Reviewed, UniProtKB/Swiss-Prot P14235 (ACT_CANAL)

Names and origin

Protein names

Recommended name:
    Actin

Gene names

Name:

ACT1

Organism

Candida albicans (Yeast)

Taxonomic identifier

5476 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Subcellular location	Cytoplasm › cytoskeleton.
Sequence similarities	Belongs to the actin family.

Ontologies

Keywords
Cellular component	Cytoplasm Cytoskeleton
Ligand	ATP-binding Nucleotide-binding
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW cytoskeleton Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 376	376	Actin		PRO_0000088903

Sequences

	Sequence		Length	Mass (Da)
	P14235-1 [UniParc]. Last modified January 1, 1990. Version 1. Checksum: 45D6937E843A3D98	FASTA	376	41,753
	10 20 30 40 50 60 MDGEEVAALI IDNGSGMCKA GFAGDDAPRA VFPSLVGRPR HQGIMVGMGQ KDSYVGDEAQ 70 80 90 100 110 120 SKRGILTLRY PIEHGIVSNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP MNPKSNREKM 130 140 150 160 170 180 TQIMFETFNV PAFYVSIQAV LSLYSSGRTT GIVLDSGDGV THVVPIYAGF SLPHGILRID 190 200 210 220 230 240 LAGRDLTNHL SKILSERGYS FTTSAEREIV RDIKERLCYV ALDFEQEMQT SSQSSAIEKS 250 260 270 280 290 300 YELPDGQVIT IGNERFRAPE ALFRPADLGL EAAGIDQTTF NSIMKCDMDV RKELYGNIVM 310 320 330 340 350 360 SGGTTMFPGI AERMQKEITA LAPSSMKVKI IAPPERKYSV WIGGSILASL STFQQMWISK 370 QEYDESGPSI VHHKCF

References

[1]	"Sequence of the Candida albicans gene encoding actin." Losberger C., Ernst J.P. Nucleic Acids Res. 17:9488-9488(1989) [PubMed: 2685762] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 10123.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X16377 Genomic DNA. Translation: CAA34413.1.
PIR	S07639.
3D structure databases
SMR	P14235. Positions 5-372.
ModBase	Search...
Family and domain databases
InterPro	IPR004000. Actin-like. IPR004001. Actin_CS. [Graphical view]
PANTHER	PTHR11937. Actin_like. 1 hit.
Pfam	PF00022. Actin. 1 hit. [Graphical view]
PRINTS	PR00190. ACTIN.
SMART	SM00268. ACTIN. 1 hit. [Graphical view]
PROSITE	PS00406. ACTINS_1. 1 hit. PS00432. ACTINS_2. 1 hit. PS01132. ACTINS_ACT_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACT_CANAL

Accession

Primary (citable) accession number: P14235

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 1, 1990
Last sequence update:	January 1, 1990
Last modified:	November 24, 2009
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)