P13913 (ARY1_CHICK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Arylamine N-acetyltransferase, pineal gland isozyme NAT-10 Short name=Arylamine acetylase EC=2.3.1.5
Organism	Gallus gallus (Chicken) [Reference proteome]
Taxonomic identifier	9031 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Sauropsida › Sauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	290 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	Acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
Sequence similarities	Belongs to the arylamine N-acetyltransferase family.

Ontologies

Keywords
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	arylamine N-acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 290	290	Arylamine N-acetyltransferase, pineal gland isozyme NAT-10		PRO_0000107901
Sites
	Active site	68	1	Acyl-thioester intermediate By similarity
	Active site	107	1	By similarity
	Active site	122	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P13913 [UniParc]. Last modified January 1, 1990. Version 1. Checksum: CBED93184E5F137C	FASTA	290	33,925
	10 20 30 40 50 60 MNLEEYFART GYKGSLENQD LETLTDIFQH HIRAVPFENL SIHCGEKITL ELEHVYNKIV 70 80 90 100 110 120 HKKRGGWCME NNQLLGWVLK CLGYDTSFLG AYVFNPHENA YATIMTHLLV KVVIEGKAYI 130 140 150 160 170 180 VDAGFGVSYQ MWQPMELVSG KDQPQAPGIF RFTEKNAIWY LEKMRRKQYI PNQNFSNSDL 190 200 210 220 230 240 LEKKDCRKVY MFSLEPRTVE DFCFQCTYLQ TSPDSLFTKK SICTLQTTDG FRALIGWTLT 250 260 270 280 290 ETKYNYKENM DLVEFITLKD EEVEKTLKDK FNITLERKLV PINVKGFYTI

References

[1]	"Two arylamine N-acetyltransferases from chicken pineal gland as identified by cDNA cloning." Ohtomi M., Sasaki M., Deguchi T. Eur. J. Biochem. 185:253-261(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: White leghorn. Tissue: Pineal gland.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X16021 mRNA. Translation: CAA34153.1.
IPI	IPI00596241.
PIR	XYCHY0. S06653.
RefSeq	NP_990671.1. NM_205340.1.
UniGene	Gga.746.
3D structure databases
ProteinModelPortal	P13913.
SMR	P13913. Positions 2-290.
ModBase	Search...
Protein-protein interaction databases
STRING	9031.ENSGALP00000008780.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	396283.
KEGG	gga:396283.
Organism-specific databases
CTD	396283.
Phylogenomic databases
eggNOG	COG2162.
HOGENOM	HOG000205435.
HOVERGEN	HBG000165.
InParanoid	P13913.
KO	K00622.
OrthoDB	EOG46Q6T2.
Family and domain databases
InterPro	IPR001447. Arylamine_N-AcTrfase. [Graphical view]
PANTHER	PTHR11786. PTHR11786. 1 hit.
Pfam	PF00797. Acetyltransf_2. 1 hit. [Graphical view]
PRINTS	PR01543. ANATRNSFRASE.
ProtoNet	Search...
Other
NextBio	20816334.

Entry information

Entry name

ARY1_CHICK

Accession

Primary (citable) accession number: P13913

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 1, 1990
Last sequence update:	January 1, 1990
Last modified:	April 3, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program