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Protein

40S ribosomal protein S16

Gene

Rps16

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. poly(A) RNA binding Source: MGI
  2. RNA binding Source: MGI
  3. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. ribosomal small subunit biogenesis Source: MGI
  2. rRNA processing Source: MGI
  3. translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiREACT_279505. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_283953. Formation of the ternary complex, and subsequently, the 43S complex.
REACT_292264. GTP hydrolysis and joining of the 60S ribosomal subunit.
REACT_292503. Translation initiation complex formation.
REACT_302277. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_305839. Ribosomal scanning and start codon recognition.
REACT_308559. Formation of a pool of free 40S subunits.
REACT_311765. Peptide chain elongation.
REACT_319670. Eukaryotic Translation Termination.
REACT_331340. SRP-dependent cotranslational protein targeting to membrane.
REACT_340387. L13a-mediated translational silencing of Ceruloplasmin expression.

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S16
Gene namesi
Name:Rps16
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:98118. Rps16.

Subcellular locationi

GO - Cellular componenti

  1. cytosolic small ribosomal subunit Source: MGI
  2. extracellular vesicular exosome Source: MGI
  3. focal adhesion Source: MGI
  4. membrane Source: MGI
  5. small ribosomal subunit Source: UniProtKB
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 14614540S ribosomal protein S16PRO_0000111480Add
BLAST

Proteomic databases

MaxQBiP14131.
PaxDbiP14131.
PRIDEiP14131.

PTM databases

PhosphoSiteiP14131.

Expressioni

Gene expression databases

BgeeiP14131.
CleanExiMM_RPS16.
ExpressionAtlasiP14131. baseline and differential.
GenevestigatoriP14131.

Interactioni

Protein-protein interaction databases

BioGridi203004. 3 interactions.
IntActiP14131. 5 interactions.
MINTiMINT-1856568.

Structurei

3D structure databases

ProteinModelPortaliP14131.
SMRiP14131. Positions 6-146.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S9P family.Curated

Phylogenomic databases

eggNOGiCOG0103.
GeneTreeiENSGT00390000013067.
HOVERGENiHBG055171.
InParanoidiP14131.
KOiK02960.
OMAiNRRCEPK.
OrthoDBiEOG754HQW.
TreeFamiTF300088.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000754. Ribosomal_S9.
IPR020574. Ribosomal_S9_CS.
[Graphical view]
PANTHERiPTHR21569. PTHR21569. 1 hit.
PfamiPF00380. Ribosomal_S9. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
PROSITEiPS00360. RIBOSOMAL_S9. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P14131-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSKGPLQSV QVFGRKKTAT AVAHCKRGNG LIKVNGRPLE MIEPRTLQYK
60 70 80 90 100
LLEPVLLLGK ERFAGVDIRV RVKGGGHVAQ IYAIRQSISK ALVAYYQKYV
110 120 130 140
DEASKKEIKD ILIQYDRTLL VADPRRCESK KFGGPGARAR YQKSYR
Length:146
Mass (Da):16,445
Last modified:January 23, 2007 - v4
Checksum:i519BCFB91BB68A15
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti19 – 202AT → L in AAA03646 (PubMed:3915781).Curated
Sequence conflicti46 – 461T → A in AAA03646 (PubMed:3915781).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M11408 Unassigned DNA. Translation: AAA03646.1.
AK010613 mRNA. Translation: BAB27062.1.
AK010641 mRNA. Translation: BAB27083.1.
AK011060 mRNA. Translation: BAB27368.1.
AK019400 mRNA. Translation: BAB31702.1.
AK083946 mRNA. Translation: BAC39077.1.
AK088413 mRNA. Translation: BAC40341.1.
AK088716 mRNA. Translation: BAC40524.1.
AK150808 mRNA. Translation: BAE29871.1.
AK168207 mRNA. Translation: BAE40167.1.
AK169328 mRNA. Translation: BAE41081.1.
CCDSiCCDS39858.1.
PIRiS11623. R3MS16.
RefSeqiNP_038675.2. NM_013647.2.
UniGeneiMm.702.

