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Protein

Protein RED1

Gene

RED1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Probable constituent of the synaptonemal complex during meiosis. May interact with HOP1. Required for meiosis I chromosome segregation.

GO - Molecular functioni

  • chromatin DNA binding Source: SGD
  • structural molecule activity Source: SGD

GO - Biological processi

  • meiotic recombination checkpoint Source: SGD
  • positive regulation of catalytic activity Source: SGD
  • reciprocal meiotic recombination Source: InterPro
  • sporulation resulting in formation of a cellular spore Source: UniProtKB-KW
  • synaptonemal complex assembly Source: SGD
Complete GO annotation...

Keywords - Biological processi

Meiosis, Sporulation

Enzyme and pathway databases

BioCyciYEAST:G3O-32363-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RED1
Alternative name(s):
Reductional division protein 1
Gene namesi
Name:RED1
Ordered Locus Names:YLR263W
ORF Names:L8479.6
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XII

Organism-specific databases

EuPathDBiFungiDB:YLR263W.
SGDiS000004253. RED1.

Subcellular locationi

GO - Cellular componenti

  • lateral element Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000972341 – 827Protein RED1Add BLAST827

Proteomic databases

PRIDEiP14291.

PTM databases

iPTMnetiP14291.

Expressioni

Developmental stagei

Meiosis-specific.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
HOP1P200503EBI-14909,EBI-3768303
SMT3Q123066EBI-14909,EBI-17490

Protein-protein interaction databases

BioGridi31531. 48 interactors.
DIPiDIP-2372N.
IntActiP14291. 4 interactors.
MINTiMINT-495817.

Structurei

3D structure databases

ProteinModelPortaliP14291.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

InParanoidiP14291.
KOiK12777.
OMAiVGEIKDM.
OrthoDBiEOG092C3XZM.

Family and domain databases

InterProiIPR012491. Red1/Rec10.
[Graphical view]
PfamiPF07964. Red1. 1 hit.
[Graphical view]
PIRSFiPIRSF001747. Rec10_Red1. 1 hit.

Sequencei

Sequence statusi: Complete.

P14291-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGLKKKIFG VCLKNDLAQT RNETKGIHYG LMTLETSKQL QEFLHLLVIK
60 70 80 90 100
REVIQNFELL FHIINVAVKI TDSNLPSDDI WHFILKLRFS SEINIDEDSK
110 120 130 140 150
VLNYLLETGI AMENPVSWKC LAVISSILSS VPQSKKIITN LIETEHAKKI
160 170 180 190 200
GQLFDNIQDL QQGNFLVEIL SNCFKKSASN SKKVEKIPQL WQSRSKNKFF
210 220 230 240 250
FENEFYPFSS KNGSLQTCQF LCNNFMSTLS FTGILRQVSY SGSETLKNLR
260 270 280 290 300
IFKKKDDENS YFIQCIYNKI YLWLDEKAPL EFERKKIRIT KNLKNKIQIK
310 320 330 340 350
LRQPFHECVR TTADKTALLF NKTKGFQLEF EDEKLGETFF HNVNNIPKIS
360 370 380 390 400
EVQNFLVLDY IEEEPENEGE EEEQIGRADE QKEDEEEESL DELSTPMVYP
410 420 430 440 450
IKSSIPHNHN EKVQLVTPDR SVSIRSDEWD LKSNTEDEEG NVLADLKISS
460 470 480 490 500
TKETKRQTDY VHIDSEDQSP VVSAQMRKMR RESTKTLEIL RQEFKDKDVQ
510 520 530 540 550
NKEDQSEQIQ NPFVNTSSLV VGKSCLVNPK EKPNIDQTVV GITELKSNSS
560 570 580 590 600
IKKRDINILD TIFGQPPSKK QKQFHKKEKK KQQKKLTNFK PIIDVPSQDK
610 620 630 640 650
RNLRSNAPTK PKSIKVSKLR TDKKVTGEKS SPETAAEKVD DQTVRSNDEQ
660 670 680 690 700
AMSRATKEKC FPDVNEGKEI TKDDAKVSLE SKKNNETFVD SSVVEKHTPP
710 720 730 740 750
DKDCNNCNIT DILESTTVID LQSPHGLSAP GQNTFTNKLQ EQIYSSINHF
760 770 780 790 800
SNELVRKISI INQELNKKIL KELSEKYQKL FSELQDNFQN DTNEMLKFMG
810 820
EIKDMMNLPE DQLVHAIRTR KFDNNKR
Length:827
Mass (Da):95,538
Last modified:January 1, 1990 - v1
Checksum:iCA1A206F9A274C3F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X16183 Genomic DNA. Translation: CAA34306.1.
U17244 Genomic DNA. Translation: AAB67376.1.
BK006945 Genomic DNA. Translation: DAA09576.1.
PIRiJQ0308. COBYD1.
RefSeqiNP_013365.1. NM_001182150.1.

Genome annotation databases

EnsemblFungiiYLR263W; YLR263W; YLR263W.
GeneIDi850968.
KEGGisce:YLR263W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X16183 Genomic DNA. Translation: CAA34306.1.
U17244 Genomic DNA. Translation: AAB67376.1.
BK006945 Genomic DNA. Translation: DAA09576.1.
PIRiJQ0308. COBYD1.
RefSeqiNP_013365.1. NM_001182150.1.

3D structure databases

ProteinModelPortaliP14291.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31531. 48 interactors.
DIPiDIP-2372N.
IntActiP14291. 4 interactors.
MINTiMINT-495817.

PTM databases

iPTMnetiP14291.

Proteomic databases

PRIDEiP14291.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYLR263W; YLR263W; YLR263W.
GeneIDi850968.
KEGGisce:YLR263W.

Organism-specific databases

EuPathDBiFungiDB:YLR263W.
SGDiS000004253. RED1.

Phylogenomic databases

InParanoidiP14291.
KOiK12777.
OMAiVGEIKDM.
OrthoDBiEOG092C3XZM.

Enzyme and pathway databases

BioCyciYEAST:G3O-32363-MONOMER.

Miscellaneous databases

PROiP14291.

Family and domain databases

InterProiIPR012491. Red1/Rec10.
[Graphical view]
PfamiPF07964. Red1. 1 hit.
[Graphical view]
PIRSFiPIRSF001747. Rec10_Red1. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRED1_YEAST
AccessioniPrimary (citable) accession number: P14291
Secondary accession number(s): D6VYR0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: November 2, 2016
This is version 135 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.