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P14121

- RL30_HALMA

UniProt

P14121 - RL30_HALMA

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Protein

50S ribosomal protein L30P

Gene

rpl30p

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

This is one of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains.

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-KW
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciHMAR272569:GJDH-1447-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L30PUniRule annotation
Alternative name(s):
Hl16
Hl20
Hmal30
Gene namesi
Name:rpl30pUniRule annotation
Ordered Locus Names:rrnAC1591
OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Taxonomic identifieri272569 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloarcula
ProteomesiUP000001169: Chromosome I

Subcellular locationi

GO - Cellular componenti

  1. large ribosomal subunit Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 15415450S ribosomal protein L30PPRO_0000104622Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Binds 5S rRNA.2 PublicationsUniRule annotation

Protein-protein interaction databases

STRINGi272569.rrnAC1591.

Structurei

Secondary structure

1
154
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi2 – 65
Helixi15 – 239
Beta strandi31 – 355
Helixi39 – 479
Helixi49 – 513
Beta strandi52 – 554
Helixi59 – 6911
Beta strandi72 – 754
Helixi81 – 877
Beta strandi88 – 925
Helixi93 – 1019
Helixi108 – 1103
Beta strandi114 – 1174
Beta strandi128 – 1314
Helixi132 – 1343
Beta strandi137 – 1404
Helixi143 – 15210

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1FFKX-ray2.40T1-154[»]
1JJ2X-ray2.40V1-154[»]
1K73X-ray3.01X1-154[»]
1K8AX-ray3.00X1-154[»]
1K9MX-ray3.00X1-154[»]
1KC8X-ray3.01X1-154[»]
1KD1X-ray3.00X1-154[»]
1KQSX-ray3.10V1-154[»]
1M1KX-ray3.20X1-154[»]
1M90X-ray2.80X1-154[»]
1N8RX-ray3.00X1-154[»]
1NJIX-ray3.00X1-154[»]
1Q7YX-ray3.20X1-154[»]
1Q81X-ray2.95X1-154[»]
1Q82X-ray2.98X1-154[»]
1Q86X-ray3.00X1-154[»]
1QVFX-ray3.10V1-154[»]
1QVGX-ray2.90V1-154[»]
1S72X-ray2.40W1-154[»]
1VQ4X-ray2.70W1-154[»]
1VQ5X-ray2.60W1-154[»]
1VQ6X-ray2.70W1-154[»]
1VQ7X-ray2.50W1-154[»]
1VQ8X-ray2.20W1-154[»]
1VQ9X-ray2.40W1-154[»]
1VQKX-ray2.30W1-154[»]
1VQLX-ray2.30W1-154[»]
1VQMX-ray2.30W1-154[»]
1VQNX-ray2.40W1-154[»]
1VQOX-ray2.20W1-154[»]
1VQPX-ray2.25W1-154[»]
1W2BX-ray3.50V1-154[»]
1YHQX-ray2.40W1-154[»]
1YI2X-ray2.65W1-154[»]
1YIJX-ray2.60W1-154[»]
1YITX-ray2.80W1-154[»]
1YJ9X-ray2.90W1-154[»]
1YJNX-ray3.00W1-154[»]
1YJWX-ray2.90W1-154[»]
2OTJX-ray2.90W1-154[»]
2OTLX-ray2.70W1-154[»]
2QA4X-ray3.00W1-154[»]
2QEXX-ray2.90W1-154[»]
3CC2X-ray2.40W1-154[»]
3CC4X-ray2.70W1-154[»]
3CC7X-ray2.70W1-154[»]
3CCEX-ray2.75W1-154[»]
3CCJX-ray2.70W1-154[»]
3CCLX-ray2.90W1-154[»]
3CCMX-ray2.55W1-154[»]
3CCQX-ray2.90W1-154[»]
3CCRX-ray3.00W1-154[»]
3CCSX-ray2.95W1-154[»]
3CCUX-ray2.80W1-154[»]
3CCVX-ray2.90W1-154[»]
3CD6X-ray2.75W1-154[»]
3CMAX-ray2.80W1-154[»]
3CMEX-ray2.95W1-154[»]
3CPWX-ray2.70V1-154[»]
3CXCX-ray3.00V1-154[»]
3G4SX-ray3.20W1-154[»]
3G6EX-ray2.70W1-154[»]
3G71X-ray2.85W1-154[»]
3I55X-ray3.11W1-154[»]
3I56X-ray2.90W1-154[»]
3OW2X-ray2.70V1-154[»]
4ADXelectron microscopy6.60W1-154[»]
4HUBX-ray2.40W1-154[»]
ProteinModelPortaliP14121.
SMRiP14121. Positions 1-154.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP14121.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L30P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1841.
HOGENOMiHOG000170918.
KOiK02907.
OMAiAIEMESA.

