SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P13595

- NCAM1_MOUSE

UniProt

P13595 - NCAM1_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Neural cell adhesion molecule 1
Gene
Ncam1, Ncam
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

GO - Molecular functioni

  1. heparin binding Source: UniProtKB-KW
  2. protein binding Source: IntAct

GO - Biological processi

  1. cell surface receptor signaling pathway Source: MGI
  2. homotypic cell-cell adhesion Source: MGI
  3. neuron projection development Source: MGI
  4. positive regulation of calcium-mediated signaling Source: MGI
  5. regulation of exocyst assembly Source: MGI
Complete GO annotation...

Keywords - Biological processi

Cell adhesion

Keywords - Ligandi

Heparin-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Neural cell adhesion molecule 1
Short name:
N-CAM-1
Short name:
NCAM-1
Alternative name(s):
CD_antigen: CD56
Gene namesi
Name:Ncam1
Synonyms:Ncam
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:97281. Ncam1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini20 – 711692Extracellular Reviewed prediction
Add
BLAST
Transmembranei712 – 72918Helical; Reviewed prediction
Add
BLAST
Topological domaini730 – 1115386Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. anchored component of membrane Source: UniProtKB-KW
  2. axon Source: MGI
  3. cell-cell junction Source: MGI
  4. external side of plasma membrane Source: MGI
  5. growth cone Source: MGI
  6. integral component of membrane Source: UniProtKB-KW
  7. neuronal cell body Source: MGI
  8. plasma membrane Source: Reactome
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 19191 Publication
Add
BLAST
Chaini20 – 11151096Neural cell adhesion molecule 1
PRO_0000015012Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi41 ↔ 962 Publications
Disulfide bondi139 ↔ 1892 Publications
Glycosylationi222 – 2221N-linked (GlcNAc...); partial1 Publication
Disulfide bondi235 ↔ 288 Inferred
Glycosylationi316 – 3161N-linked (GlcNAc...)1 Publication
Disulfide bondi330 ↔ 386 Inferred
Glycosylationi348 – 3481N-linked (GlcNAc...)1 Publication
Glycosylationi424 – 4241N-linked (GlcNAc...)1 Publication
Disulfide bondi427 ↔ 480 Inferred
Glycosylationi450 – 4501N-linked (GlcNAc...)3 Publications
Glycosylationi453 – 4531N-linked (GlcNAc...); atypical1 Publication
Glycosylationi479 – 4791N-linked (GlcNAc...)1 Publication
Modified residuei774 – 7741Phosphoserine1 Publication
Modified residuei946 – 9461Phosphoserine1 Publication
Modified residuei958 – 9581Phosphoserine1 Publication
Modified residuei1005 – 10051Phosphoserine1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein, Phosphoprotein

Proteomic databases

MaxQBiP13595.
PaxDbiP13595.
PRIDEiP13595.

PTM databases

PhosphoSiteiP13595.

Expressioni

Gene expression databases

GenevestigatoriP13595.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
Fgfr2P218032EBI-774943,EBI-6286942

Protein-protein interaction databases

BioGridi201699. 3 interactions.
IntActiP13595. 6 interactions.
MINTiMINT-1176881.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi21 – 3212
Beta strandi37 – 448
Beta strandi47 – 493
Beta strandi51 – 566
Turni57 – 593
Beta strandi64 – 7310
Beta strandi75 – 773
Beta strandi79 – 857
Turni88 – 903
Beta strandi92 – 998
Beta strandi101 – 1033
Beta strandi105 – 11511
Beta strandi119 – 1224
Beta strandi125 – 1284
Beta strandi133 – 1375
Beta strandi140 – 1434
Beta strandi145 – 15713
Helixi158 – 1614
Beta strandi166 – 1683
Beta strandi174 – 1785
Beta strandi185 – 1939
Turni194 – 1974
Beta strandi198 – 20710

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2NCMNMR-A20-116[»]
3NCMNMR-A119-208[»]
ProteinModelPortaliP13595.
SMRiP13595. Positions 20-696.

Miscellaneous databases

EvolutionaryTraceiP13595.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 11192Ig-like C2-type 1
Add
BLAST
Domaini116 – 20590Ig-like C2-type 2
Add
BLAST
Domaini212 – 30291Ig-like C2-type 3
Add
BLAST
Domaini309 – 40294Ig-like C2-type 4
Add
BLAST
Domaini407 – 49286Ig-like C2-type 5
Add
BLAST
Domaini500 – 599100Fibronectin type-III 1
Add
BLAST
Domaini601 – 69696Fibronectin type-III 2
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni152 – 1565Heparin-binding Reviewed prediction
Regioni161 – 1655Heparin-binding Reviewed prediction

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG308439.
HOVERGENiHBG052579.
InParanoidiP13595.
KOiK06491.
PhylomeDBiP13595.

Family and domain databases

Gene3Di2.60.40.10. 7 hits.
InterProiIPR003961. Fibronectin_type3.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003598. Ig_sub2.
IPR009138. Neural_cell_adh.
[Graphical view]
PfamiPF00041. fn3. 2 hits.
PF07679. I-set. 5 hits.
[Graphical view]
PRINTSiPR01838. NCAMFAMILY.
SMARTiSM00060. FN3. 2 hits.
SM00408. IGc2. 5 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 1 hit.
PROSITEiPS50853. FN3. 2 hits.
PS50835. IG_LIKE. 5 hits.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: P13595-1) [UniParc]FASTAAdd to Basket

Also known as: N-CAM 180

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MLRTKDLIWT LFFLGTAVSL QVDIVPSQGE ISVGESKFFL CQVAGDAKDK     50
DISWFSPNGE KLSPNQQRIS VVWNDDDSST LTIYNANIDD AGIYKCVVTA 100
EDGTQSEATV NVKIFQKLMF KNAPTPQEFK EGEDAVIVCD VVSSLPPTII 150
WKHKGRDVIL KKDVRFIVLS NNYLQIRGIK KTDEGTYRCE GRILARGEIN 200
FKDIQVIVNV PPTVQARQSI VNATANLGQS VTLVCDADGF PEPTMSWTKD 250
GEPIENEEED DEKHIFSDDS SELTIRNVDK NDEAEYVCIA ENKAGEQDAS 300
IHLKVFAKPK ITYVENQTAM ELEEQVTLTC EASGDPIPSI TWRTSTRNIS 350
SEEKTLDGHM VVRSHARVSS LTLKSIQYTD AGEYICTASN TIGQDSQSMY 400
LEFQYAPKLQ GPVAVYTWEG NQVNITCEVF AYPSATISWF RDGQLLPSSN 450
YSNIKIYNTP SASYLEVTPD SENDFGNYNC TAVNRIGQES LEFILVQADT 500
PSSPSIDRVE PYSSTAQVQF DEPEATGGVP ILKYKAEWKS LGEESWHFKW 550
YDAKEANMEG IVTIMGLKPE TRYSVRLAAL NGKGLGEISA ATEFKTQPVR 600
EPSAPKLEGQ MGEDGNSIKV NLIKQDDGGS PIRHYLVKYR ALASEWKPEI 650
RLPSGSDHVM LKSLDWNAEY EVYVVAENQQ GKSKAAHFVF RTSAQPTAIP 700
ANGSPTAGLS TGAIVGILIV IFVLLLVVMD ITCYFLNKCG LLMCIAVNLC 750
GKAGPGAKGK DMEEGKAAFS KDESKEPIVE VRTEEERTPN HDGGKHTEPN 800
ETTPLTEPEL PADTTATVED MLPSVTTVTT NSDTITETFA TAQNSPTSET 850
TTLTSSIAPP ATTVPDSNSV PAGQATPSKG VTASSSSPAS APKVAPLVDL 900
SDTPTSAPSA SNLSSTVLAN QGAVLSPSTP ASAGETSKAP PASKASPAPT 950
PTPAGAASPL AAVAAPATDA PQAKQEAPST KGPDPEPTQP GTVKNPPEAA 1000
TAPASPKSKA ATTNPSQGED LKMDEGNFKT PDIDLAKDVF AALGSPRPAT 1050
GASGQASELA PSPADSAVPP APAKTEKGPV ETKSEPPESE AKPAPTEVKT 1100
VPNDATQTKE NESKA 1115
Length:1,115
Mass (Da):119,427
Last modified:July 22, 2008 - v3
Checksum:i78AF831BABD23918
GO
Isoform 2 (identifier: P13595-2) [UniParc]FASTAAdd to Basket

Also known as: N-CAM 140

The sequence of this isoform differs from the canonical sequence as follows:
     810-1076: Missing.

Show »
Length:848
Mass (Da):93,540
Checksum:i4D77D553F474AD8E
GO
Isoform 3 (identifier: P13595-3) [UniParc] [UniParc]FASTAAdd to Basket

Also known as: N-CAM 120

The sequence of this isoform differs from the canonical sequence as follows:
     702-725: NGSPTAGLSTGAIVGILIVIFVLL → TLGGSSTSYTLVSLLFSAVTLLLL
     726-1115: Missing.

Note: GPI-anchor amidated serine at position Ser-706.

Show »
Length:725
Mass (Da):80,406
Checksum:i97867C2A61594CC4
GO
Isoform 4 (identifier: P13595-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     601-605: EPSAP → KSSLF
     606-1115: Missing.

Show »
Length:605
Mass (Da):67,353
Checksum:iD497D834C34EAEC0
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei601 – 6055EPSAP → KSSLF in isoform 4.
VSP_034826
Alternative sequencei606 – 1115510Missing in isoform 4.
VSP_034827Add
BLAST
Alternative sequencei702 – 72524NGSPT…IFVLL → TLGGSSTSYTLVSLLFSAVT LLLL in isoform 3.
VSP_034828Add
BLAST
Alternative sequencei726 – 1115390Missing in isoform 3.
VSP_034829Add
BLAST
Alternative sequencei810 – 1076267Missing in isoform 2.
VSP_002588Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti20 – 201L → M in CAA33148. 1 Publication
Sequence conflicti158 – 1581V → F in AAH11310. 1 Publication
Sequence conflicti261 – 2688DEKHIFSD → ERSRSSVS in CAA68263. 1 Publication
Sequence conflicti273 – 2731L → V in CAA68263. 1 Publication
Sequence conflicti354 – 3552KT → QD in CAA68263. 1 Publication
Sequence conflicti379 – 3791T → R in CAA68263. 1 Publication
Sequence conflicti379 – 3791T → R in CAA33148. 1 Publication
Sequence conflicti385 – 3851I → M in CAA68263. 1 Publication
Sequence conflicti385 – 3851I → M in CAA33148. 1 Publication
Sequence conflicti399 – 4002MY → ID in CAA68263. 1 Publication
Sequence conflicti399 – 4002MY → ID in CAA33148. 1 Publication
Sequence conflicti403 – 4031F → V in AAH11310. 1 Publication
Sequence conflicti403 – 4031F → V in BAC34554. 1 Publication
Sequence conflicti403 – 4031F → V in BAC38551. 1 Publication
Sequence conflicti549 – 5491K → T in CAA68263. 1 Publication
Sequence conflicti572 – 5721R → T in CAA68263. 1 Publication
Sequence conflicti575 – 5751V → D in CAA68263. 1 Publication
Sequence conflicti589 – 5946SAATEF → MQPSES in CAA68263. 1 Publication
Sequence conflicti600 – 6023REP → PEL in CAA68263. 1 Publication
Sequence conflicti657 – 6571D → H in CAA68263. 1 Publication
Sequence conflicti733 – 7331C → W in BAC34554. 1 Publication
Sequence conflicti1082 – 10821T → A in BAC34554. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y00051 mRNA. Translation: CAA68263.1.
BC011310 mRNA. Translation: AAH11310.1.
AK051197 mRNA. Translation: BAC34554.2.
AK082621 mRNA. Translation: BAC38551.2.
X15049 mRNA. Translation: CAA33148.1.
X15051 mRNA. Translation: CAA33150.1.
X15052 mRNA. Translation: CAA33151.1.
X06328 mRNA. Translation: CAA29641.1.
X07195 Genomic DNA. Translation: CAA30173.1.
X07197 Genomic DNA. Translation: CAA30175.1.
X07198 Genomic DNA. Translation: CAB40820.1.
X07200 Genomic DNA. Translation: CAA30177.1.
X07244 mRNA. Translation: CAA30230.1.
CCDSiCCDS40617.1. [P13595-2]
CCDS40618.1. [P13595-3]
PIRiA29673. IJMSNL.
RefSeqiNP_001074914.1. NM_001081445.1.
NP_001106675.1. NM_001113204.1.
NP_035005.2. NM_010875.3.
UniGeneiMm.439182.
Mm.4974.

Genome annotation databases

GeneIDi17967.
KEGGimmu:17967.
UCSCiuc009pje.2. mouse. [P13595-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y00051 mRNA. Translation: CAA68263.1 .
BC011310 mRNA. Translation: AAH11310.1 .
AK051197 mRNA. Translation: BAC34554.2 .
AK082621 mRNA. Translation: BAC38551.2 .
X15049 mRNA. Translation: CAA33148.1 .
X15051 mRNA. Translation: CAA33150.1 .
X15052 mRNA. Translation: CAA33151.1 .
X06328 mRNA. Translation: CAA29641.1 .
X07195 Genomic DNA. Translation: CAA30173.1 .
X07197 Genomic DNA. Translation: CAA30175.1 .
X07198 Genomic DNA. Translation: CAB40820.1 .
X07200 Genomic DNA. Translation: CAA30177.1 .
X07244 mRNA. Translation: CAA30230.1 .
CCDSi CCDS40617.1. [P13595-2 ]
CCDS40618.1. [P13595-3 ]
PIRi A29673. IJMSNL.
RefSeqi NP_001074914.1. NM_001081445.1.
NP_001106675.1. NM_001113204.1.
NP_035005.2. NM_010875.3.
UniGenei Mm.439182.
Mm.4974.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2NCM NMR - A 20-116 [» ]
3NCM NMR - A 119-208 [» ]
ProteinModelPortali P13595.
SMRi P13595. Positions 20-696.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 201699. 3 interactions.
IntActi P13595. 6 interactions.
MINTi MINT-1176881.

PTM databases

PhosphoSitei P13595.

Proteomic databases

MaxQBi P13595.
PaxDbi P13595.
PRIDEi P13595.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 17967.
KEGGi mmu:17967.
UCSCi uc009pje.2. mouse. [P13595-1 ]

Organism-specific databases

CTDi 4684.
MGIi MGI:97281. Ncam1.

Phylogenomic databases

eggNOGi NOG308439.
HOVERGENi HBG052579.
InParanoidi P13595.
KOi K06491.
PhylomeDBi P13595.

Miscellaneous databases

ChiTaRSi NCAM1. mouse.
EvolutionaryTracei P13595.
NextBioi 292903.
PROi P13595.
SOURCEi Search...

Gene expression databases

Genevestigatori P13595.

