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P14058 (COX3_SCHCO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismSchizophyllum commune (Split gill fungus)
Taxonomic identifier5334 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesSchizophyllaceaeSchizophyllum

Protein attributes

Sequence length268 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 268268Cytochrome c oxidase subunit 3
PRO_0000183850

Regions

Transmembrane19 – 3921Helical; Potential
Transmembrane49 – 6921Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane124 – 14421Helical; Potential
Transmembrane165 – 18521Helical; Potential
Transmembrane202 – 22221Helical; Potential
Transmembrane245 – 26521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P14058 [UniParc].

Last modified February 1, 1996. Version 2.
Checksum: B90B97B8DAE4265A

FASTA26829,922
        10         20         30         40         50         60 
MTSIKFYQSF SAHLVQHSPW PILVSFSLFN LAIGTVLTMH GYSHSSTTFD LGLAVTVGSI 

        70         80         90        100        110        120 
LLWTRDIVIE GSFLGDHTKQ VQEGLIIGFI LFIISEVFAF ISVFWAYFHS ALSPAVELGS 

       130        140        150        160        170        180 
TWPPVGIIPL DTFSLPLFNT IILLSSGAFV TYGHHAIFSG KRLDSIIGLF LTVALALIFS 

       190        200        210        220        230        240 
YFQAFEYIHA GFSMSDSVFG TVFFASTGLH GIHVMLGTLF LFVSFLRQVN YQTTKEHNIG 

       250        260 
LETSILYWHF VDLVWLFLFL VVYFWGGA 

« Hide

References

[1]"Nucleotide base sequence of the mitochondrial COIII gene of Schizophyllum commune."
Phelps L.G., Burke J.M., Ullrich R.C., Novotny C.P.
Curr. Genet. 14:401-403(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M36270 Genomic DNA. Translation: AAA32065.2.
PIRS07557.

3D structure databases

ProteinModelPortalP14058.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_SCHCO
AccessionPrimary (citable) accession number: P14058
Entry history
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: February 1, 1996
Last modified: April 16, 2014
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families