Family and domain databases

Gene3Di1.10.15.30. 1 hit.
3.30.1390.20. 2 hits.
HAMAPiMF_01371_A. Ribosomal_L30_A.
InterProiIPR005997. Ribosomal_L30_arc.
IPR023106. Ribosomal_L30_central_dom_arc.
IPR018038. Ribosomal_L30_CS.
IPR016082. Ribosomal_L30_ferredoxin-like.
[Graphical view]
PfamiPF00327. Ribosomal_L30. 1 hit.
[Graphical view]
SUPFAMiSSF55129. SSF55129. 1 hit.
TIGRFAMsiTIGR01309. L30P_arch. 1 hit.
PROSITEiPS00634. RIBOSOMAL_L30. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P14121-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHALVQLRGE VNMHTDIQDT LEMLNIHHVN HCTLVPETDA YRGMVAKVND
60 70 80 90 100
FVAFGEPSQE TLETVLATRA EPLEGDADVD DEWVAEHTDY DDISGLAFAL
110 120 130 140 150
LSEETTLREQ GLSPTLRLHP PRGGHDGVKH PVKEGGQLGK HDTEGIDDLL

EAMR
Length:154
Mass (Da):17,042
Last modified:August 1, 1992 - v2
Checksum:iED673F036E974C14
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti83 – 831W → L AA sequence (PubMed:2591382)Curated
Sequence conflicti148 – 1481Missing AA sequence (PubMed:2591382)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X58395 Genomic DNA. Translation: CAA41292.1.
AY596297 Genomic DNA. Translation: AAV46509.1.
PIRiS16543. R5HS30.
RefSeqiYP_136215.1. NC_006396.1.

Genome annotation databases

EnsemblBacteriaiAAV46509; AAV46509; rrnAC1591.
GeneIDi3127531.
KEGGihma:rrnAC1591.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X58395 Genomic DNA. Translation: CAA41292.1 .
AY596297 Genomic DNA. Translation: AAV46509.1 .
PIRi S16543. R5HS30.
RefSeqi YP_136215.1. NC_006396.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1FFK X-ray 2.40 T 1-154 [» ]
1JJ2 X-ray 2.40 V 1-154 [» ]
1K73 X-ray 3.01 X 1-154 [» ]
1K8A X-ray 3.00 X 1-154 [» ]
1K9M X-ray 3.00 X 1-154 [» ]
1KC8 X-ray 3.01 X 1-154 [» ]
1KD1 X-ray 3.00 X 1-154 [» ]
1KQS X-ray 3.10 V 1-154 [» ]
1M1K X-ray 3.20 X 1-154 [» ]
1M90 X-ray 2.80 X 1-154 [» ]
1N8R X-ray 3.00 X 1-154 [» ]
1NJI X-ray 3.00 X 1-154 [» ]
1Q7Y X-ray 3.20 X 1-154 [» ]
1Q81 X-ray 2.95 X 1-154 [» ]
1Q82 X-ray 2.98 X 1-154 [» ]
1Q86 X-ray 3.00 X 1-154 [» ]
1QVF X-ray 3.10 V 1-154 [» ]
1QVG X-ray 2.90 V 1-154 [» ]
1S72 X-ray 2.40 W 1-154 [» ]
1VQ4 X-ray 2.70 W 1-154 [» ]
1VQ5 X-ray 2.60 W 1-154 [» ]
1VQ6 X-ray 2.70 W 1-154 [» ]
1VQ7 X-ray 2.50 W 1-154 [» ]
1VQ8 X-ray 2.20 W 1-154 [» ]
1VQ9 X-ray 2.40 W 1-154 [» ]
1VQK X-ray 2.30 W 1-154 [» ]
1VQL X-ray 2.30 W 1-154 [» ]
1VQM X-ray 2.30 W 1-154 [» ]
1VQN X-ray 2.40 W 1-154 [» ]
1VQO X-ray 2.20 W 1-154 [» ]
1VQP X-ray 2.25 W 1-154 [» ]
1W2B X-ray 3.50 V 1-154 [» ]
1YHQ X-ray 2.40 W 1-154 [» ]
1YI2 X-ray 2.65 W 1-154 [» ]
1YIJ X-ray 2.60 W 1-154 [» ]
1YIT X-ray 2.80 W 1-154 [» ]
1YJ9 X-ray 2.90 W 1-154 [» ]
1YJN X-ray 3.00 W 1-154 [» ]
1YJW X-ray 2.90 W 1-154 [» ]
2OTJ X-ray 2.90 W 1-154 [» ]
2OTL X-ray 2.70 W 1-154 [» ]
2QA4 X-ray 3.00 W 1-154 [» ]
2QEX X-ray 2.90 W 1-154 [» ]
3CC2 X-ray 2.40 W 1-154 [» ]
3CC4 X-ray 2.70 W 1-154 [» ]
3CC7 X-ray 2.70 W 1-154 [» ]
3CCE X-ray 2.75 W 1-154 [» ]
3CCJ X-ray 2.70 W 1-154 [» ]
3CCL X-ray 2.90 W 1-154 [» ]
3CCM X-ray 2.55 W 1-154 [» ]
3CCQ X-ray 2.90 W 1-154 [» ]
3CCR X-ray 3.00 W 1-154 [» ]
3CCS X-ray 2.95 W 1-154 [» ]
3CCU X-ray 2.80 W 1-154 [» ]
3CCV X-ray 2.90 W 1-154 [» ]
3CD6 X-ray 2.75 W 1-154 [» ]
3CMA X-ray 2.80 W 1-154 [» ]
3CME X-ray 2.95 W 1-154 [» ]
3CPW X-ray 2.70 V 1-154 [» ]
3CXC X-ray 3.00 V 1-154 [» ]
3G4S X-ray 3.20 W 1-154 [» ]
3G6E X-ray 2.70 W 1-154 [» ]
3G71 X-ray 2.85 W 1-154 [» ]
3I55 X-ray 3.11 W 1-154 [» ]
3I56 X-ray 2.90 W 1-154 [» ]
3OW2 X-ray 2.70 V 1-154 [» ]
4ADX electron microscopy 6.60 W 1-154 [» ]
4HUB X-ray 2.40 W 1-154 [» ]
ProteinModelPortali P14121.
SMRi P14121. Positions 1-154.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272569.rrnAC1591.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAV46509 ; AAV46509 ; rrnAC1591 .
GeneIDi 3127531.
KEGGi hma:rrnAC1591.

Phylogenomic databases

eggNOGi COG1841.
HOGENOMi HOG000170918.
KOi K02907.
OMAi AIEMESA.

Enzyme and pathway databases

BioCyci HMAR272569:GJDH-1447-MONOMER.

Miscellaneous databases

EvolutionaryTracei P14121.

