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P14291

- RED1_YEAST

UniProt

P14291 - RED1_YEAST

Protein

Protein RED1

Gene

RED1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 118 (11 Jun 2014)
      Sequence version 1 (01 Jan 1990)
      Previous versions | rss
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    Functioni

    Probable constituent of the synaptonemal complex during meiosis. May interact with HOP1. Required for meiosis I chromosome segregation.

    GO - Molecular functioni

    1. chromatin DNA binding Source: SGD
    2. protein binding Source: IntAct
    3. structural molecule activity Source: SGD

    GO - Biological processi

    1. chromosome segregation Source: InterPro
    2. meiotic recombination checkpoint Source: SGD
    3. positive regulation of catalytic activity Source: SGD
    4. reciprocal meiotic recombination Source: InterPro
    5. sporulation resulting in formation of a cellular spore Source: UniProtKB-KW
    6. synaptonemal complex assembly Source: SGD

    Keywords - Biological processi

    Meiosis, Sporulation

    Enzyme and pathway databases

    BioCyciYEAST:G3O-32363-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein RED1
    Alternative name(s):
    Reductional division protein 1
    Gene namesi
    Name:RED1
    Ordered Locus Names:YLR263W
    ORF Names:L8479.6
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XII

    Organism-specific databases

    CYGDiYLR263w.
    SGDiS000004253. RED1.

    Subcellular locationi

    GO - Cellular componenti

    1. lateral element Source: SGD

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 827827Protein RED1PRO_0000097234Add
    BLAST

    Proteomic databases

    PaxDbiP14291.

    Expressioni

    Developmental stagei

    Meiosis-specific.

    Gene expression databases

    GenevestigatoriP14291.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    HOP1P200503EBI-14909,EBI-3768303
    SMT3Q123066EBI-14909,EBI-17490

    Protein-protein interaction databases

    BioGridi31531. 44 interactions.
    DIPiDIP-2372N.
    IntActiP14291. 4 interactions.
    MINTiMINT-495817.
    STRINGi4932.YLR263W.

    Structurei

    3D structure databases

    ProteinModelPortaliP14291.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG46915.
    KOiK12777.
    OMAiMESTTIV.
    OrthoDBiEOG7NCVDW.

    Family and domain databases

    InterProiIPR012491. Rec10_Red1.
    [Graphical view]
    PfamiPF07964. Red1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001747. Rec10_Red1. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P14291-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEGLKKKIFG VCLKNDLAQT RNETKGIHYG LMTLETSKQL QEFLHLLVIK    50
    REVIQNFELL FHIINVAVKI TDSNLPSDDI WHFILKLRFS SEINIDEDSK 100
    VLNYLLETGI AMENPVSWKC LAVISSILSS VPQSKKIITN LIETEHAKKI 150
    GQLFDNIQDL QQGNFLVEIL SNCFKKSASN SKKVEKIPQL WQSRSKNKFF 200
    FENEFYPFSS KNGSLQTCQF LCNNFMSTLS FTGILRQVSY SGSETLKNLR 250
    IFKKKDDENS YFIQCIYNKI YLWLDEKAPL EFERKKIRIT KNLKNKIQIK 300
    LRQPFHECVR TTADKTALLF NKTKGFQLEF EDEKLGETFF HNVNNIPKIS 350
    EVQNFLVLDY IEEEPENEGE EEEQIGRADE QKEDEEEESL DELSTPMVYP 400
    IKSSIPHNHN EKVQLVTPDR SVSIRSDEWD LKSNTEDEEG NVLADLKISS 450
    TKETKRQTDY VHIDSEDQSP VVSAQMRKMR RESTKTLEIL RQEFKDKDVQ 500
    NKEDQSEQIQ NPFVNTSSLV VGKSCLVNPK EKPNIDQTVV GITELKSNSS 550
    IKKRDINILD TIFGQPPSKK QKQFHKKEKK KQQKKLTNFK PIIDVPSQDK 600
    RNLRSNAPTK PKSIKVSKLR TDKKVTGEKS SPETAAEKVD DQTVRSNDEQ 650
    AMSRATKEKC FPDVNEGKEI TKDDAKVSLE SKKNNETFVD SSVVEKHTPP 700
    DKDCNNCNIT DILESTTVID LQSPHGLSAP GQNTFTNKLQ EQIYSSINHF 750
    SNELVRKISI INQELNKKIL KELSEKYQKL FSELQDNFQN DTNEMLKFMG 800
    EIKDMMNLPE DQLVHAIRTR KFDNNKR 827
    Length:827
    Mass (Da):95,538
    Last modified:January 1, 1990 - v1
    Checksum:iCA1A206F9A274C3F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X16183 Genomic DNA. Translation: CAA34306.1.
    U17244 Genomic DNA. Translation: AAB67376.1.
    BK006945 Genomic DNA. Translation: DAA09576.1.
    PIRiJQ0308. COBYD1.
    RefSeqiNP_013365.1. NM_001182150.1.

    Genome annotation databases

    EnsemblFungiiYLR263W; YLR263W; YLR263W.
    GeneIDi850968.
    KEGGisce:YLR263W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X16183 Genomic DNA. Translation: CAA34306.1 .
    U17244 Genomic DNA. Translation: AAB67376.1 .
    BK006945 Genomic DNA. Translation: DAA09576.1 .
    PIRi JQ0308. COBYD1.
    RefSeqi NP_013365.1. NM_001182150.1.

    3D structure databases

    ProteinModelPortali P14291.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 31531. 44 interactions.
    DIPi DIP-2372N.
    IntActi P14291. 4 interactions.
    MINTi MINT-495817.
    STRINGi 4932.YLR263W.

    Proteomic databases

    PaxDbi P14291.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YLR263W ; YLR263W ; YLR263W .
    GeneIDi 850968.
    KEGGi sce:YLR263W.

    Organism-specific databases

    CYGDi YLR263w.
    SGDi S000004253. RED1.

    Phylogenomic databases

    eggNOGi NOG46915.
    KOi K12777.
    OMAi MESTTIV.
    OrthoDBi EOG7NCVDW.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-32363-MONOMER.

    Miscellaneous databases

    NextBioi 967460.

    Gene expression databases

    Genevestigatori P14291.

    Family and domain databases

    InterProi IPR012491. Rec10_Red1.
    [Graphical view ]
    Pfami PF07964. Red1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001747. Rec10_Red1. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Expression and DNA sequence of RED1, a gene required for meiosis I chromosome segregation in yeast."
      Thompson E.A., Roeder G.S.
      Mol. Gen. Genet. 218:293-301(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII."
      Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H.
      , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D.
      Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.

    Entry informationi

    Entry nameiRED1_YEAST
    AccessioniPrimary (citable) accession number: P14291
    Secondary accession number(s): D6VYR0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 1, 1990
    Last sequence update: January 1, 1990
    Last modified: June 11, 2014
    This is version 118 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome XII
      Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

    External Data

    Dasty 3