1
Checksum:i4493B893F61329C2
GO

Sequence cautioni

The sequence ABX00770 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti4L → LQ in AAA28564 (PubMed:3079672).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J02527 Genomic DNA. Translation: AAA28564.1.
AE014134 Genomic DNA. Translation: AAF52475.1.
BT031148 mRNA. Translation: ABX00770.1. Different initiation.
PIRiB24787. UCFFPM.
RefSeqiNP_476673.1. NM_057325.3.

Genome annotation databases

EnsemblMetazoaiFBtr0079388; FBpp0079016; FBgn0003046.
GeneIDi33985.
KEGGidme:Dmel_CG3440.

Similar proteinsi

Entry informationi

Entry nameiCUPP_DROME
AccessioniPrimary (citable) accession number: P14484
Secondary accession number(s): A8WHK2, Q9VM52
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: August 30, 2017
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase