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Protein

Protein Gp59

Gene

59

Organism
Enterobacteria phage T4 (Bacteriophage T4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

DNA-binding protein involved in genetic recombination and recombination-dependent DNA replication. It forms a protein complex with the gene 41 protein that partly replaces the dDA protein helicase function. It has higher affinity for single- than for double-stranded DNA. It can bind directly protein 32.

GO - Molecular functioni

GO - Biological processi

  • bidirectional double-stranded viral DNA replication Source: UniProtKB
  • DNA replication Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding
Biological processDNA replication

Names & Taxonomyi

Protein namesi
Recommended name:
Protein Gp59
Gene namesi
Name:59
OrganismiEnterobacteria phage T4 (Bacteriophage T4)
Taxonomic identifieri10665 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesMyoviridaeTevenvirinaeT4virus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000009087 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001650461 – 217Protein Gp59Add BLAST217

Interactioni

Subunit structurei

Monomer.

Structurei

Secondary structure

1217
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 4Combined sources3
Helixi16 – 30Combined sources15
Turni36 – 41Combined sources6
Helixi47 – 52Combined sources6
Helixi56 – 65Combined sources10
Helixi68 – 81Combined sources14
Helixi83 – 86Combined sources4
Helixi90 – 92Combined sources3
Helixi95 – 107Combined sources13
Helixi109 – 126Combined sources18
Helixi132 – 135Combined sources4
Turni140 – 143Combined sources4
Helixi146 – 152Combined sources7
Helixi158 – 168Combined sources11
Helixi170 – 177Combined sources8
Helixi181 – 196Combined sources16
Beta strandi197 – 199Combined sources3
Helixi201 – 216Combined sources16

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1C1KX-ray1.45A1-217[»]
ProteinModelPortaliP13342.
SMRiP13342.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP13342.

Family & Domainsi

Phylogenomic databases

KOiK18949.
OrthoDBiVOG090000O5.

Family and domain databases

Gene3Di1.10.220.50. 1 hit.
InterProiView protein in InterPro
IPR008944. Phage_T4_Gp59.
IPR015086. Phage_T4_Gp59_C.
IPR023197. Phage_T4_Gp59_domain.
IPR015085. Phage_T4_Gp59_N.
PfamiView protein in Pfam
PF08994. T4_Gp59_C. 1 hit.
PF08993. T4_Gp59_N. 1 hit.
PIRSFiPIRSF004374. Phage-associated_Gp59. 1 hit.
SUPFAMiSSF48493. SSF48493. 1 hit.

Sequencei

Sequence statusi: Complete.

P13342-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKLRMPAGG ERYIDGKSVY KLYLMIKQHM NGKYDVIKYN WCMRVSDAAY
60 70 80 90 100
QKRRDKYFFQ KLSEKYKLKE LALIFISNLV ANQDAWIGDI SDADALVFYR
110 120 130 140 150
EYIGRLKQIK FKFEEDIRNI YYFSKKVEVS AFKEIFEYNP KVQSSYIFKL
160 170 180 190 200
LQSNIISFET FILLDSFLNI IDKHDEQTDN LVWNNYSIKL KAYRKILNID
210
SQKAKNVFIE TVKSCKY
Length:217
Mass (Da):25,997
Last modified:January 1, 1990 - v1
Checksum:iB9E7DDE80DCF978C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15818 Genomic DNA. Translation: CAA33815.1.
AF158101 Genomic DNA. Translation: AAD42503.1.
PIRiS05559. GMBPT4.
RefSeqiNP_049856.1. NC_000866.4.

Genome annotation databases

GeneIDi1258623.
KEGGivg:1258623.

Similar proteinsi

Entry informationi

Entry nameiVG59_BPT4
AccessioniPrimary (citable) accession number: P13342
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: July 5, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references