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P13249

- PUAC_STRAD

UniProt

P13249 - PUAC_STRAD

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Protein

Puromycin N-acetyltransferase

Gene
pac
Organism
Streptomyces alboniger
Status
Reviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Detoxification of puromycin.

GO - Molecular functioni

  1. N-acetyltransferase activity Source: InterPro

GO - Biological processi

  1. response to antibiotic Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Antibiotic resistance

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-13983.

Names & Taxonomyi

Protein namesi
Recommended name:
Puromycin N-acetyltransferase (EC:2.3.-.-)
Gene namesi
Name:pac
OrganismiStreptomyces alboniger
Taxonomic identifieri132473 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 199199Puromycin N-acetyltransferasePRO_0000068578Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP13249.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 198193N-acetyltransferaseAdd
BLAST

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
[Graphical view]
PfamiPF00583. Acetyltransf_1. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P13249-1 [UniParc]FASTAAdd to Basket

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MTEYKPTVRL ATRDDVPRAV RTLAAAFADY PATRHTVDPD RHIERVTELQ    50
ELFLTRVGLD IGKVWVADDG AAVAVWTTPE SVEAGAVFAE IGPRMAELSG 100
SRLAAQQQME GLLAPHRPKE PAWFLATVGV SPDHQGKGLG SAVVLPGVEA 150
AERAGVPAFL ETSAPRNLPF YERLGFTVTA DVEVPEGPRT WCMTRKPGA 199
Length:199
Mass (Da):21,496
Last modified:February 1, 1996 - v2
Checksum:iBEDA36E20304DA35
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M25346 Genomic DNA. Translation: AAA64928.1.
PIRiJU0052.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M25346 Genomic DNA. Translation: AAA64928.1 .
PIRi JU0052.

3D structure databases

ProteinModelPortali P13249.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

BioCyci MetaCyc:MONOMER-13983.

Family and domain databases

Gene3Di 3.40.630.30. 1 hit.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
[Graphical view ]
Pfami PF00583. Acetyltransf_1. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
PROSITEi PS51186. GNAT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular analysis of the pac gene encoding a puromycin N-acetyl transferase from Streptomyces alboniger."
    Lacalle R.A., Pulido D., Vara J., Zalacain M., Jimenez A.
    Gene 79:375-380(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 12461 / DSM 40043 / JCM 4309 / NBRC 12738 / NCIMB 13007 / NRRL B-2403.

Entry informationi

Entry nameiPUAC_STRAD
AccessioniPrimary (citable) accession number: P13249
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: February 1, 1996
Last modified: April 16, 2014
This is version 64 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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