Family and domain databases

Gene3Di 2.60.40.10. 7 hits.
InterProi IPR003961. Fibronectin_type3.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003598. Ig_sub2.
IPR009138. Neural_cell_adh.
[Graphical view ]
Pfami PF00041. fn3. 2 hits.
PF07679. I-set. 5 hits.
[Graphical view ]
PRINTSi PR01838. NCAMFAMILY.
SMARTi SM00060. FN3. 2 hits.
SM00408. IGc2. 5 hits.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 1 hit.
PROSITEi PS50853. FN3. 2 hits.
PS50835. IG_LIKE. 5 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Isolation and nucleotide sequence of mouse NCAM cDNA that codes for a Mr 79,000 polypeptide without a membrane-spanning region."
    Barthels D., Santoni M.-J., Wille W., Ruppert C., Chaix J.-C., Hirsch M.-R., Fontecilla-Camps J.-C., Goridis C.
    EMBO J. 6:907-914(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3).
    Strain: C57BL/6.
    Tissue: Brain.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
    Strain: FVB/N.
    Tissue: Mammary tumor.
  3. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1106 (ISOFORM 2).
    Strain: C57BL/6J.
    Tissue: Cerebellum and Spinal ganglion.
  4. "Differential exon usage involving an unusual splicing mechanism generates at least eight types of NCAM cDNA in mouse brain."
    Santoni M.J., Barthels D., Vopper G., Boned A., Goridis C., Wille W.
    EMBO J. 8:385-392(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 20-700 AND 702-1115 (ISOFORMS 1 AND 2).
    Strain: C57BL/6.
    Tissue: Brain.
  5. "Structural and immunological characterization of the amino-terminal domain of mammalian neural cell adhesion molecules."
    Rougon G., Marshak D.R.
    J. Biol. Chem. 261:3396-3401(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 20-36.
  6. Lubec G., Kang S.U.
    Submitted (APR-2007) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 38-48; 122-152; 166-177; 555-572; 584-595; 607-619; 652-662 AND 685-691, IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: C57BL/6.
    Tissue: Brain.
  7. "Analysis of cDNA clones that code for the transmembrane forms of the mouse neural cell adhesion molecule (NCAM) and are generated by alternative RNA splicing."
    Santoni M.-J., Barthels D., Barbas J.A., Hirsch M.-R., Steinmetz M., Goridis C., Wille W.
    Nucleic Acids Res. 15:8621-8641(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 529-1115 (ISOFORM 2).
    Strain: C57BL/6.
  8. "Differential splicing and alternative polyadenylation generates distinct NCAM transcripts and proteins in the mouse."
    Barbas J.A., Chaix J.-C., Steinmetz M., Goridis C.
    EMBO J. 7:625-632(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 642-1115.
  9. "NCAM-180, the large isoform of the neural cell adhesion molecule of the mouse, is encoded by an alternatively spliced transcript."
    Barthels D., Vopper G., Wille W.
    Nucleic Acids Res. 16:4217-4225(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 804-1081 (ISOFORM 1).
    Strain: C57BL/6J.
    Tissue: Brain.
  10. "Identification of N-glycosylation sites of the murine neural cell adhesion molecule NCAM by MALDI-TOF and MALDI-FTICR mass spectrometry."
    Albach C., Damoc E., Denzinger T., Schachner M., Przybylski M., Schmitz B.
    Anal. Bioanal. Chem. 378:1129-1135(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION AT ASN-222; ASN-316; ASN-348; ASN-424; ASN-450 AND ASN-479, IDENTIFICATION BY MASS SPECTROMETRY.
    Tissue: Brain.
  11. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-946; SER-958 AND SER-1005, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic brain.
  12. "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
    Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.
    Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-774, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brain.
  13. "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation."
    Gundry R.L., Raginski K., Tarasova Y., Tchernyshyov I., Bausch-Fluck D., Elliott S.T., Boheler K.R., Van Eyk J.E., Wollscheid B.
    Mol. Cell. Proteomics 8:2555-2569(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-450 AND ASN-453.
    Tissue: Myoblast.
  14. "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
    Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.
    Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-450.
  15. "The three-dimensional structure of the first domain of neural cell adhesion molecule."
    Thomsen N.K., Soroka V., Jensen P.H., Berezin V., Kiselyov V.V., Bock E., Poulsen F.M.
    Nat. Struct. Biol. 3:581-585(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR OF 20-116, DISULFIDE BONDS.
  16. "Structure and interactions of NCAM modules 1 and 2, basic elements in neural cell adhesion."
    Jensen P.H., Soroka V., Thomsen N.K., Ralets I., Berezin V., Bock E., Poulsen F.M.
    Nat. Struct. Biol. 6:486-493(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR OF 119-208, DISULFIDE BONDS.

Entry informationi

Entry nameiNCAM1_MOUSE
AccessioniPrimary (citable) accession number: P13595
Secondary accession number(s): P13594
, Q61949, Q61950, Q6LBU8, Q8BQ96, Q8C4B2, Q921P2, Q9R2A7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: July 22, 2008
Last modified: September 3, 2014
This is version 149 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi