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Protein

50S ribosomal protein L6

Gene

rpl6

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciHMAR272569:GJDH-1452-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L6UniRule annotation
Alternative name(s):
Hl10
Hmal6
Gene namesi
Name:rpl6UniRule annotation
Ordered Locus Names:rrnAC1596
OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Taxonomic identifieri272569 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloarcula
Proteomesi
  • UP000001169 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved2 Publications
Chaini2 – 17817750S ribosomal protein L6PRO_0000131083Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Interacts weakly with protein L13.UniRule annotation2 Publications

Protein-protein interaction databases

STRINGi272569.rrnAC1596.

Structurei

Secondary structure

1
178
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 75Combined sources
Beta strandi13 – 175Combined sources
Beta strandi20 – 256Combined sources
Beta strandi28 – 336Combined sources
Beta strandi40 – 445Combined sources
Beta strandi47 – 515Combined sources
Helixi57 – 7721Combined sources
Beta strandi81 – 888Combined sources
Beta strandi90 – 923Combined sources
Beta strandi95 – 995Combined sources
Beta strandi102 – 1076Combined sources
Helixi108 – 1103Combined sources
Beta strandi115 – 1184Combined sources
Beta strandi124 – 1285Combined sources
Beta strandi131 – 1377Combined sources
Helixi139 – 15113Combined sources
Beta strandi156 – 1583Combined sources
Turni160 – 1623Combined sources
Beta strandi166 – 1716Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1C04X-ray5.00B21-25[»]
1FFKX-ray2.4012-178[»]
1JJ2X-ray2.40E2-178[»]
1K73X-ray3.01G2-178[»]
1K8AX-ray3.00G2-178[»]
1K9MX-ray3.00G2-178[»]
1KC8X-ray3.01G2-178[»]
1KD1X-ray3.00G2-178[»]
1KQSX-ray3.10E2-178[»]
1M1KX-ray3.20G2-178[»]
1M90X-ray2.80G2-178[»]
1N8RX-ray3.00G2-178[»]
1NJIX-ray3.00G2-178[»]
1Q7YX-ray3.20G2-178[»]
1Q81X-ray2.95G2-178[»]
1Q82X-ray2.98G2-178[»]
1Q86X-ray3.00G2-178[»]
1QVFX-ray3.10E2-178[»]
1QVGX-ray2.90E2-178[»]
1S72X-ray2.40E1-178[»]
1VQ4X-ray2.70E1-178[»]
1VQ5X-ray2.60E1-178[»]
1VQ6X-ray2.70E1-178[»]
1VQ7X-ray2.50E1-178[»]
1VQ8X-ray2.20E1-178[»]
1VQ9X-ray2.40E1-178[»]
1VQKX-ray2.30E1-178[»]
1VQLX-ray2.30E1-178[»]
1VQMX-ray2.30E1-178[»]
1VQNX-ray2.40E1-178[»]
1VQOX-ray2.20E1-178[»]
1VQPX-ray2.25E1-178[»]
1W2BX-ray3.50E2-178[»]
1YHQX-ray2.40E1-178[»]
1YI2X-ray2.65E1-178[»]
1YIJX-ray2.60E1-178[»]
1YITX-ray2.80E1-178[»]
1YJ9X-ray2.90E1-178[»]
1YJNX-ray3.00E1-178[»]
1YJWX-ray2.90E1-178[»]
2OTJX-ray2.90E1-178[»]
2OTLX-ray2.70E1-178[»]
2QA4X-ray3.00E1-178[»]
2QEXX-ray2.90E1-178[»]
3CC2X-ray2.40E1-178[»]
3CC4X-ray2.70E1-178[»]
3CC7X-ray2.70E1-178[»]
3CCEX-ray2.75E1-178[»]
3CCJX-ray2.70E1-178[»]
3CCLX-ray2.90E1-178[»]
3CCMX-ray2.55E1-178[»]
3CCQX-ray2.90E1-178[»]
3CCRX-ray3.00E1-178[»]
3CCSX-ray2.95E1-178[»]
3CCUX-ray2.80E1-178[»]
3CCVX-ray2.90E1-178[»]
3CD6X-ray2.75E1-178[»]
3CMAX-ray2.80E1-178[»]
3CMEX-ray2.95E1-178[»]
3CPWX-ray2.70E1-178[»]
3CXCX-ray3.00E2-178[»]
3G4SX-ray3.20E2-173[»]
3G6EX-ray2.70E2-173[»]
3G71X-ray2.85E2-173[»]
3I55X-ray3.11E1-178[»]
3I56X-ray2.90E1-178[»]
3OW2X-ray2.70E2-173[»]
4ADXelectron microscopy6.60E1-178[»]
4V9FX-ray2.40E1-178[»]
ProteinModelPortaliP14135.
SMRiP14135. Positions 2-173.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP14135.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L6P family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04090. Archaea.
COG0097. LUCA.
HOGENOMiHOG000039905.
KOiK02933.
OMAiRLWYPDI.

Family and domain databases

Gene3Di3.90.930.12. 2 hits.
HAMAPiMF_01365_A. Ribosomal_L6_A. 1 hit.
InterProiIPR000702. Ribosomal_L6.
IPR020040. Ribosomal_L6_a/b-dom.
IPR002359. Ribosomal_L6_CS2.
IPR019907. Ribosomal_L6P_arc.
[Graphical view]
PANTHERiPTHR11655. PTHR11655. 1 hit.
PfamiPF00347. Ribosomal_L6. 2 hits.
[Graphical view]
PIRSFiPIRSF002162. Ribosomal_L6. 1 hit.
SUPFAMiSSF56053. SSF56053. 2 hits.
TIGRFAMsiTIGR03653. uL6_arch. 1 hit.
PROSITEiPS00700. RIBOSOMAL_L6_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P14135-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRVELEIPE DVDAEQDHLD ITVEGDNGSV TRRLWYPDID VSVDGDTVVI
60 70 80 90 100
ESDEDNAKTM STIGTFQSHI ENMFHGVTEG WEYGMEVFYS HFPMQVNVEG
110 120 130 140 150
DEVVIENFLG EKAPRRTTIH GDTDVEIDGE ELTVSGPDIE AVGQTAADIE
160 170
QLTRINDKDV RVFQDGVYIT RKPNRGDA
Length:178
Mass (Da):19,944
Last modified:January 23, 2007 - v3
Checksum:i380872452165689C
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti3 – 31R → S.
Natural varianti24 – 241E → S.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X58395 Genomic DNA. Translation: CAA41287.1.
AY596297 Genomic DNA. Translation: AAV46514.1.
PIRiS16538. R5HS6L.
RefSeqiWP_011223740.1. NC_006396.1.

