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P14122

- RL11_HALMA

UniProt

P14122 - RL11_HALMA

Protein

50S ribosomal protein L11

Gene

rpl11

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 112 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.

    GO - Molecular functioni

    1. large ribosomal subunit rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Enzyme and pathway databases

    BioCyciHMAR272569:GJDH-1277-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L11UniRule annotation
    Alternative name(s):
    Hmal11
    Gene namesi
    Name:rpl11UniRule annotation
    Ordered Locus Names:rrnAC1414
    OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
    Taxonomic identifieri272569 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloarcula
    ProteomesiUP000001169: Chromosome I

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 16216150S ribosomal protein L11PRO_0000104431Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which 3 L12 dimers bind in a sequential fashion Probable.Curated

    Protein-protein interaction databases

    STRINGi272569.rrnAC1414.

    Structurei

    Secondary structure

    1
    162
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi12 – 143
    Turni18 – 236
    Turni33 – 364
    Helixi37 – 393
    Beta strandi52 – 554
    Beta strandi59 – 613
    Beta strandi63 – 653
    Helixi71 – 777
    Turni88 – 903
    Beta strandi94 – 974
    Helixi98 – 10710
    Turni108 – 1114
    Helixi117 – 12711
    Turni128 – 1325
    Beta strandi133 – 1364
    Helixi143 – 1486
    Turni149 – 1524
    Helixi153 – 1564

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1C04X-ray5.00C79-88[»]
    1S72X-ray2.40I1-162[»]
    1VQ4X-ray2.70I1-162[»]
    1VQ5X-ray2.60I1-162[»]
    1VQ6X-ray2.70I1-162[»]
    1VQ7X-ray2.50I1-162[»]
    1VQ8X-ray2.20I1-162[»]
    1VQ9X-ray2.40I1-162[»]
    1VQKX-ray2.30I1-162[»]
    1VQLX-ray2.30I1-162[»]
    1VQMX-ray2.30I1-162[»]
    1VQNX-ray2.40I1-162[»]
    1VQOX-ray2.20I1-162[»]
    1VQPX-ray2.25I1-162[»]
    1YHQX-ray2.40I1-162[»]
    1YI2X-ray2.65I1-162[»]
    1YIJX-ray2.60I1-162[»]
    1YITX-ray2.80I1-162[»]
    1YJ9X-ray2.90I1-162[»]
    1YJNX-ray3.00I1-162[»]
    1YJWX-ray2.90I1-162[»]
    2OTJX-ray2.90I2-162[»]
    2OTLX-ray2.70I1-162[»]
    2QA4X-ray3.00I1-162[»]
    2QEXX-ray2.90I1-162[»]
    3CC2X-ray2.40I1-162[»]
    3CC4X-ray2.70I1-162[»]
    3CC7X-ray2.70I1-162[»]
    3CCEX-ray2.75I1-162[»]
    3CCJX-ray2.70I1-162[»]
    3CCLX-ray2.90I1-162[»]
    3CCMX-ray2.55I1-162[»]
    3CCQX-ray2.90I1-162[»]
    3CCRX-ray3.00I1-162[»]
    3CCSX-ray2.95I1-162[»]
    3CCUX-ray2.80I1-162[»]
    3CCVX-ray2.90I1-162[»]
    3CD6X-ray2.75I1-162[»]
    3CMAX-ray2.80I1-162[»]
    3CMEX-ray2.95I1-162[»]
    3G4SX-ray3.20I67-136[»]
    3G6EX-ray2.70I67-136[»]
    3G71X-ray2.85I67-136[»]
    3I55X-ray3.11I1-162[»]
    3I56X-ray2.90I1-162[»]
    4HUBX-ray2.40I1-162[»]
    ProteinModelPortaliP14122.
    SMRiP14122. Positions 5-136.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP14122.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L11P family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0080.
    HOGENOMiHOG000082124.
    KOiK02867.
    OMAiLKIARMK.

    Family and domain databases

    Gene3Di1.10.10.250. 1 hit.
    3.30.1550.10. 1 hit.
    HAMAPiMF_00736. Ribosomal_L11.
    InterProiIPR000911. Ribosomal_L11/L12.
    IPR020783. Ribosomal_L11_C.
    IPR020785. Ribosomal_L11_CS.
    IPR020784. Ribosomal_L11_N.
    [Graphical view]
    PANTHERiPTHR11661. PTHR11661. 1 hit.
    PfamiPF00298. Ribosomal_L11. 1 hit.
    PF03946. Ribosomal_L11_N. 1 hit.
    [Graphical view]
    SMARTiSM00649. RL11. 1 hit.
    [Graphical view]
    SUPFAMiSSF46906. SSF46906. 1 hit.
    SSF54747. SSF54747. 1 hit.
    PROSITEiPS00359. RIBOSOMAL_L11. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P14122-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAGTIEVLVP GGEANPGPPL GPELGPTPVD VQAVVQEIND QTAAFDGTEV    50
    PVTVKYDDDG SFEIEVGVPP TAELIKDEAG FETGSGEPQE DFVADLSVDQ 100
    VKQIAEQKHP DLLSYDLTNA AKEVVGTCTS LGVTIEGENP REFKERIDAG 150
    EYDDVFAAEA QA 162
    Length:162
    Mass (Da):17,089
    Last modified:January 23, 2007 - v3
    Checksum:iE64E6802B49208B8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X51430 Genomic DNA. Translation: CAA35793.1.
    AY596297 Genomic DNA. Translation: AAV46342.1.
    PIRiS08420. R5HS11.
    RefSeqiWP_011223608.1. NC_006396.1.
    YP_136048.1. NC_006396.1.

    Genome annotation databases

    EnsemblBacteriaiAAV46342; AAV46342; rrnAC1414.
    GeneIDi3128412.
    KEGGihma:rrnAC1414.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X51430 Genomic DNA. Translation: CAA35793.1 .
    AY596297 Genomic DNA. Translation: AAV46342.1 .
    PIRi S08420. R5HS11.
    RefSeqi WP_011223608.1. NC_006396.1.
    YP_136048.1. NC_006396.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1C04 X-ray 5.00 C 79-88 [» ]
    1S72 X-ray 2.40 I 1-162 [» ]
    1VQ4 X-ray 2.70 I 1-162 [» ]
    1VQ5 X-ray 2.60 I 1-162 [» ]
    1VQ6 X-ray 2.70 I 1-162 [» ]
    1VQ7 X-ray 2.50 I 1-162 [» ]
    1VQ8 X-ray 2.20 I 1-162 [» ]
    1VQ9 X-ray 2.40 I 1-162 [» ]
    1VQK X-ray 2.30 I 1-162 [» ]
    1VQL X-ray 2.30 I 1-162 [» ]
    1VQM X-ray 2.30 I 1-162 [» ]
    1VQN X-ray 2.40 I 1-162 [» ]
    1VQO X-ray 2.20 I 1-162 [» ]
    1VQP X-ray 2.25 I 1-162 [» ]
    1YHQ X-ray 2.40 I 1-162 [» ]
    1YI2 X-ray 2.65 I 1-162 [» ]
    1YIJ X-ray 2.60 I 1-162 [» ]
    1YIT X-ray 2.80 I 1-162 [» ]
    1YJ9 X-ray 2.90 I 1-162 [» ]
    1YJN X-ray 3.00 I 1-162 [» ]
    1YJW X-ray 2.90 I 1-162 [» ]
    2OTJ X-ray 2.90 I 2-162 [» ]
    2OTL X-ray 2.70 I 1-162 [» ]
    2QA4 X-ray 3.00 I 1-162 [» ]
    2QEX X-ray 2.90 I 1-162 [» ]
    3CC2 X-ray 2.40 I 1-162 [» ]
    3CC4 X-ray 2.70 I 1-162 [» ]
    3CC7 X-ray 2.70 I 1-162 [» ]
    3CCE X-ray 2.75 I 1-162 [» ]
    3CCJ X-ray 2.70 I 1-162 [» ]
    3CCL X-ray 2.90 I 1-162 [» ]
    3CCM X-ray 2.55 I 1-162 [» ]
    3CCQ X-ray 2.90 I 1-162 [» ]
    3CCR X-ray 3.00 I 1-162 [» ]
    3CCS X-ray 2.95 I 1-162 [» ]
    3CCU X-ray 2.80 I 1-162 [» ]
    3CCV X-ray 2.90 I 1-162 [» ]
    3CD6 X-ray 2.75 I 1-162 [» ]
    3CMA X-ray 2.80 I 1-162 [» ]
    3CME X-ray 2.95 I 1-162 [» ]
    3G4S X-ray 3.20 I 67-136 [» ]
    3G6E X-ray 2.70 I 67-136 [» ]
    3G71 X-ray 2.85 I 67-136 [» ]
    3I55 X-ray 3.11 I 1-162 [» ]
    3I56 X-ray 2.90 I 1-162 [» ]
    4HUB X-ray 2.40 I 1-162 [» ]
    ProteinModelPortali P14122.
    SMRi P14122. Positions 5-136.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272569.rrnAC1414.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAV46342 ; AAV46342 ; rrnAC1414 .
    GeneIDi 3128412.
    KEGGi hma:rrnAC1414.

