Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P14004 (ALL5_DERPT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mite allergen Der p 5
Alternative name(s):
Allergen Der P V
IgE-binding allergen
Allergen=Der p 5
Gene names
Name:DERP5
OrganismDermatophagoides pteronyssinus (European house dust mite)
Taxonomic identifier6956 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataPsoroptidiaAnalgoideaPyroglyphidaeDermatophagoidinaeDermatophagoides

Protein attributes

Sequence length132 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Allergenic properties

Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis. Binds to IgE.

Sequence similarities

Belongs to the mite group 5 allergen family.

Sequence caution

The sequence CAA35692.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   DiseaseAllergen
   Technical term3D-structure
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 132132Mite allergen Der p 5
PRO_0000151066

Natural variations

Natural variant611E → A.

Secondary structure

....... 132
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P14004 [UniParc].

Last modified February 1, 1996. Version 2.
Checksum: 3C840C3C26707C05

FASTA13215,615
        10         20         30         40         50         60 
MKFIIAFFVA TLAVMTVSGE DKKHDYQNEF DFLLMERIHE QIKKGELALF YLQEQINHFE 

        70         80         90        100        110        120 
EKPTKEMKDK IVAEMDTIIA MIDGVRGVLD RLMQRKDLDI FEQYNLEMAK KSGDILERDL 

       130 
KKEEARVKKI EV 

« Hide

References

[1]"Characterization of Der p V allergen, cDNA analysis, and IgE-mediated reactivity to the recombinant protein."
Lin K.L., Hsieh K.H., Thomas W.R., Chiang B.L., Chua K.Y.
J. Allergy Clin. Immunol. 94:989-996(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Cloning and sequencing of a cDNA expressing a recombinant house dust mite protein that binds human IgE and corresponds to an important low molecular weight allergen."
Tovey E.R., Johnson M.C., Roche A.L., Cobon G.S., Baldo B.A.
J. Exp. Med. 170:1457-1462(1989) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[3]Cobon G.S.
Submitted (FEB-1990) to the EMBL/GenBank/DDBJ databases
Cited for: SEQUENCE REVISION TO 132.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
S76337 mRNA. Translation: AAB32841.1.
S76340 mRNA. Translation: AAB32842.1.
X17699 mRNA. Translation: CAA35692.1. Different initiation.
PIRS06734.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3MQ1X-ray2.80A/B/C/D/E/F34-132[»]
ProteinModelPortalP14004.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome319. Der p 5.
3265. Der p 5.0101.
3266. Der p 5.0102.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR020306. Mite_allergen_group-5/21.
[Graphical view]
PfamPF11642. Blo-t-5. 1 hit.
[Graphical view]
ProDomPD081736. Mite_allergen_group_5/21. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Other

EvolutionaryTraceP14004.

Entry information

Entry nameALL5_DERPT
AccessionPrimary (citable) accession number: P14004
Entry history
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: February 1, 1996
Last modified: April 3, 2013
This is version 55 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Allergens

Nomenclature of allergens and list of entries