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P14291

- RED1_YEAST

UniProt

P14291 - RED1_YEAST

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Protein
Protein RED1
Gene
RED1, YLR263W, L8479.6
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Probable constituent of the synaptonemal complex during meiosis. May interact with HOP1. Required for meiosis I chromosome segregation.

GO - Molecular functioni

  1. chromatin DNA binding Source: SGD
  2. protein binding Source: IntAct
  3. structural molecule activity Source: SGD

GO - Biological processi

  1. chromosome segregation Source: InterPro
  2. meiotic recombination checkpoint Source: SGD
  3. positive regulation of catalytic activity Source: SGD
  4. reciprocal meiotic recombination Source: InterPro
  5. sporulation resulting in formation of a cellular spore Source: UniProtKB-KW
  6. synaptonemal complex assembly Source: SGD
Complete GO annotation...

Keywords - Biological processi

Meiosis, Sporulation

Enzyme and pathway databases

BioCyciYEAST:G3O-32363-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RED1
Alternative name(s):
Reductional division protein 1
Gene namesi
Name:RED1
Ordered Locus Names:YLR263W
ORF Names:L8479.6
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XII

Organism-specific databases

CYGDiYLR263w.
SGDiS000004253. RED1.

Subcellular locationi

GO - Cellular componenti

  1. lateral element Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 827827Protein RED1
PRO_0000097234Add
BLAST

Proteomic databases

PaxDbiP14291.

Expressioni

Developmental stagei

Meiosis-specific.

Gene expression databases

GenevestigatoriP14291.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
HOP1P200503EBI-14909,EBI-3768303
SMT3Q123066EBI-14909,EBI-17490

Protein-protein interaction databases

BioGridi31531. 44 interactions.
DIPiDIP-2372N.
IntActiP14291. 4 interactions.
MINTiMINT-495817.
STRINGi4932.YLR263W.

Structurei

3D structure databases

ProteinModelPortaliP14291.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG46915.
KOiK12777.
OMAiMESTTIV.
OrthoDBiEOG7NCVDW.

Family and domain databases

InterProiIPR012491. Rec10_Red1.
[Graphical view]
PfamiPF07964. Red1. 1 hit.
[Graphical view]
PIRSFiPIRSF001747. Rec10_Red1. 1 hit.

Sequencei

Sequence statusi: Complete.

P14291-1 [UniParc]FASTAAdd to Basket

« Hide

MEGLKKKIFG VCLKNDLAQT RNETKGIHYG LMTLETSKQL QEFLHLLVIK    50
REVIQNFELL FHIINVAVKI TDSNLPSDDI WHFILKLRFS SEINIDEDSK 100
VLNYLLETGI AMENPVSWKC LAVISSILSS VPQSKKIITN LIETEHAKKI 150
GQLFDNIQDL QQGNFLVEIL SNCFKKSASN SKKVEKIPQL WQSRSKNKFF 200
FENEFYPFSS KNGSLQTCQF LCNNFMSTLS FTGILRQVSY SGSETLKNLR 250
IFKKKDDENS YFIQCIYNKI YLWLDEKAPL EFERKKIRIT KNLKNKIQIK 300
LRQPFHECVR TTADKTALLF NKTKGFQLEF EDEKLGETFF HNVNNIPKIS 350
EVQNFLVLDY IEEEPENEGE EEEQIGRADE QKEDEEEESL DELSTPMVYP 400
IKSSIPHNHN EKVQLVTPDR SVSIRSDEWD LKSNTEDEEG NVLADLKISS 450
TKETKRQTDY VHIDSEDQSP VVSAQMRKMR RESTKTLEIL RQEFKDKDVQ 500
NKEDQSEQIQ NPFVNTSSLV VGKSCLVNPK EKPNIDQTVV GITELKSNSS 550
IKKRDINILD TIFGQPPSKK QKQFHKKEKK KQQKKLTNFK PIIDVPSQDK 600
RNLRSNAPTK PKSIKVSKLR TDKKVTGEKS SPETAAEKVD DQTVRSNDEQ 650
AMSRATKEKC FPDVNEGKEI TKDDAKVSLE SKKNNETFVD SSVVEKHTPP 700
DKDCNNCNIT DILESTTVID LQSPHGLSAP GQNTFTNKLQ EQIYSSINHF 750
SNELVRKISI INQELNKKIL KELSEKYQKL FSELQDNFQN DTNEMLKFMG 800
EIKDMMNLPE DQLVHAIRTR KFDNNKR 827
Length:827
Mass (Da):95,538
Last modified:January 1, 1990 - v1
Checksum:iCA1A206F9A274C3F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X16183 Genomic DNA. Translation: CAA34306.1.
U17244 Genomic DNA. Translation: AAB67376.1.
BK006945 Genomic DNA. Translation: DAA09576.1.
PIRiJQ0308. COBYD1.
RefSeqiNP_013365.1. NM_001182150.1.

Genome annotation databases

EnsemblFungiiYLR263W; YLR263W; YLR263W.
GeneIDi850968.
KEGGisce:YLR263W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X16183 Genomic DNA. Translation: CAA34306.1 .
U17244 Genomic DNA. Translation: AAB67376.1 .
BK006945 Genomic DNA. Translation: DAA09576.1 .
PIRi JQ0308. COBYD1.
RefSeqi NP_013365.1. NM_001182150.1.

3D structure databases

ProteinModelPortali P14291.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 31531. 44 interactions.
DIPi DIP-2372N.
IntActi P14291. 4 interactions.
MINTi MINT-495817.
STRINGi 4932.YLR263W.

Proteomic databases

PaxDbi P14291.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YLR263W ; YLR263W ; YLR263W .
GeneIDi 850968.
KEGGi sce:YLR263W.

Organism-specific databases

CYGDi YLR263w.
SGDi S000004253. RED1.

Phylogenomic databases

eggNOGi NOG46915.
KOi K12777.
OMAi MESTTIV.
OrthoDBi EOG7NCVDW.

Enzyme and pathway databases

BioCyci YEAST:G3O-32363-MONOMER.

Miscellaneous databases

NextBioi 967460.

Gene expression databases

Genevestigatori P14291.

Family and domain databases

InterProi IPR012491. Rec10_Red1.
[Graphical view ]
Pfami PF07964. Red1. 1 hit.
[Graphical view ]
PIRSFi PIRSF001747. Rec10_Red1. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Expression and DNA sequence of RED1, a gene required for meiosis I chromosome segregation in yeast."
    Thompson E.A., Roeder G.S.
    Mol. Gen. Genet. 218:293-301(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII."
    Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H.
    , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D.
    Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.

Entry informationi

Entry nameiRED1_YEAST
AccessioniPrimary (citable) accession number: P14291
Secondary accession number(s): D6VYR0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: June 11, 2014
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

External Data

Dasty 3

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