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Protein

Major surface antigen p30

Gene
N/A
Organism
Toxoplasma gondii
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Major surface antigen p30
OrganismiToxoplasma gondii
Taxonomic identifieri5811 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeToxoplasma

Subcellular locationi

  • Parasitophorous vacuole

  • Note: Surface of extra- and intracellular tachyzoites and also component of the vesicular network within the parasitophorous vacuole.

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 4747Sequence analysisAdd
BLAST
Chaini48 – 336289Major surface antigen p30PRO_0000021982Add
BLAST

Expressioni

Developmental stagei

Detected only in rapidly dividing and invasive tachyzoites.

Interactioni

Protein-protein interaction databases

STRINGi5811.TGME49_033460.

Structurei

Secondary structure

1
336
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi55 – 595Combined sources
Beta strandi62 – 7211Combined sources
Beta strandi77 – 815Combined sources
Beta strandi87 – 904Combined sources
Helixi91 – 944Combined sources
Beta strandi95 – 984Combined sources
Beta strandi101 – 1033Combined sources
Turni111 – 1133Combined sources
Helixi117 – 1193Combined sources
Helixi126 – 1283Combined sources
Beta strandi129 – 1313Combined sources
Turni136 – 1394Combined sources
Beta strandi141 – 1444Combined sources
Helixi147 – 1493Combined sources
Beta strandi155 – 16410Combined sources
Helixi166 – 1683Combined sources
Beta strandi170 – 1767Combined sources
Beta strandi182 – 1843Combined sources
Beta strandi187 – 1893Combined sources
Beta strandi196 – 2038Combined sources
Beta strandi210 – 2145Combined sources
Beta strandi219 – 2257Combined sources
Beta strandi228 – 2303Combined sources
Beta strandi232 – 2354Combined sources
Beta strandi240 – 2423Combined sources
Helixi243 – 2453Combined sources
Beta strandi255 – 26814Combined sources
Turni271 – 2733Combined sources
Beta strandi279 – 2879Combined sources
Beta strandi289 – 30113Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1KZQX-ray1.70A/B48-336[»]
1YNTX-ray3.10F/G50-303[»]
ProteinModelPortaliP13664.
SMRiP13664. Positions 51-303.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP13664.

Family & Domainsi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.60.40.1320. 2 hits.
InterProiIPR007226. SRS_dom.
IPR028352. Surface_antig_SAG1.
[Graphical view]
PfamiPF04092. SAG. 2 hits.
[Graphical view]
PRINTSiPR01801. SURFCEANTIGN.
SUPFAMiSSF74877. SSF74877. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P13664-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVSLHHFII SSGFLTSMFP KAVRRAVTAG VFAAPTLMSF LRCGVMASDP
60 70 80 90 100
PLVANQVVTC PDKKSTAAVI LTPTENHFTL KCPKTALTEP PTLAYSPNRQ
110 120 130 140 150
ICPAGTTSSC TSKAVTLSSL IPEAEDSWWT GDSASLDTAG IKLTVPIEKF
160 170 180 190 200
PVTTQTFVVG CIKGDDAQSC MVTVTVQARA SSVVNNVARC SYGADSTLGP
210 220 230 240 250
VKLSAEGPTT MTLVCGKDGV KVPQDNNQYC SGTTLTGCNE KSFKDILPKL
260 270 280 290 300
TENPWQGNAS SDKGATLTIK KEAFPAESKS VIIGCTGGSP EKHHCTVKLE
310 320 330
FAGAAGSAKS AAGTASHVSI FAMVIGLIGS IAACVA
Length:336
Mass (Da):34,829
Last modified:January 1, 1990 - v1
Checksum:i96C7BCEB2EB97FFE
GO

Sequence cautioni

The sequence CAA32245 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14080 Genomic DNA. Translation: CAA32244.1.
X14080 Genomic DNA. Translation: CAA32245.1. Different initiation.
S76248 Genomic DNA. Translation: AAB33440.1.
PIRiA30527.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14080 Genomic DNA. Translation: CAA32244.1.
X14080 Genomic DNA. Translation: CAA32245.1. Different initiation.
S76248 Genomic DNA. Translation: AAB33440.1.
PIRiA30527.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1KZQX-ray1.70A/B48-336[»]
1YNTX-ray3.10F/G50-303[»]
ProteinModelPortaliP13664.
SMRiP13664. Positions 51-303.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5811.TGME49_033460.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP13664.

Family and domain databases

Gene3Di2.60.40.1320. 2 hits.
InterProiIPR007226. SRS_dom.
IPR028352. Surface_antig_SAG1.
[Graphical view]
PfamiPF04092. SAG. 2 hits.
[Graphical view]
PRINTSiPR01801. SURFCEANTIGN.
SUPFAMiSSF74877. SSF74877. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiP30_TOXGO
AccessioniPrimary (citable) accession number: P13664
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: December 9, 2015
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Caution

It is uncertain whether Met-1 or Met-18 is the initiator.Curated

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.