    Phylogenomic databases

    eggNOGi COG0080.
    HOGENOMi HOG000082124.
    KOi K02867.
    OMAi LKIARMK.

    Enzyme and pathway databases

    BioCyci HMAR272569:GJDH-1277-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei P14122.

    Family and domain databases

    Gene3Di 1.10.10.250. 1 hit.
    3.30.1550.10. 1 hit.
    HAMAPi MF_00736. Ribosomal_L11.
    InterProi IPR000911. Ribosomal_L11/L12.
    IPR020783. Ribosomal_L11_C.
    IPR020785. Ribosomal_L11_CS.
    IPR020784. Ribosomal_L11_N.
    [Graphical view ]
    PANTHERi PTHR11661. PTHR11661. 1 hit.
    Pfami PF00298. Ribosomal_L11. 1 hit.
    PF03946. Ribosomal_L11_N. 1 hit.
    [Graphical view ]
    SMARTi SM00649. RL11. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46906. SSF46906. 1 hit.
    SSF54747. SSF54747. 1 hit.
    PROSITEi PS00359. RIBOSOMAL_L11. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence of the genes encoding the L11, L1, L10 and L12 equivalent ribosomal proteins from the archaebacterium Halobacterium marismortui."
      Arndt E., Weigel C.
      Nucleic Acids Res. 18:1285-1285(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
    3. "Extended N-terminal sequencing of proteins of archaebacterial ribosomes blotted from two-dimensional gels onto glass fiber and poly(vinylidene difluoride) membrane."
      Walsh M.J., McDougall J., Wittmann-Liebold B.
      Biochemistry 27:6867-6876(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 2-28.
    4. "Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit."
      Ban N., Nissen P., Hansen J., Capel M., Moore P.B., Steitz T.A.
      Nature 400:841-847(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: 3D-STRUCTURE MODELING.
    5. "Structure of the base of the L7/L12 stalk of the Haloarcula marismortui large ribosomal subunit: analysis of L11 movements."
      Kavran J.M., Steitz T.A.
      J. Mol. Biol. 371:1047-1059(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS), RRNA-BINDING, INTERACTION WITH L10.
    6. "Revisiting the Haloarcula marismortui 50S ribosomal subunit model."
      Gabdulkhakov A., Nikonov S., Garber M.
      Acta Crystallogr. D 69:997-1004(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF THE 50S SUBUNIT.

    Entry informationi

    Entry nameiRL11_HALMA
    AccessioniPrimary (citable) accession number: P14122
    Secondary accession number(s): Q5V2B0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 1, 1990
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 112 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3