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Protein

Major surface antigen p30

Gene
N/A
Organism
Toxoplasma gondii
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Major surface antigen p30
OrganismiToxoplasma gondii
Taxonomic identifieri5811 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeToxoplasma

Subcellular locationi

  • Parasitophorous vacuole

  • Note: Surface of extra- and intracellular tachyzoites and also component of the vesicular network within the parasitophorous vacuole.

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 47Sequence analysisAdd BLAST47
ChainiPRO_000002198248 – 336Major surface antigen p30Add BLAST289

Expressioni

Developmental stagei

Detected only in rapidly dividing and invasive tachyzoites.

Interactioni

Protein-protein interaction databases

STRINGi5811.TGME49_033460.

Structurei

Secondary structure

1336
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi55 – 59Combined sources5
Beta strandi62 – 72Combined sources11
Beta strandi77 – 81Combined sources5
Beta strandi87 – 90Combined sources4
Helixi91 – 94Combined sources4
Beta strandi95 – 98Combined sources4
Beta strandi101 – 103Combined sources3
Turni111 – 113Combined sources3
Helixi117 – 119Combined sources3
Helixi126 – 128Combined sources3
Beta strandi129 – 131Combined sources3
Turni136 – 139Combined sources4
Beta strandi141 – 144Combined sources4
Helixi147 – 149Combined sources3
Beta strandi155 – 164Combined sources10
Helixi166 – 168Combined sources3
Beta strandi170 – 176Combined sources7
Beta strandi182 – 184Combined sources3
Beta strandi187 – 189Combined sources3
Beta strandi196 – 203Combined sources8
Beta strandi210 – 214Combined sources5
Beta strandi219 – 225Combined sources7
Beta strandi228 – 230Combined sources3
Beta strandi232 – 235Combined sources4
Beta strandi240 – 242Combined sources3
Helixi243 – 245Combined sources3
Beta strandi255 – 268Combined sources14
Turni271 – 273Combined sources3
Beta strandi279 – 287Combined sources9
Beta strandi289 – 301Combined sources13

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1KZQX-ray1.70A/B48-336[»]
1YNTX-ray3.10F/G50-303[»]
ProteinModelPortaliP13664.
SMRiP13664.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP13664.

Family & Domainsi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.60.40.1320. 2 hits.
InterProiIPR007226. SRS_dom.
IPR028352. Surface_antig_SAG1.
[Graphical view]
PfamiPF04092. SAG. 2 hits.
[Graphical view]
PRINTSiPR01801. SURFCEANTIGN.
SUPFAMiSSF74877. SSF74877. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P13664-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVSLHHFII SSGFLTSMFP KAVRRAVTAG VFAAPTLMSF LRCGVMASDP
60 70 80 90 100
PLVANQVVTC PDKKSTAAVI LTPTENHFTL KCPKTALTEP PTLAYSPNRQ
110 120 130 140 150
ICPAGTTSSC TSKAVTLSSL IPEAEDSWWT GDSASLDTAG IKLTVPIEKF
160 170 180 190 200
PVTTQTFVVG CIKGDDAQSC MVTVTVQARA SSVVNNVARC SYGADSTLGP
210 220 230 240 250
VKLSAEGPTT MTLVCGKDGV KVPQDNNQYC SGTTLTGCNE KSFKDILPKL
260 270 280 290 300
TENPWQGNAS SDKGATLTIK KEAFPAESKS VIIGCTGGSP EKHHCTVKLE
310 320 330
FAGAAGSAKS AAGTASHVSI FAMVIGLIGS IAACVA
Length:336
Mass (Da):34,829
Last modified:January 1, 1990 - v1
Checksum:i96C7BCEB2EB97FFE
GO

Sequence cautioni

The sequence CAA32245 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14080 Genomic DNA. Translation: CAA32244.1.
X14080 Genomic DNA. Translation: CAA32245.1. Different initiation.
S76248 Genomic DNA. Translation: AAB33440.1.
PIRiA30527.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14080 Genomic DNA. Translation: CAA32244.1.
X14080 Genomic DNA. Translation: CAA32245.1. Different initiation.
S76248 Genomic DNA. Translation: AAB33440.1.
PIRiA30527.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1KZQX-ray1.70A/B48-336[»]
1YNTX-ray3.10F/G50-303[»]
ProteinModelPortaliP13664.
SMRiP13664.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5811.TGME49_033460.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP13664.

Family and domain databases

Gene3Di2.60.40.1320. 2 hits.
InterProiIPR007226. SRS_dom.
IPR028352. Surface_antig_SAG1.
[Graphical view]
PfamiPF04092. SAG. 2 hits.
[Graphical view]
PRINTSiPR01801. SURFCEANTIGN.
SUPFAMiSSF74877. SSF74877. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiP30_TOXGO
AccessioniPrimary (citable) accession number: P13664
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: November 2, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Caution

It is uncertain whether Met-1 or Met-18 is the initiator.Curated

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.