Family and domain databases

Gene3Di 1.10.15.30. 1 hit.
3.30.1390.20. 2 hits.
HAMAPi MF_01371_A. Ribosomal_L30_A.
InterProi IPR005997. Ribosomal_L30_arc.
IPR023106. Ribosomal_L30_central_dom_arc.
IPR018038. Ribosomal_L30_CS.
IPR016082. Ribosomal_L30_ferredoxin-like.
[Graphical view ]
Pfami PF00327. Ribosomal_L30. 1 hit.
[Graphical view ]
SUPFAMi SSF55129. SSF55129. 1 hit.
TIGRFAMsi TIGR01309. L30P_arch. 1 hit.
PROSITEi PS00634. RIBOSOMAL_L30. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Primary structures of five ribosomal proteins from the archaebacterium Halobacterium marismortui and their structural relationships to eubacterial and eukaryotic ribosomal proteins."
    Hatakeyama T., Kaufmann F., Schroeter B., Hatakeyama T.
    Eur. J. Biochem. 185:685-693(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.
  2. "Organization and nucleotide sequence of ten ribosomal protein genes from the region equivalent to the spectinomycin operon in the archaebacterium Halobacterium marismortui."
    Scholzen T., Arndt E.
    Mol. Gen. Genet. 228:70-80(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
  4. "Extended N-terminal sequencing of proteins of archaebacterial ribosomes blotted from two-dimensional gels onto glass fiber and poly(vinylidene difluoride) membrane."
    Walsh M.J., McDougall J., Wittmann-Liebold B.
    Biochemistry 27:6867-6876(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 1-30.
  5. "The complete atomic structure of the large ribosomal subunit at 2.4 A resolution."
    Ban N., Nissen P., Hansen J., Moore P.B., Steitz T.A.
    Science 289:905-920(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF THE 50S SUBUNIT.
    Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
  6. "The structural basis of ribosome activity in peptide bond synthesis."
    Nissen P., Hansen J., Ban N., Moore P.B., Steitz T.A.
    Science 289:920-930(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 50S SUBUNIT.
    Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
  7. "A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits."
    Schmeing T.M., Seila A.C., Hansen J.L., Freeborn B., Soukup J.K., Scaringe S.A., Strobel S.A., Moore P.B., Steitz T.A.
    Nat. Struct. Biol. 9:225-230(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS) OF THE 50S SUBUNIT.
    Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
  8. "The kink-turn: a new RNA secondary structure motif."
    Klein D.J., Schmeing T.M., Moore P.B., Steitz T.A.
    EMBO J. 20:4214-4221(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF THE 50S SUBUNIT.
    Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
  9. "The structures of four macrolide antibiotics bound to the large ribosomal subunit."
    Hansen J.L., Ippolito J.A., Ban N., Nissen P., Moore P.B., Steitz T.A.
    Mol. Cell 10:117-128(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH FOUR MACROLIDE ANTIBIOTICS.
    Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
  10. Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF THE 50S SUBUNIT.
    Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
  11. "Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit."
    Hansen J.L., Moore P.B., Steitz T.A.
    J. Mol. Biol. 330:1061-1075(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH FIVE ANTIBIOTICS AT THE PEPTIDYL TRANSFERASE CENTER.
    Strain: ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809.
  12. "Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit."
    Schmeing T.M., Moore P.B., Steitz T.A.
    RNA 9:1345-1352(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF THE 50S SUBUNIT WITH TWO DIFFERENT E SITE SUBSTRATES.
  13. "Revisiting the Haloarcula marismortui 50S ribosomal subunit model."
    Gabdulkhakov A., Nikonov S., Garber M.
    Acta Crystallogr. D 69:997-1004(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF THE 50S SUBUNIT.

Entry informationi

Entry nameiRL30_HALMA
AccessioniPrimary (citable) accession number: P14121
Secondary accession number(s): Q5V1U3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: August 1, 1992
Last modified: October 1, 2014
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3