Reviewed, UniProtKB/Swiss-Prot P14198 (AAC4_DICDI)

Names and origin

Protein names

Recommended name:
    AAC-rich mRNA clone AAC4 protein

Gene names

Name:	AAC4
ORF Names:	DDB_G0267458

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	351 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Developmental stage	The concentration of AAC-rich mRNAs is low in dormant spores and growing cells, but increases during spore-germination and multicellular development. Ref.2
Miscellaneous	Several proteins derive from AAC-rich mRNA, which, due to a frameshift also have ACA and CAA codons and thus are Asn-, Thr- or Gln-rich.
Sequence caution	The sequence CAA34530.1 differs from that shown. Reason: Frameshift at position 313.

Ontologies

Keywords
Domain	Repeat
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 351	351	AAC-rich mRNA clone AAC4 protein		PRO_0000064414
Regions
	Compositional bias	28 – 95	68	Asn-rich
	Compositional bias	124 – 128	5	Poly-Glu
	Compositional bias	280 – 346	67	Gln-rich
Experimental info
	Sequence conflict	51	1	K → E in CAA34530. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P14198-1 [UniParc]. Last modified December 4, 2007. Version 2. Checksum: 7842663B8BFFEF76	FASTA	351	40,223
	10 20 30 40 50 60 MSLSNNQTQF VTVFVPIQLS IDVFRKMNNI NSFVNDNLTN FPIVTVDQLI KVVNNNNNNN 70 80 90 100 110 120 NNNNNNNNNN NNNTSISNNG DINNCLATFE QVQNNCFETC DFKATEREHY FASGKQIQES 130 140 150 160 170 180 VLPEEEEEKI SVNNFAMVTV EPNNCFVKAQ QINSVAPLSL DNRNCVRRAH REVNTFVQVF 190 200 210 220 230 240 DVCVFNLKVV NVATNESQVN LFNGGNVENI CFDRSIQMPR SSADDFDWSS QQQSSWYSLA 250 260 270 280 290 300 LSIIPIYHEI IISSLQLVSS CLLQVLAASA TKATTSTSTQ HHRSQCFQKN CCKPQQSINK 310 320 330 340 350 SYLYQLPKKH LLLKQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQNQQQPIKS F

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.
[2]	"Nucleotide sequences of Dictyostelium discoideum developmentally regulated cDNAs rich in (AAC) imply proteins that contain clusters of asparagine, glutamine, or threonine." Shaw D.R., Richter H., Giorda R., Ohmachi T., Ennis H.L. Mol. Gen. Genet. 218:453-459(1989) [PubMed: 2511421] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-317, DEVELOPMENTAL STAGE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000003 Genomic DNA. Translation: EAL73182.1. X16523 mRNA. Translation: CAA34530.1. Frameshift.
PIR	S05356.
RefSeq	XP_647067.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3398823.
KEGG	ddi:DDB_0191504.
Organism-specific databases
dictyBase	DDB_G0267458. AAC4.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

AAC4_DICDI

Accession

Primary (citable) accession number: P14198
Secondary accession number(s): Q55GW7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 1, 1990
Last sequence update:	December 4, 2007
Last modified:	November 25, 2008
This is version 37 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)