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P13747

- HLAE_HUMAN

UniProt

P13747 - HLAE_HUMAN

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Protein
HLA class I histocompatibility antigen, alpha chain E
Gene
HLA-E, HLA-6.2, HLAE
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules.

GO - Molecular functioni

  1. MHC class I protein binding Source: UniProt
  2. peptide antigen binding Source: UniProt
  3. receptor binding Source: RefGenome

GO - Biological processi

  1. antigen processing and presentation of endogenous peptide antigen via MHC class Ib Source: UniProt
  2. antigen processing and presentation of exogenous peptide antigen via MHC class I Source: Reactome
  3. antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent Source: Reactome
  4. antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent Source: Reactome
  5. antigen processing and presentation of peptide antigen via MHC class I Source: Reactome
  6. cytokine-mediated signaling pathway Source: Reactome
  7. innate immune response Source: Reactome
  8. interferon-gamma-mediated signaling pathway Source: Reactome
  9. positive regulation of T cell mediated cytotoxicity Source: InterPro
  10. positive regulation of natural killer cell mediated immunity Source: UniProt
  11. protection from natural killer cell mediated cytotoxicity Source: UniProt
  12. regulation of immune response Source: Reactome
  13. type I interferon signaling pathway Source: Reactome
Complete GO annotation...

Keywords - Biological processi

Immunity

Enzyme and pathway databases

ReactomeiREACT_111168. Endosomal/Vacuolar pathway.
REACT_111178. ER-Phagosome pathway.
REACT_11152. Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.
REACT_147694. DAP12 interactions.
REACT_147814. DAP12 signaling.
REACT_25078. Interferon gamma signaling.
REACT_25162. Interferon alpha/beta signaling.
REACT_75795. Antigen Presentation: Folding, assembly and peptide loading of class I MHC.

Names & Taxonomyi

Protein namesi
Recommended name:
HLA class I histocompatibility antigen, alpha chain E
Alternative name(s):
MHC class I antigen E
Gene namesi
Name:HLA-E
Synonyms:HLA-6.2, HLAE
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:4962. HLA-E.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini22 – 305284Extracellular Reviewed prediction
Add
BLAST
Transmembranei306 – 32924Helical; Reviewed prediction
Add
BLAST
Topological domaini330 – 35829Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. ER to Golgi transport vesicle membrane Source: Reactome
  2. Golgi membrane Source: Reactome
  3. MHC class I protein complex Source: UniProtKB-KW
  4. cell surface Source: UniProt
  5. early endosome membrane Source: Reactome
  6. extracellular vesicular exosome Source: UniProt
  7. integral component of lumenal side of endoplasmic reticulum membrane Source: Reactome
  8. phagocytic vesicle membrane Source: Reactome
  9. plasma membrane Source: Reactome
Complete GO annotation...

Keywords - Cellular componenti

Membrane, MHC I

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35081.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121
Add
BLAST
Chaini22 – 358337HLA class I histocompatibility antigen, alpha chain E
PRO_0000018882Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi107 – 1071N-linked (GlcNAc...)1 Publication
Disulfide bondi122 ↔ 185
Disulfide bondi224 ↔ 280

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MaxQBiP13747.
PaxDbiP13747.
PRIDEiP13747.

PTM databases

PhosphoSiteiP13747.

Expressioni

Gene expression databases

CleanExiHS_HLA-E.
GenevestigatoriP13747.

Organism-specific databases

HPAiCAB024589.
HPA031454.

Interactioni

Subunit structurei

Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin).

Protein-protein interaction databases

BioGridi109378. 6 interactions.
DIPiDIP-32N.
IntActiP13747. 18 interactions.
STRINGi9606.ENSP00000373091.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi24 – 3310
Beta strandi36 – 405
Beta strandi42 – 498
Beta strandi52 – 587
Beta strandi61 – 633
Beta strandi65 – 684
Helixi71 – 733
Helixi78 – 10528
Beta strandi110 – 1123
Beta strandi115 – 12410
Beta strandi128 – 13912
Beta strandi142 – 1476
Beta strandi151 – 1588
Helixi159 – 1613
Helixi162 – 1709
Turni171 – 1733
Helixi174 – 1829
Helixi184 – 19512
Helixi197 – 2004
Beta strandi207 – 2148
Beta strandi216 – 23217
Beta strandi235 – 2395
Turni241 – 2433
Beta strandi249 – 2513
Beta strandi258 – 2603
Beta strandi262 – 27110
Helixi275 – 2773
Beta strandi279 – 2835
Beta strandi287 – 2893
Beta strandi291 – 2933

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1KPRX-ray2.80A/C22-295[»]
1KTLX-ray3.10A/C22-295[»]
1MHEX-ray2.85A/C22-295[»]
2ESVX-ray2.60A23-297[»]
3AM8X-ray2.80A/B22-297[»]
3BZEX-ray2.50A/C/E/G23-295[»]
3BZFX-ray2.50A/C22-297[»]
3CDGX-ray3.40A/C23-295[»]
3CIIX-ray4.41A/D23-295[»]
ProteinModelPortaliP13747.
SMRiP13747. Positions 22-297.

Miscellaneous databases

EvolutionaryTraceiP13747.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini206 – 29489Ig-like C1-type
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni22 – 11190Alpha-1
Add
BLAST
Regioni112 – 20392Alpha-2
Add
BLAST
Regioni204 – 29592Alpha-3
Add
BLAST
Regioni296 – 30510Connecting peptide

Sequence similaritiesi

Belongs to the MHC class I family.

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG329718.
HOVERGENiHBG016709.
InParanoidiP13747.
KOiK06751.
OMAiGPRYSHA.
PhylomeDBiP13747.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P13747-1 [UniParc]FASTAAdd to Basket

« Hide

MVDGTLLLLL SEALALTQTW AGSHSLKYFH TSVSRPGRGE PRFISVGYVD    50
DTQFVRFDND AASPRMVPRA PWMEQEGSEY WDRETRSARD TAQIFRVNLR 100
TLRGYYNQSE AGSHTLQWMH GCELGPDRRF LRGYEQFAYD GKDYLTLNED 150
LRSWTAVDTA AQISEQKSND ASEAEHQRAY LEDTCVEWLH KYLEKGKETL 200
LHLEPPKTHV THHPISDHEA TLRCWALGFY PAEITLTWQQ DGEGHTQDTE 250
LVETRPAGDG TFQKWAAVVV PSGEEQRYTC HVQHEGLPEP VTLRWKPASQ 300
PTIPIVGIIA GLVLLGSVVS GAVVAAVIWR KKSSGGKGGS YSKAEWSDSA 350
QGSESHSL 358
Length:358
Mass (Da):40,157
Last modified:August 29, 2003 - v3
Checksum:i2A211B603591D248
GO

Polymorphismi

The following alleles of E-1 are known: E*01:01, E*0102, E*01:03 and E*01:04. The sequence shown is that of E*01:01.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti98 – 981N → K.
Corresponds to variant rs1059510 [ dbSNP | Ensembl ].
VAR_059510
Natural varianti104 – 1041G → R in allele E*0102.
VAR_004395
Natural varianti128 – 1281R → G in allele E*01:03 and allele E*01:04.
Corresponds to variant rs1264457 [ dbSNP | Ensembl ].
VAR_016651
Natural varianti178 – 1781R → G in allele E*01:04.
Corresponds to variant rs41562314 [ dbSNP | Ensembl ].
VAR_016652

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti10 – 101L → S in AAA52655. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M20022 mRNA. Translation: AAA52655.1.
AJ293263 mRNA. Translation: CAC07212.1.
AJ293264 mRNA. Translation: CAC07213.1.
AF523274 Genomic DNA. Translation: AAM74969.1.
AF523275 Genomic DNA. Translation: AAM74970.1.
AF523276 Genomic DNA. Translation: AAM74971.1.
AF523277 Genomic DNA. Translation: AAM74972.1.
AF523278 Genomic DNA. Translation: AAM74973.1.
AF523279 Genomic DNA. Translation: AAM74974.1.
AF523280 Genomic DNA. Translation: AAM74975.1.
AF523281 Genomic DNA. Translation: AAM74976.1.
AF523282 Genomic DNA. Translation: AAM74977.1.
AF523283 Genomic DNA. Translation: AAM74978.1.
BA000025 Genomic DNA. Translation: BAB63328.1.
BC002578 mRNA. Translation: AAH02578.1.
BC004297 mRNA. Translation: AAH04297.1.
M21533 Genomic DNA. Translation: AAA59835.1.
AY221103 mRNA. Translation: AAO34408.1.
AY216681 mRNA. Translation: AAO37688.1.
M32508 Genomic DNA. Translation: AAA63225.1.
CCDSiCCDS34379.1.
PIRiA28834.
RefSeqiNP_005507.3. NM_005516.5.
UniGeneiHs.650174.

Genome annotation databases

EnsembliENST00000383597; ENSP00000373091; ENSG00000206493.
ENST00000415289; ENSP00000409910; ENSG00000229252.
ENST00000415649; ENSP00000390707; ENSG00000233904.
ENST00000427936; ENSP00000397420; ENSG00000230254.
GeneIDi3133.
KEGGihsa:3133.

Polymorphism databases

DMDMi34395942.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M20022 mRNA. Translation: AAA52655.1 .
AJ293263 mRNA. Translation: CAC07212.1 .
AJ293264 mRNA. Translation: CAC07213.1 .
AF523274 Genomic DNA. Translation: AAM74969.1 .
AF523275 Genomic DNA. Translation: AAM74970.1 .
AF523276 Genomic DNA. Translation: AAM74971.1 .
AF523277 Genomic DNA. Translation: AAM74972.1 .
AF523278 Genomic DNA. Translation: AAM74973.1 .
AF523279 Genomic DNA. Translation: AAM74974.1 .
AF523280 Genomic DNA. Translation: AAM74975.1 .
AF523281 Genomic DNA. Translation: AAM74976.1 .
AF523282 Genomic DNA. Translation: AAM74977.1 .
AF523283 Genomic DNA. Translation: AAM74978.1 .
BA000025 Genomic DNA. Translation: BAB63328.1 .
BC002578 mRNA. Translation: AAH02578.1 .
BC004297 mRNA. Translation: AAH04297.1 .
M21533 Genomic DNA. Translation: AAA59835.1 .
AY221103 mRNA. Translation: AAO34408.1 .
AY216681 mRNA. Translation: AAO37688.1 .
M32508 Genomic DNA. Translation: AAA63225.1 .
CCDSi CCDS34379.1.
PIRi A28834.
RefSeqi NP_005507.3. NM_005516.5.
UniGenei Hs.650174.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1KPR X-ray 2.80 A/C 22-295 [» ]
1KTL X-ray 3.10 A/C 22-295 [» ]
1MHE X-ray 2.85 A/C 22-295 [» ]
2ESV X-ray 2.60 A 23-297 [» ]
3AM8 X-ray 2.80 A/B 22-297 [» ]
3BZE X-ray 2.50 A/C/E/G 23-295 [» ]
3BZF X-ray 2.50 A/C 22-297 [» ]
3CDG X-ray 3.40 A/C 23-295 [» ]
3CII X-ray 4.41 A/D 23-295 [» ]
ProteinModelPortali P13747.
SMRi P13747. Positions 22-297.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 109378. 6 interactions.
DIPi DIP-32N.
IntActi P13747. 18 interactions.
STRINGi 9606.ENSP00000373091.

PTM databases

PhosphoSitei P13747.

Polymorphism databases

DMDMi 34395942.

Proteomic databases

MaxQBi P13747.
PaxDbi P13747.
PRIDEi P13747.

Protocols and materials databases

DNASUi 3133.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000383597 ; ENSP00000373091 ; ENSG00000206493 .
ENST00000415289 ; ENSP00000409910 ; ENSG00000229252 .
ENST00000415649 ; ENSP00000390707 ; ENSG00000233904 .
ENST00000427936 ; ENSP00000397420 ; ENSG00000230254 .
GeneIDi 3133.
KEGGi hsa:3133.

Organism-specific databases

CTDi 3133.
GeneCardsi GC06P030457.
GC06Pj30447.
GC06Pk30447.
GC06Pn30446.
GC06Po30448.
HGNCi HGNC:4962. HLA-E.
HPAi CAB024589.
HPA031454.
MIMi 143010. gene.
neXtProti NX_P13747.
PharmGKBi PA35081.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG329718.
HOVERGENi HBG016709.
InParanoidi P13747.
KOi K06751.
OMAi GPRYSHA.
PhylomeDBi P13747.

