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Protein

Colicin-E9 immunity protein

Gene

imm

Organism
Escherichia coli
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This protein is able to protect a cell, which harbors the plasmid ColE9 encoding colicin E9, against colicin E9, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity.

GO - Molecular functioni

  • protein domain specific binding Source: CAFA
  • toxic substance binding Source: InterPro

GO - Biological processi

Keywordsi

Biological processBacteriocin immunity

Names & Taxonomyi

Protein namesi
Recommended name:
Colicin-E9 immunity protein
Alternative name(s):
ImmE9
Microcin-E9 immunity protein
Gene namesi
Name:imm
Synonyms:ceiE9
Encoded oniPlasmid ColE9-J0 Publication
OrganismiEscherichia coli
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

Subcellular locationi

GO - Cellular componenti

  • protein-containing complex Source: CAFA

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002187111 – 86Colicin-E9 immunity proteinAdd BLAST86

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

  • protein domain specific binding Source: CAFA

Protein-protein interaction databases

DIPiDIP-16991N
IntActiP13479, 2 interactors

Structurei

Secondary structure

186
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi7 – 9Combined sources3
Helixi12 – 23Combined sources12
Beta strandi27 – 29Combined sources3
Helixi30 – 44Combined sources15
Turni47 – 50Combined sources4
Helixi51 – 54Combined sources4
Helixi64 – 77Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1BXIX-ray2.05A1-86[»]
1E0HNMR-A1-86[»]
1EMVX-ray1.70A1-86[»]
1FR2X-ray1.60A1-86[»]
1IMPNMR-A1-86[»]
1IMQNMR-A1-86[»]
2GYKX-ray1.60A/E1-86[»]
2GZEX-ray1.80A1-86[»]
2GZFX-ray1.75A1-86[»]
2GZGX-ray1.70A1-86[»]
2GZIX-ray1.70A1-86[»]
2GZJX-ray1.60A/E1-86[»]
2K5XNMR-A1-86[»]
2VLNX-ray1.60A1-86[»]
2VLOX-ray1.80A1-86[»]
2VLPX-ray2.00A1-86[»]
2VLQX-ray1.60A1-86[»]
3GJNX-ray2.48A/D1-86[»]
3GKLX-ray2.20C/D1-86[»]
5EW5X-ray3.20E/F/G/H1-86[»]
ProteinModelPortaliP13479
SMRiP13479
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP13479

Family & Domainsi

Sequence similaritiesi

Family and domain databases

CDDicd16363 Col_Im_like, 1 hit
Gene3Di1.10.1200.20, 1 hit
InterProiView protein in InterPro
IPR035900 Colicin_E_sf
IPR000290 Colicin_pyocin
PfamiView protein in Pfam
PF01320 Colicin_Pyocin, 1 hit
PRINTSiPR01299 PYOCIN
ProDomiView protein in ProDom or Entries sharing at least one domain
PD007225 Colicin_pyocin, 1 hit
SUPFAMiSSF47345 SSF47345, 1 hit

Sequencei

Sequence statusi: Complete.

P13479-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELKHSISDY TEAEFLQLVT TICNADTSSE EELVKLVTHF EEMTEHPSGS
60 70 80
DLIYYPKEGD DDSPSGIVNT VKQWRAANGK SGFKQG
Length:86
Mass (Da):9,583
Last modified:April 1, 1990 - v2
Checksum:i136CBD25D071FDB4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti26D → N in AAA23076 (PubMed:3312476).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15858 Genomic DNA Translation: CAA33863.1
M16803 Genomic DNA Translation: AAA23076.1
PIRiA32535
RefSeqiWP_012644887.1, NZ_NOAY01000099.1
YP_002533538.1, NC_011977.1

Genome annotation databases

GeneIDi7377405

Similar proteinsi

Entry informationi

Entry nameiIMM9_ECOLX
AccessioniPrimary (citable) accession number: P13479
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: April 1, 1990
Last modified: May 23, 2018
This is version 96 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Plasmid

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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