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P14131

- RS16_MOUSE

UniProt

P14131 - RS16_MOUSE

Protein

40S ribosomal protein S16

Gene

Rps16

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. RNA binding Source: Ensembl
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. ribosomal small subunit biogenesis Source: Ensembl
    2. rRNA processing Source: Ensembl
    3. translation Source: InterPro

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    ReactomeiREACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    40S ribosomal protein S16
    Gene namesi
    Name:Rps16
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:98118. Rps16.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosolic small ribosomal subunit Source: Ensembl
    2. small ribosomal subunit Source: UniProtKB

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 14614540S ribosomal protein S16PRO_0000111480Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei60 – 601N6-acetyllysineBy similarity

    Keywords - PTMi

    Acetylation

    Proteomic databases

    MaxQBiP14131.
    PaxDbiP14131.
    PRIDEiP14131.

    PTM databases

    PhosphoSiteiP14131.

    Expressioni

    Gene expression databases

    BgeeiP14131.
    CleanExiMM_RPS16.
    GenevestigatoriP14131.

    Interactioni

    Protein-protein interaction databases

    BioGridi203004. 3 interactions.
    IntActiP14131. 5 interactions.
    MINTiMINT-1856568.

    Structurei

    3D structure databases

    ProteinModelPortaliP14131.
    SMRiP14131. Positions 6-146.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein S9P family.Curated

    Phylogenomic databases

    eggNOGiCOG0103.
    GeneTreeiENSGT00390000013067.
    HOVERGENiHBG055171.
    InParanoidiP14131.
    KOiK02960.
    OMAiNRRCEPK.
    OrthoDBiEOG754HQW.
    TreeFamiTF300088.

    Family and domain databases

    Gene3Di3.30.230.10. 1 hit.
    InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR000754. Ribosomal_S9.
    IPR020574. Ribosomal_S9_CS.
    [Graphical view]
    PANTHERiPTHR21569. PTHR21569. 1 hit.
    PfamiPF00380. Ribosomal_S9. 1 hit.
    [Graphical view]
    SUPFAMiSSF54211. SSF54211. 1 hit.
    PROSITEiPS00360. RIBOSOMAL_S9. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P14131-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPSKGPLQSV QVFGRKKTAT AVAHCKRGNG LIKVNGRPLE MIEPRTLQYK    50
    LLEPVLLLGK ERFAGVDIRV RVKGGGHVAQ IYAIRQSISK ALVAYYQKYV 100
    DEASKKEIKD ILIQYDRTLL VADPRRCESK KFGGPGARAR YQKSYR 146
    Length:146
    Mass (Da):16,445
    Last modified:January 23, 2007 - v4
    Checksum:i519BCFB91BB68A15
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti19 – 202AT → L in AAA03646. (PubMed:3915781)Curated
    Sequence conflicti46 – 461T → A in AAA03646. (PubMed:3915781)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M11408 Unassigned DNA. Translation: AAA03646.1.
    AK010613 mRNA. Translation: BAB27062.1.
    AK010641 mRNA. Translation: BAB27083.1.
    AK011060 mRNA. Translation: BAB27368.1.
    AK019400 mRNA. Translation: BAB31702.1.
    AK083946 mRNA. Translation: BAC39077.1.
    AK088413 mRNA. Translation: BAC40341.1.
    AK088716 mRNA. Translation: BAC40524.1.
    AK150808 mRNA. Translation: BAE29871.1.
    AK168207 mRNA. Translation: BAE40167.1.
    AK169328 mRNA. Translation: BAE41081.1.
    CCDSiCCDS39858.1.
    PIRiS11623. R3MS16.
    RefSeqiNP_038675.2. NM_013647.2.
    UniGeneiMm.702.

    Genome annotation databases

    EnsembliENSMUST00000082134; ENSMUSP00000103940; ENSMUSG00000037563.
    GeneIDi20055.
    KEGGimmu:20055.
    UCSCiuc012fgr.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M11408 Unassigned DNA. Translation: AAA03646.1 .
    AK010613 mRNA. Translation: BAB27062.1 .
    AK010641 mRNA. Translation: BAB27083.1 .
    AK011060 mRNA. Translation: BAB27368.1 .
    AK019400 mRNA. Translation: BAB31702.1 .
    AK083946 mRNA. Translation: BAC39077.1 .
    AK088413 mRNA. Translation: BAC40341.1 .
    AK088716 mRNA. Translation: BAC40524.1 .
    AK150808 mRNA. Translation: BAE29871.1 .
    AK168207 mRNA. Translation: BAE40167.1 .
    AK169328 mRNA. Translation: BAE41081.1 .
    CCDSi CCDS39858.1.
    PIRi S11623. R3MS16.
    RefSeqi NP_038675.2. NM_013647.2.
    UniGenei Mm.702.

    3D structure databases

    ProteinModelPortali P14131.
    SMRi P14131. Positions 6-146.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 203004. 3 interactions.
    IntActi P14131. 5 interactions.
    MINTi MINT-1856568.

    PTM databases

    PhosphoSitei P14131.

    Proteomic databases

    MaxQBi P14131.
    PaxDbi P14131.
    PRIDEi P14131.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000082134 ; ENSMUSP00000103940 ; ENSMUSG00000037563 .
    GeneIDi 20055.
    KEGGi mmu:20055.
    UCSCi uc012fgr.1. mouse.

    Organism-specific databases

    CTDi 6217.
    MGIi MGI:98118. Rps16.

    Phylogenomic databases

    eggNOGi COG0103.
    GeneTreei ENSGT00390000013067.
    HOVERGENi HBG055171.
    InParanoidi P14131.
    KOi K02960.
    OMAi NRRCEPK.
    OrthoDBi EOG754HQW.
    TreeFami TF300088.

    Enzyme and pathway databases

    Reactomei REACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Miscellaneous databases

    NextBioi 297567.
    PROi P14131.
    SOURCEi Search...

    Gene expression databases

    Bgeei P14131.
    CleanExi MM_RPS16.
    Genevestigatori P14131.

    Family and domain databases

    Gene3Di 3.30.230.10. 1 hit.
    InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR000754. Ribosomal_S9.
    IPR020574. Ribosomal_S9_CS.
    [Graphical view ]
    PANTHERi PTHR21569. PTHR21569. 1 hit.
    Pfami PF00380. Ribosomal_S9. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54211. SSF54211. 1 hit.
    PROSITEi PS00360. RIBOSOMAL_S9. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of the multigene family encoding the mouse S16 ribosomal protein: strategy for distinguishing an expressed gene from its processed pseudogene counterparts by an analysis of total genomic DNA."
      Wagner M., Perry R.P.
      Mol. Cell. Biol. 5:3560-3576(1985) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J and NOD.
      Tissue: Bone marrow, Head, Kidney, Liver, Spinal ganglion and Thymus.

    Entry informationi

    Entry nameiRS16_MOUSE
    AccessioniPrimary (citable) accession number: P14131
    Secondary accession number(s): Q3THM9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 1, 1990
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 113 of the entry and version 4 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3