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Protein

60S ribosomal protein L27a

Gene

Rpl27a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L27a
Alternative name(s):
L29
Gene namesi
Name:Rpl27a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1347076. Rpl27a.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001048802 – 14860S ribosomal protein L27aAdd BLAST147

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei39(3S)-3-hydroxyhistidineBy similarity1
Modified residuei47N6-acetyllysineBy similarity1
Modified residuei55N6-acetyllysineBy similarity1
Modified residuei68PhosphoserineCombined sources1
Modified residuei110N6-acetyllysineBy similarity1

Post-translational modificationi

Hydroxylated on His-39 by MINA.By similarity

Keywords - PTMi

Acetylation, Hydroxylation, Phosphoprotein

Proteomic databases

EPDiP14115.
MaxQBiP14115.
PaxDbiP14115.
PeptideAtlasiP14115.
PRIDEiP14115.

PTM databases

iPTMnetiP14115.
PhosphoSitePlusiP14115.
SwissPalmiP14115.

Expressioni

Gene expression databases

BgeeiENSMUSG00000046364.
CleanExiMM_RPL27A.
ExpressionAtlasiP14115. baseline and differential.
GenevisibleiP14115. MM.

Interactioni

Protein-protein interaction databases

BioGridi205001. 3 interactors.
IntActiP14115. 4 interactors.
MINTiMINT-1866600.
STRINGi10090.ENSMUSP00000123410.

Structurei

3D structure databases

ProteinModelPortaliP14115.
SMRiP14115.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L15P family.Curated

Phylogenomic databases

eggNOGiKOG1742. Eukaryota.
COG0200. LUCA.
GeneTreeiENSGT00390000005534.
HOGENOMiHOG000231263.
HOVERGENiHBG054587.
InParanoidiP14115.
KOiK02900.
OMAiRHGYAKV.
OrthoDBiEOG091G0TQF.
PhylomeDBiP14115.
TreeFamiTF313742.

Family and domain databases

HAMAPiMF_01341. Ribosomal_L15. 1 hit.
InterProiIPR030878. Ribosomal_L15.
IPR001196. Ribosomal_L15_CS.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view]
PfamiPF00828. Ribosomal_L27A. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.
PROSITEiPS00475. RIBOSOMAL_L15. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P14115-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSRLRKTRK LRGHVSHGHG RIGKHRKHPG GRGNAGGMHH HRINFDKYHP
60 70 80 90 100
GYFGKVGMRH YHLKRNQSFC PTVNLDKLWT LVSEQTRVNA AKNKTGVAPI
110 120 130 140
IDVVRSGYYK VLGKGKLPKQ PVIVKAKFFS RRAEEKIKGV GGACVLVA
Length:148
Mass (Da):16,605
Last modified:October 5, 2010 - v5
Checksum:iD6E11FA50E24D206
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti30G → S in CAA28678 (PubMed:2434927).Curated1
Sequence conflicti78L → P in CAA28678 (PubMed:2434927).Curated1
Sequence conflicti78L → P in BAA77362 (PubMed:10449908).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X05021 mRNA. Translation: CAA28678.1.
AB020237 Genomic DNA. Translation: BAA77362.1.
AJ307670 Genomic DNA. Translation: CAC38113.1.
AK007837 mRNA. Translation: BAB25295.1.
AK008531 mRNA. Translation: BAB25724.1.
AK010286 mRNA. Translation: BAB26822.1.
AK150907 mRNA. Translation: BAE29949.1.
AK167792 mRNA. Translation: BAE39822.1.
AK167915 mRNA. Translation: BAE39922.1.
CH466531 Genomic DNA. Translation: EDL16941.1.
BC056958 mRNA. Translation: AAH56958.1.
BC081430 mRNA. Translation: AAH81430.1.
BC086939 mRNA. Translation: AAH86939.1.
CCDSiCCDS40083.1.
PIRiS11557. R5MS27.
RefSeqiNP_036105.2. NM_011975.3.
UniGeneiMm.305750.

Genome annotation databases

EnsembliENSMUST00000143107; ENSMUSP00000123410; ENSMUSG00000046364.
GeneIDi26451.
KEGGimmu:26451.
UCSCiuc009jdr.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X05021 mRNA. Translation: CAA28678.1.
AB020237 Genomic DNA. Translation: BAA77362.1.
AJ307670 Genomic DNA. Translation: CAC38113.1.
AK007837 mRNA. Translation: BAB25295.1.
AK008531 mRNA. Translation: BAB25724.1.
AK010286 mRNA. Translation: BAB26822.1.
AK150907 mRNA. Translation: BAE29949.1.
AK167792 mRNA. Translation: BAE39822.1.
AK167915 mRNA. Translation: BAE39922.1.
CH466531 Genomic DNA. Translation: EDL16941.1.
BC056958 mRNA. Translation: AAH56958.1.
BC081430 mRNA. Translation: AAH81430.1.
BC086939 mRNA. Translation: AAH86939.1.
CCDSiCCDS40083.1.
PIRiS11557. R5MS27.
RefSeqiNP_036105.2. NM_011975.3.
UniGeneiMm.305750.

3D structure databases

ProteinModelPortaliP14115.
SMRiP14115.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi205001. 3 interactors.
IntActiP14115. 4 interactors.
MINTiMINT-1866600.
STRINGi10090.ENSMUSP00000123410.

PTM databases

iPTMnetiP14115.
PhosphoSitePlusiP14115.
SwissPalmiP14115.

Proteomic databases

EPDiP14115.
MaxQBiP14115.
PaxDbiP14115.
PeptideAtlasiP14115.
PRIDEiP14115.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000143107; ENSMUSP00000123410; ENSMUSG00000046364.
GeneIDi26451.
KEGGimmu:26451.
UCSCiuc009jdr.1. mouse.

Organism-specific databases

CTDi6157.
MGIiMGI:1347076. Rpl27a.

Phylogenomic databases

eggNOGiKOG1742. Eukaryota.
COG0200. LUCA.
GeneTreeiENSGT00390000005534.
HOGENOMiHOG000231263.
HOVERGENiHBG054587.
InParanoidiP14115.
KOiK02900.
OMAiRHGYAKV.
OrthoDBiEOG091G0TQF.
PhylomeDBiP14115.
TreeFamiTF313742.

Miscellaneous databases

PROiP14115.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000046364.
CleanExiMM_RPL27A.
ExpressionAtlasiP14115. baseline and differential.
GenevisibleiP14115. MM.

Family and domain databases

HAMAPiMF_01341. Ribosomal_L15. 1 hit.
InterProiIPR030878. Ribosomal_L15.
IPR001196. Ribosomal_L15_CS.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view]
PfamiPF00828. Ribosomal_L27A. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.
PROSITEiPS00475. RIBOSOMAL_L15. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL27A_MOUSE
AccessioniPrimary (citable) accession number: P14115
Secondary accession number(s): Q9CQ16, Q9R1X6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: October 5, 2010
Last modified: November 2, 2016
This is version 121 of the entry and version 5 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.