P13440 (ARGE_LEPBI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative acetylornithine deacetylase
Short name=Acetylornithinase
EC=3.5.1.16

Gene names

Name:

argE

Organism

Leptospira biflexa

Taxonomic identifier

172 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Leptospiraceae › Leptospira

Protein attributes

Sequence length	277 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	N(2)-acetyl-L-ornithine + H2O = acetate + L-ornithine.
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine from N(2)-acetyl-L-ornithine (linear): step 1/1.
Caution	Resembles portions of the beta' subunits of RNA polymerases from bacteria and chloroplasts. It was suggested that both the beta' subunit of RNA polymerases and L.biflexa ArgE-complementing activity possess N-acetylase or N-acetylornithinase activity. No homology with E.coli ArgE.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis
Molecular function	Hydrolase
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: InterPro acetylornithine deacetylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 277	277	Putative acetylornithine deacetylase		PRO_0000064672

Sequences

	Sequence		Length	Mass (Da)
	P13440 [UniParc]. Last modified January 1, 1990. Version 1. Checksum: 40434BCFA4D7ED63	FASTA	277	31,107
	10 20 30 40 50 60 MNFSKLVVRK MPAHLQKLTV KSKTKVKSLK KNEYYTIIPE TAEQEKVKVA IPIGKQIRVR 70 80 90 100 110 120 QGDFVKRGDQ LDEGNFDPHD ILAIKGPNAL HEYLVSEVQE VYRLQGVHIN DKHIEVVVRS 130 140 150 160 170 180 MLRKVIITDS GDTSFVNQQQ VDKFLFDEEN DRVEKEGGSP AQGTPVLLGL TKASLNTESY 190 200 210 220 230 240 FSAASFQETT KVLTDAAIKG KTDNLMGLKE NVIIGHMIPA GTGMKKYRDI EVFKDLPGDL 250 260 270 DWDLAIGGRG RRSFRTFRVG SCFHCHTLST CCRRGRG

References

[1]	"Nucleotide sequence analysis of a gene cloned from Leptospira biflexa serovar patoc which complements an argE defect in Escherichia coli." Zuerner R.L., Charon N.W. J. Bacteriol. 170:4548-4554(1988) [PubMed: 2844724] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Patoc I / Serovar Patoc.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M22622 Genomic DNA. Translation: AAA25260.1.
PIR	A31840.
3D structure databases
ProteinModelPortal	P13440.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR007081. RNA_pol_Rpb1_5. [Graphical view]
Pfam	PF04998. RNA_pol_Rpb1_5. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ARGE_LEPBI

Accession

Primary (citable) accession number: P13440

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 1, 1990
Last sequence update:	January 1, 1990
Last modified:	September 21, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program