Genome annotation databases

EnsembliENSMUST00000082134; ENSMUSP00000103940; ENSMUSG00000037563.
GeneIDi20055.
KEGGimmu:20055.
UCSCiuc012fgr.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M11408 Unassigned DNA. Translation: AAA03646.1.
AK010613 mRNA. Translation: BAB27062.1.
AK010641 mRNA. Translation: BAB27083.1.
AK011060 mRNA. Translation: BAB27368.1.
AK019400 mRNA. Translation: BAB31702.1.
AK083946 mRNA. Translation: BAC39077.1.
AK088413 mRNA. Translation: BAC40341.1.
AK088716 mRNA. Translation: BAC40524.1.
AK150808 mRNA. Translation: BAE29871.1.
AK168207 mRNA. Translation: BAE40167.1.
AK169328 mRNA. Translation: BAE41081.1.
CCDSiCCDS39858.1.
PIRiS11623. R3MS16.
RefSeqiNP_038675.2. NM_013647.2.
UniGeneiMm.702.

3D structure databases

ProteinModelPortaliP14131.
SMRiP14131. Positions 6-146.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi203004. 3 interactions.
IntActiP14131. 5 interactions.
MINTiMINT-1856568.

PTM databases

PhosphoSiteiP14131.

Proteomic databases

MaxQBiP14131.
PaxDbiP14131.
PRIDEiP14131.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000082134; ENSMUSP00000103940; ENSMUSG00000037563.
GeneIDi20055.
KEGGimmu:20055.
UCSCiuc012fgr.1. mouse.

Organism-specific databases

CTDi6217.
MGIiMGI:98118. Rps16.

Phylogenomic databases

eggNOGiCOG0103.
GeneTreeiENSGT00390000013067.
HOVERGENiHBG055171.
InParanoidiP14131.
KOiK02960.
OMAiNRRCEPK.
OrthoDBiEOG754HQW.
TreeFamiTF300088.

Enzyme and pathway databases

ReactomeiREACT_279505. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_283953. Formation of the ternary complex, and subsequently, the 43S complex.
REACT_292264. GTP hydrolysis and joining of the 60S ribosomal subunit.
REACT_292503. Translation initiation complex formation.
REACT_302277. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_305839. Ribosomal scanning and start codon recognition.
REACT_308559. Formation of a pool of free 40S subunits.
REACT_311765. Peptide chain elongation.
REACT_319670. Eukaryotic Translation Termination.
REACT_331340. SRP-dependent cotranslational protein targeting to membrane.
REACT_340387. L13a-mediated translational silencing of Ceruloplasmin expression.

Miscellaneous databases

NextBioi297567.
PROiP14131.
SOURCEiSearch...

Gene expression databases

BgeeiP14131.
CleanExiMM_RPS16.
ExpressionAtlasiP14131. baseline and differential.
GenevestigatoriP14131.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000754. Ribosomal_S9.
IPR020574. Ribosomal_S9_CS.
[Graphical view]
PANTHERiPTHR21569. PTHR21569. 1 hit.
PfamiPF00380. Ribosomal_S9. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
PROSITEiPS00360. RIBOSOMAL_S9. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Characterization of the multigene family encoding the mouse S16 ribosomal protein: strategy for distinguishing an expressed gene from its processed pseudogene counterparts by an analysis of total genomic DNA."
    Wagner M., Perry R.P.
    Mol. Cell. Biol. 5:3560-3576(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J and NOD.
    Tissue: Bone marrow, Head, Kidney, Liver, Spinal ganglion and Thymus.

Entry informationi

Entry nameiRS16_MOUSE
AccessioniPrimary (citable) accession number: P14131
Secondary accession number(s): Q3THM9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 23, 2007
Last modified: April 1, 2015
This is version 119 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.