Enzyme and pathway databases

Reactomei REACT_111168. Endosomal/Vacuolar pathway.
REACT_111178. ER-Phagosome pathway.
REACT_11152. Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.
REACT_147694. DAP12 interactions.
REACT_147814. DAP12 signaling.
REACT_25078. Interferon gamma signaling.
REACT_25162. Interferon alpha/beta signaling.
REACT_75795. Antigen Presentation: Folding, assembly and peptide loading of class I MHC.

Miscellaneous databases

ChiTaRSi HLA-E. human.
EvolutionaryTracei P13747.
GeneWikii HLA-E.
GenomeRNAii 3133.
NextBioi 12427.
PROi P13747.
SOURCEi Search...

Gene expression databases

CleanExi HS_HLA-E.
Genevestigatori P13747.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view ]
Pfami PF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view ]
PRINTSi PR01638. MHCCLASSI.
SMARTi SM00407. IGc1. 1 hit.
[Graphical view ]
SUPFAMi SSF54452. SSF54452. 1 hit.
PROSITEi PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Isolation and nucleotide sequence of a cDNA clone encoding a novel HLA class I gene."
    Mizuno S., Trapani J.A., Koller B.H., Dupont B., Yang S.Y.
    J. Immunol. 140:4024-4030(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE E*01:01).
  2. "Cell surface expression of HLA-E: interaction with human beta-2 microglobulin and allelic differences."
    Ulbrecht M., Courturier A., Martinozzi S., Pla M., Srivastava R., Peterson P.A., Weiss E.H.
    Eur. J. Immunol. 29:537-547(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE (ALLELES E*01:01 AND E*01:03).
  3. "HLA-E, F, and G polymorphism: genomic sequence defines new variation spanning the nonclassical class I genes."
    Ishitani A., Miki A., Williams L.M., Moore Y., Geraghty D.E.
    Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE (ALLELES E*01:01 AND E*01:03).
  4. "Homo sapiens 2,229,817bp genomic DNA of 6p21.3 HLA class I region."
    Shiina S., Tamiya G., Oka A., Inoko H.
    Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (ALLELE E*01:01).
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ALLELE E*01:01).
    Tissue: Ovarian adenocarcinoma and Pancreas.
  6. "HLA-E. A novel HLA class I gene expressed in resting T lymphocytes."
    Koller B.H., Geraghty D.E., Shimizu Y., Demars R., Orr H.T.
    J. Immunol. 141:897-904(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE E*0102).
  7. Ulbrecht M.
    Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE (ALLELE E*01:03).
  8. "A new variant of HLA-E*010303 with three synonymous mutations."
    He X., Xu L., Liu Y., Zeng Y.
    Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE E*01:03).
  9. "Cloning of HLA-E cDNA from activated peripheral leukocytes."
    He X., Xu L., Liu Y., Zeng Y.
    Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ALLELE E*01:03).
  10. "Polymorphism in the human class I MHC locus HLA-E in Japanese."
    Ohya K., Kondo K., Mizuno S.
    Immunogenetics 32:205-209(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 112-203 (ALLELE E*01:04).
    Tissue: Peripheral blood.
  11. "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
    Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.
    Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-107.
    Tissue: Leukemic T-cell.
  12. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  13. "Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E."
    O'Callaghan C.A., Tormo J., Willcox B.E., Braud V.M., Jakobsen B.K., Stuart D.I., McMichael A.J., Bell J.I., Jones E.Y.
    Mol. Cell 1:531-541(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.85 ANGSTROMS) OF 22-295.
  14. "Definitive high resolution typing of HLA-E allelic polymorphisms: identifying potential errors in existing allele data."
    Grimsley C., Kawasaki A., Gassner C., Sageshima N., Nose Y., Hatake K., Geraghty D.E., Ishitani A.
    Tissue Antigens 60:206-212(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: POLYMORPHISM, QUESTIONING ON ALLELES E*0102 AND E*01:04.

Entry informationi

Entry nameiHLAE_HUMAN
AccessioniPrimary (citable) accession number: P13747
Secondary accession number(s): Q30169
, Q9BT83, Q9GIY7, Q9GIY8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: August 29, 2003
Last modified: September 3, 2014
This is version 152 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The existence of allele E*0102 (1 Publication) and allele E*0104 (1 Publication) is uncertain. The alleles could not be confirmed in further studies (1 Publication).

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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