Genome annotation databases

EnsemblBacteriaiAAV46514; AAV46514; rrnAC1596.
GeneIDi3127517.
KEGGihma:rrnAC1596.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X58395 Genomic DNA. Translation: CAA41287.1.
AY596297 Genomic DNA. Translation: AAV46514.1.
PIRiS16538. R5HS6L.
RefSeqiWP_011223740.1. NC_006396.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1C04X-ray5.00B21-25[»]
1FFKX-ray2.4012-178[»]
1JJ2X-ray2.40E2-178[»]
1K73X-ray3.01G2-178[»]
1K8AX-ray3.00G2-178[»]
1K9MX-ray3.00G2-178[»]
1KC8X-ray3.01G2-178[»]
1KD1X-ray3.00G2-178[»]
1KQSX-ray3.10E2-178[»]
1M1KX-ray3.20G2-178[»]
1M90X-ray2.80G2-178[»]
1N8RX-ray3.00G2-178[»]
1NJIX-ray3.00G2-178[»]
1Q7YX-ray3.20G2-178[»]
1Q81X-ray2.95G2-178[»]
1Q82X-ray2.98G2-178[»]
1Q86X-ray3.00G2-178[»]
1QVFX-ray3.10E2-178[»]
1QVGX-ray2.90E2-178[»]
1S72X-ray2.40E1-178[»]
1VQ4X-ray2.70E1-178[»]
1VQ5X-ray2.60E1-178[»]
1VQ6X-ray2.70E1-178[»]
1VQ7X-ray2.50E1-178[»]
1VQ8X-ray2.20E1-178[»]
1VQ9X-ray2.40E1-178[»]
1VQKX-ray2.30E1-178[»]
1VQLX-ray2.30E1-178[»]
1VQMX-ray2.30E1-178[»]
1VQNX-ray2.40E1-178[»]
1VQOX-ray2.20E1-178[»]
1VQPX-ray2.25E1-178[»]
1W2BX-ray3.50E2-178[»]
1YHQX-ray2.40E1-178[»]
1YI2X-ray2.65E1-178[»]
1YIJX-ray2.60E1-178[»]
1YITX-ray2.80E1-178[»]
1YJ9X-ray2.90E1-178[»]
1YJNX-ray3.00E1-178[»]
1YJWX-ray2.90E1-178[»]
2OTJX-ray2.90E1-178[»]
2OTLX-ray2.70E1-178[»]
2QA4X-ray3.00E1-178[»]
2QEXX-ray2.90E1-178[»]
3CC2X-ray2.40E1-178[»]
3CC4X-ray2.70E1-178[»]
3CC7X-ray2.70E1-178[»]
3CCEX-ray2.75E1-178[»]
3CCJX-ray2.70E1-178[»]
3CCLX-ray2.90E1-178[»]
3CCMX-ray2.55E1-178[»]
3CCQX-ray2.90E1-178[»]
3CCRX-ray3.00E1-178[»]
3CCSX-ray2.95E1-178[»]
3CCUX-ray2.80E1-178[»]
3CCVX-ray2.90E1-178[»]
3CD6X-ray2.75E1-178[»]
3CMAX-ray2.80E1-178[»]
3CMEX-ray2.95E1-178[»]
3CPWX-ray2.70E1-178[»]
3CXCX-ray3.00E2-178[»]
3G4SX-ray3.20E2-173[»]
3G6EX-ray2.70E2-173[»]
3G71X-ray2.85E2-173[»]
3I55X-ray3.11E1-178[»]
3I56X-ray2.90E1-178[»]
3OW2X-ray2.70E2-173[»]
4ADXelectron microscopy6.60E1-178[»]
4V9FX-ray2.40E1-178[»]
ProteinModelPortaliP14135.
SMRiP14135. Positions 2-173.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272569.rrnAC1596.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV46514; AAV46514; rrnAC1596.
GeneIDi3127517.
KEGGihma:rrnAC1596.

Phylogenomic databases

eggNOGiarCOG04090. Archaea.
COG0097. LUCA.
HOGENOMiHOG000039905.
KOiK02933.
OMAiRLWYPDI.

Enzyme and pathway databases

BioCyciHMAR272569:GJDH-1452-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP14135.

Family and domain databases

Gene3Di3.90.930.12. 2 hits.
HAMAPiMF_01365_A. Ribosomal_L6_A. 1 hit.
InterProiIPR000702. Ribosomal_L6.
IPR020040. Ribosomal_L6_a/b-dom.
IPR002359. Ribosomal_L6_CS2.
IPR019907. Ribosomal_L6P_arc.
[Graphical view]
PANTHERiPTHR11655. PTHR11655. 1 hit.
PfamiPF00347. Ribosomal_L6. 2 hits.
[Graphical view]
PIRSFiPIRSF002162. Ribosomal_L6. 1 hit.
SUPFAMiSSF56053. SSF56053. 2 hits.
TIGRFAMsiTIGR03653. uL6_arch. 1 hit.
PROSITEiPS00700. RIBOSOMAL_L6_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL6_HALMA
AccessioniPrimary (citable) accession number: P14135
Secondary accession number(s): P12739, Q5V1T8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 23, 2007
Last modified: December 9, 2015
This is version 127 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.