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Protein

40S ribosomal protein S17-B

Gene

RPS17B

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.1 Publication

Miscellaneous

Present with 30500 molecules/cell in log phase SD medium.1 Publication
There are 2 genes for eS17 in yeast.Curated

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • cytoplasmic translation Source: SGD
  • ribosomal small subunit assembly Source: SGD

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-29978-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S17-B1 Publication
Alternative name(s):
RP51B
Small ribosomal subunit protein eS17-B1 Publication
Gene namesi
Name:RPS17B1 Publication
Synonyms:RP51B
Ordered Locus Names:YDR447C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR447C.
SGDiS000002855. RPS17B.

Subcellular locationi

GO - Cellular componenti

  • cytosolic small ribosomal subunit Source: SGD

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001415471 – 13640S ribosomal protein S17-BAdd BLAST136

Proteomic databases

MaxQBiP14127.
PRIDEiP14127.

PTM databases

iPTMnetiP14127.

Interactioni

Subunit structurei

Component of the small ribosomal subunit (SSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes) (PubMed:9559554, PubMed:22096102).1 Publication1 Publication

Protein-protein interaction databases

BioGridi32502. 159 interactors.
IntActiP14127. 62 interactors.
MINTiMINT-4482711.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5M1Jelectron microscopy3.30R22-126[»]
5MC6electron microscopy3.80G1-136[»]
5TGAX-ray3.30C7/c72-126[»]
ProteinModelPortaliP14127.
SMRiP14127.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000227166.
InParanoidiP14127.
KOiK02962.
OMAiYTTHLMR.

Family and domain databases

Gene3Di1.10.60.20. 1 hit.
HAMAPiMF_00511. Ribosomal_S17e. 1 hit.
InterProiView protein in InterPro
IPR001210. Ribosomal_S17e.
IPR018273. Ribosomal_S17e_CS.
PANTHERiPTHR10732. PTHR10732. 1 hit.
PfamiView protein in Pfam
PF00833. Ribosomal_S17e. 1 hit.
SUPFAMiSSF116820. SSF116820. 1 hit.
PROSITEiView protein in PROSITE
PS00712. RIBOSOMAL_S17E. 1 hit.

Sequencei

Sequence statusi: Complete.

P14127-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRVRTKTVK RASKALIERY YPKLTLDFQT NKRLCDEIAT IQSKRLRNKI
60 70 80 90 100
AGYTTHLMKR IQKGPVRGIS FKLQEEERER KDQYVPEVSA LDLSRSNGVL
110 120 130
NVDNQTSDLV KSLGLKLPLS VINVSAQRDR RYRKRN
Length:136
Mass (Da):15,803
Last modified:January 1, 1990 - v1
Checksum:i83EE5382870EA289
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K02480 Genomic DNA. Translation: AAA34991.1.
U33007 Genomic DNA. Translation: AAB64890.1.
BK006938 Genomic DNA. Translation: DAA12282.1.
PIRiS20161. R4BY7B.
RefSeqiNP_010735.3. NM_001180755.3.

Genome annotation databases

EnsemblFungiiYDR447C; YDR447C; YDR447C.
GeneIDi852058.
KEGGisce:YDR447C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K02480 Genomic DNA. Translation: AAA34991.1.
U33007 Genomic DNA. Translation: AAB64890.1.
BK006938 Genomic DNA. Translation: DAA12282.1.
PIRiS20161. R4BY7B.
RefSeqiNP_010735.3. NM_001180755.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5M1Jelectron microscopy3.30R22-126[»]
5MC6electron microscopy3.80G1-136[»]
5TGAX-ray3.30C7/c72-126[»]
ProteinModelPortaliP14127.
SMRiP14127.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32502. 159 interactors.
IntActiP14127. 62 interactors.
MINTiMINT-4482711.

PTM databases

iPTMnetiP14127.

Proteomic databases

MaxQBiP14127.
PRIDEiP14127.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYDR447C; YDR447C; YDR447C.
GeneIDi852058.
KEGGisce:YDR447C.

Organism-specific databases

EuPathDBiFungiDB:YDR447C.
SGDiS000002855. RPS17B.

Phylogenomic databases

HOGENOMiHOG000227166.
InParanoidiP14127.
KOiK02962.
OMAiYTTHLMR.

Enzyme and pathway databases

BioCyciYEAST:G3O-29978-MONOMER.

Miscellaneous databases

PROiPR:P14127.

Family and domain databases

Gene3Di1.10.60.20. 1 hit.
HAMAPiMF_00511. Ribosomal_S17e. 1 hit.
InterProiView protein in InterPro
IPR001210. Ribosomal_S17e.
IPR018273. Ribosomal_S17e_CS.
PANTHERiPTHR10732. PTHR10732. 1 hit.
PfamiView protein in Pfam
PF00833. Ribosomal_S17e. 1 hit.
SUPFAMiSSF116820. SSF116820. 1 hit.
PROSITEiView protein in PROSITE
PS00712. RIBOSOMAL_S17E. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRS17B_YEAST
AccessioniPrimary (citable) accession number: P14127
Secondary accession number(s): D6VT72
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: April 12, 2017
This is version 142 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.