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P14120 (RL30_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 139. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
60S ribosomal protein L30
Alternative name(s):
L32
RP73
YL38
Gene names
Name:RPL30
Synonyms:RPL32
Ordered Locus Names:YGL030W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length105 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.4

Subcellular location

Cytoplasm By similarity.

Miscellaneous

Present with 59300 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the ribosomal protein L30e family.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

URN1Q065251EBI-15333,EBI-35138

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.1 Ref.5
Chain2 – 10510460S ribosomal protein L30
PRO_0000146143

Secondary structure

................ 105
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P14120 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 963C973A02E9C8E5

FASTA10511,415
        10         20         30         40         50         60 
MAPVKSQESI NQKLALVIKS GKYTLGYKST VKSLRQGKSK LIIIAANTPV LRKSELEYYA 

        70         80         90        100 
MLSKTKVYYF QGGNNELGTA VGKLFRVGVV SILEAGDSDI LTTLA 

« Hide

References

« Hide 'large scale' references
[1]"The yeast ribosomal protein L32 and its gene."
Dabeva M.D., Warner J.R.
J. Biol. Chem. 262:16055-16059(1987) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 2-8.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. expand/collapse author list , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."
Planta R.J., Mager W.H.
Yeast 14:471-477(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NOMENCLATURE, SUBUNIT.
[5]"The action of N-terminal acetyltransferases on yeast ribosomal proteins."
Arnold R.J., Polevoda B., Reilly J.P., Sherman F.
J. Biol. Chem. 274:37035-37040(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: CLEAVAGE OF INITIATOR METHIONINE.
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[7]"Sites of ubiquitin attachment in Saccharomyces cerevisiae."
Starita L.M., Lo R.S., Eng J.K., von Haller P.D., Fields S.
Proteomics 12:236-240(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[8]"A novel loop-loop recognition motif in the yeast ribosomal protein L30 autoregulatory RNA complex."
Mao H., White S.A., Williamson J.R.
Nat. Struct. Biol. 6:1139-1147(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY NMR.
[9]"Inherent protein structural flexibility at the RNA-binding interface of L30e."
Chao J.A., Prasad G.S., White S.A., Stout C.D., Williamson J.R.
J. Mol. Biol. 326:999-1004(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.31 ANGSTROMS).
[10]"Joint X-ray and NMR refinement of the yeast L30e-mRNA complex."
Chao J.A., Williamson J.R.
Structure 12:1165-1176(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.24 ANGSTROMS) IN COMPLEX WITH MRNA.
[11]"Crystal structure of the eukaryotic ribosome."
Ben-Shem A., Jenner L., Yusupova G., Yusupov M.
Science 330:1203-1209(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS) OF 80S RIBOSOME.
[12]"The structure of the eukaryotic ribosome at 3.0 A resolution."
Ben-Shem A., Garreau de Loubresse N., Melnikov S., Jenner L., Yusupova G., Yusupov M.
Science 334:1524-1529(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 80S RIBOSOME.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
J03457 Genomic DNA. Translation: AAA35005.1.
Z72552 Genomic DNA. Translation: CAA96731.1.
BK006941 Genomic DNA. Translation: DAA08069.1.
PIRR6BY30. A29779.
RefSeqNP_011485.1. NM_001180895.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1CK2NMR-A2-105[»]
1CN7NMR-A2-105[»]
1NMUX-ray2.31B/D2-105[»]
1T0KX-ray3.24B1-105[»]
3IZSelectron microscopy-f1-105[»]
3J65electron microscopy8.70b1-105[»]
3O58X-ray4.00Z1-105[»]
3O5HX-ray4.00Z1-105[»]
3U5EX-ray3.00c1-105[»]
3U5IX-ray3.00c1-105[»]
4B6Aelectron microscopy8.10c1-105[»]
4BYNelectron microscopy4.30c2-105[»]
4BYUelectron microscopy6.60c2-105[»]
ProteinModelPortalP14120.
SMRP14120. Positions 2-105.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33216. 142 interactions.
DIPDIP-1891N.
IntActP14120. 88 interactions.
MINTMINT-406716.
STRING4932.YGL030W.

Proteomic databases

MaxQBP14120.
PaxDbP14120.
PeptideAtlasP14120.
PRIDEP14120.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYGL030W; YGL030W; YGL030W.
GeneID852853.
KEGGsce:YGL030W.

Organism-specific databases

SGDS000002998. RPL30.

Phylogenomic databases

eggNOGCOG1911.
GeneTreeENSGT00390000012138.
HOGENOMHOG000055224.
KOK02908.
OMAMRNGKAK.
OrthoDBEOG76MKNV.

Enzyme and pathway databases

BioCycYEAST:G3O-30546-MONOMER.

Gene expression databases

GenevestigatorP14120.

Family and domain databases

Gene3D3.30.1330.30. 1 hit.
InterProIPR029064. L30e-like.
IPR000231. Ribosomal_L30e.
IPR022991. Ribosomal_L30e_CS.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
[Graphical view]
PANTHERPTHR11449. PTHR11449. 1 hit.
PfamPF01248. Ribosomal_L7Ae. 1 hit.
[Graphical view]
SUPFAMSSF55315. SSF55315. 1 hit.
PROSITEPS00709. RIBOSOMAL_L30E_1. 1 hit.
PS00993. RIBOSOMAL_L30E_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP14120.
NextBio972449.
PROP14120.

Entry information

Entry nameRL30_YEAST
AccessionPrimary (citable) accession number: P14120
Secondary accession number(s): D6VUA8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 23, 2007
Last modified: June 11, 2014
This is version 139 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VII

Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references