Reviewed,
UniProtKB/Swiss-Prot P14012 (ARGI_AGRT5)
Last modified
November 3, 2009.
Version 77.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Arginase EC=3.5.3.1 | ||||||||
| Gene names |
| ||||||||
| Encoded on | Plasmid pTiC58 | ||||||||
| Organism | Agrobacterium tumefaciens (strain C58 / ATCC 33970) [Complete proteome] [HAMAP] | ||||||||
| Taxonomic identifier | 176299 [NCBI] | ||||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium |
Protein attributes
| Sequence length | 324 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | L-arginine + H2O = L-ornithine + urea. |
| Cofactor | Binds 2 manganese ions per subunit By similarity. |
| Pathway | |
| Subunit structure | Homohexamer Probable. |
| Induction | By nopaline. But not by L-arginine or L-ornithine. |
| Sequence similarities | Belongs to the arginase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Arginine metabolism |
| Ligand | Manganese Metal-binding |
| Molecular function | Hydrolase |
| Technical term | Complete proteome Plasmid |
| Gene Ontology (GO) | |
| Biological process | arginine metabolic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | arginase activity Inferred from electronic annotation. Source: EC manganese ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 324 | 324 | Arginase | PRO_0000173712 | |||||
Regions | |||||||||
| Region | 144 – 148 | 5 | Substrate binding By similarity | ||||||
| Region | 155 – 157 | 3 | Substrate binding By similarity | ||||||
Sites | |||||||||
| Metal binding | 115 | 1 | Manganese 1 By similarity | ||||||
| Metal binding | 142 | 1 | Manganese 1 By similarity | ||||||
| Metal binding | 142 | 1 | Manganese 2 By similarity | ||||||
| Metal binding | 144 | 1 | Manganese 2 By similarity | ||||||
| Metal binding | 146 | 1 | Manganese 1 By similarity | ||||||
| Metal binding | 244 | 1 | Manganese 1 By similarity | ||||||
| Metal binding | 244 | 1 | Manganese 2 By similarity | ||||||
| Metal binding | 246 | 1 | Manganese 2 By similarity | ||||||
| Binding site | 196 | 1 | Substrate By similarity | ||||||
| Binding site | 289 | 1 | Substrate By similarity | ||||||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| X15884 Genomic DNA. Translation: CAA33894.1. Z30316 Genomic DNA. Translation: CAA82964.1. AE007871 Genomic DNA. Translation: AAK90976.2. | |
| PIR | AH3229. S06118. |
| RefSeq | NP_053430.1. NP_396535.2. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1CEV based on UniProtKB P53608. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | P14012. |
Genome annotation databases | |
| GeneID | 1137341. 1224186. |
| GenomeReviews | Gene locus Atu6018 in contig AE007871_GR. |
| KEGG | atc:AGR_pTi_56. atu:Atu6018. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | P14012. |
| OMA | IDARSAP. |
Enzyme and pathway databases | |
| BioCyc | MetaCyc:MON-11552. |
Family and domain databases | |
| InterPro | IPR005924. Arginase. IPR014033. Arginase_sub. IPR006035. Ureohydrolase. [Graphical view] |
| Gene3D | G3DSA:3.40.800.10. Ureohydrolase. 1 hit. |
| PANTHER | PTHR11358:SF2. Arginase_sub. 1 hit. PTHR11358. Ureohydrolase. 1 hit. |
| Pfam | PF00491. Arginase. 1 hit. [Graphical view] |
| PRINTS | PR00116. ARGINASE. |
| TIGRFAMs | TIGR01229. rocF_arginase. 1 hit. |
| PROSITE | PS01053. ARGINASE_1. 1 hit. PS51409. ARGINASE_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ARGI_AGRT5 | ||||||||
| Accession | Primary (citable) accession number: P14012 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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