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Protein

Protein RecA

Gene

recA

Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi69 – 76ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA recombination, DNA repair, SOS response
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVAR240292:G7WH-5969-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecAUniRule annotation
Alternative name(s):
Recombinase AUniRule annotation
Gene namesi
Name:recAUniRule annotation
Ordered Locus Names:Ava_4925
OrganismiAnabaena variabilis (strain ATCC 29413 / PCC 7937)
Taxonomic identifieri240292 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeAnabaena
Proteomesi
  • UP000002533 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001226411 – 358Protein RecAAdd BLAST358

Proteomic databases

PRIDEiP14167.

Interactioni

Protein-protein interaction databases

STRINGi240292.Ava_4925.

Structurei

3D structure databases

ProteinModelPortaliP14167.
SMRiP14167.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C68. Bacteria.
COG0468. LUCA.
HOGENOMiHOG000264120.
KOiK03553.
OMAiSKMGLQA.
OrthoDBiPOG091H01OP.

Family and domain databases

CDDicd00983. recA. 1 hit.
Gene3Di3.30.250.10. 1 hit.
HAMAPiMF_00268. RecA. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
PANTHERiPTHR22942:SF52. PTHR22942:SF52. 1 hit.
PfamiView protein in Pfam
PF00154. RecA. 1 hit.
PRINTSiPR00142. RECA.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsiTIGR02012. tigrfam_recA. 1 hit.
PROSITEiView protein in PROSITE
PS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.

Sequencei

Sequence statusi: Complete.

P14167-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAINTDTSGK QKALTMVLNQ IERSFGKGAI MRLGDATRMR VETISTGALT
60 70 80 90 100
LDLALGGGLP KGRVIEIYGP ESSGKTTVAL HAIAEVQKEG GIAAFVDAEH
110 120 130 140 150
ALDPTYASAL GVDIQNLLVS QPDTGESALE IVDQLVRSAA VDIVVIDSVA
160 170 180 190 200
ALVPRAEIEG DMGDAHVGLQ ARLMSQALRK ITGNIGKSGC TVIFINQLRQ
210 220 230 240 250
KIGVTYGSPE TTTGGNALKF YASVRLDIRR IQTLKKGTDE FGNRVKVKVA
260 270 280 290 300
KNKVAPPFRI AEFDIIFGKG VSTLGCLVDL AEETGILLRK GAWYSYNGDN
310 320 330 340 350
ISQGRDNAIK YLEEKPEFAE QIKQQVREKL DKGAVVSANS VAKANEEDEE

DVDLDEEE
Length:358
Mass (Da):38,447
Last modified:April 4, 2006 - v2
Checksum:i055940C869AEE5FF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti61K → R in AAA22031 (PubMed:2507530).Curated1
Sequence conflicti100H → Q in AAA22031 (PubMed:2507530).Curated1
Sequence conflicti137R → P in AAA22031 (PubMed:2507530).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M29680 Genomic DNA. Translation: AAA22031.1.
CP000117 Genomic DNA. Translation: ABA24522.1.
PIRiA33606. RQAIA.

Genome annotation databases

EnsemblBacteriaiABA24522; ABA24522; Ava_4925.
KEGGiava:Ava_4925.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRECA_ANAVT
AccessioniPrimary (citable) accession number: P14167
Secondary accession number(s): Q3M3B4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: April 4, 2006
Last modified: June 7, 2017
This is version 122 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families