Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

40S ribosomal protein S17-B

Gene

RPS17B

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.1 Publication

Miscellaneous

Present with 30500 molecules/cell in log phase SD medium.1 Publication
There are 2 genes for eS17 in yeast.Curated

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • cytoplasmic translation Source: SGD
  • ribosomal small subunit assembly Source: SGD

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-29978-MONOMER
ReactomeiR-SCE-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-SCE-1799339 SRP-dependent cotranslational protein targeting to membrane
R-SCE-72689 Formation of a pool of free 40S subunits
R-SCE-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-SCE-72702 Ribosomal scanning and start codon recognition
R-SCE-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-SCE-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-SCE-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S17-B1 Publication
Alternative name(s):
RP51B
Small ribosomal subunit protein eS17-B1 Publication
Gene namesi
Name:RPS17B1 Publication
Synonyms:RP51B
Ordered Locus Names:YDR447C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR447C
SGDiS000002855 RPS17B

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001415471 – 13640S ribosomal protein S17-BAdd BLAST136

Proteomic databases

MaxQBiP14127
PaxDbiP14127
PRIDEiP14127

PTM databases

iPTMnetiP14127

Interactioni

Subunit structurei

Component of the small ribosomal subunit (SSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes) (PubMed:9559554, PubMed:22096102).1 Publication1 Publication

Protein-protein interaction databases

BioGridi32502, 163 interactors
IntActiP14127, 62 interactors
MINTiP14127
STRINGi4932.YDR447C

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5M1Jelectron microscopy3.30R22-126[»]
5MC6electron microscopy3.80G1-136[»]
5MEIX-ray3.50S2-126[»]
5TGAX-ray3.30C7/c72-126[»]
ProteinModelPortaliP14127
SMRiP14127
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

GeneTreeiENSGT00390000006548
HOGENOMiHOG000227166
InParanoidiP14127
KOiK02962
OMAiATHLMRR

Family and domain databases

Gene3Di1.10.60.20, 1 hit
HAMAPiMF_00511 Ribosomal_S17e, 1 hit
InterProiView protein in InterPro
IPR001210 Ribosomal_S17e
IPR018273 Ribosomal_S17e_CS
IPR036401 RPS17e-like_sf
PANTHERiPTHR10732 PTHR10732, 1 hit
PfamiView protein in Pfam
PF00833 Ribosomal_S17e, 1 hit
SUPFAMiSSF116820 SSF116820, 1 hit
PROSITEiView protein in PROSITE
PS00712 RIBOSOMAL_S17E, 1 hit

Sequencei

Sequence statusi: Complete.

P14127-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRVRTKTVK RASKALIERY YPKLTLDFQT NKRLCDEIAT IQSKRLRNKI
60 70 80 90 100
AGYTTHLMKR IQKGPVRGIS FKLQEEERER KDQYVPEVSA LDLSRSNGVL
110 120 130
NVDNQTSDLV KSLGLKLPLS VINVSAQRDR RYRKRN
Length:136
Mass (Da):15,803
Last modified:January 1, 1990 - v1
Checksum:i83EE5382870EA289
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K02480 Genomic DNA Translation: AAA34991.1
U33007 Genomic DNA Translation: AAB64890.1
BK006938 Genomic DNA Translation: DAA12282.1
PIRiS20161 R4BY7B
RefSeqiNP_010735.3, NM_001180755.3

Genome annotation databases

EnsemblFungiiYDR447C; YDR447C; YDR447C
GeneIDi852058
KEGGisce:YDR447C

Similar proteinsi

Entry informationi

Entry nameiRS17B_YEAST
AccessioniPrimary (citable) accession number: P14127
Secondary accession number(s): D6VT72
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: May 23, 2018
This is version 151 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health