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P13997 (TRPF_KLULA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-(5'-phosphoribosyl)anthranilate isomerase

Short name=PRAI
EC=5.3.1.24
Gene names
Name:TRP1
Ordered Locus Names:KLLA0E17699g
OrganismKluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) [Complete proteome]
Taxonomic identifier284590 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKluyveromyces

Protein attributes

Sequence length210 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135

Sequence similarities

Belongs to the TrpF family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
Tryptophan biosynthesis
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtryptophan biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionphosphoribosylanthranilate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 210210N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135
PRO_0000154333

Sequences

Sequence LengthMass (Da)Tools
P13997 [UniParc].

Last modified January 1, 1990. Version 1.
Checksum: 0F406A05E83CFA95

FASTA21022,880
        10         20         30         40         50         60 
MLVKVCGLQT VEAAKTAVDD GADYLGIICV PGRKRTIDSS VAKGISTAVH QQENVKGTKL 

        70         80         90        100        110        120 
VGVFRNQSVD DVLQLYHEYN LDVIQLHGDE DIKEYRSLIP SSIPIIKRFQ FPQDCELLLD 

       130        140        150        160        170        180 
LYEHVDNVLT LFDSGEGGTG EKLNWSAISS WSASHPEIKF IIAGGLNPDN VSVAINMLPN 

       190        200        210 
AIGVDVSGGV ETDGIKDLEK VKLFIQQASQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X14230 Genomic DNA. Translation: CAA32445.1.
CR382125 Genomic DNA. Translation: CAG99832.1.
PIRISVKNL. S07893.
RefSeqXP_454745.1. XM_454745.1.

3D structure databases

ProteinModelPortalP13997.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING28985.P13997.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2894278.
KEGGkla:KLLA0E17645g.

Phylogenomic databases

eggNOGCOG0135.
HOGENOMHOG000161598.
KOK01817.
OMAQDYFIAG.
OrthoDBEOG76MKM7.

Enzyme and pathway databases

UniPathwayUPA00035; UER00042.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00135. PRAI.
InterProIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRPF_KLULA
AccessionPrimary (citable) accession number: P13997
Entry history
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: February 19, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways