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P13249

- PUAC_STRAD

UniProt

P13249 - PUAC_STRAD

Protein

Puromycin N-acetyltransferase

Gene

pac

Organism
Streptomyces alboniger
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 2 (01 Feb 1996)
      Previous versions | rss
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    Functioni

    Detoxification of puromycin.

    GO - Molecular functioni

    1. N-acetyltransferase activity Source: InterPro

    GO - Biological processi

    1. response to antibiotic Source: UniProtKB-KW

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Antibiotic resistance

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-13983.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Puromycin N-acetyltransferase (EC:2.3.-.-)
    Gene namesi
    Name:pac
    OrganismiStreptomyces alboniger
    Taxonomic identifieri132473 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 199199Puromycin N-acetyltransferasePRO_0000068578Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP13249.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini6 – 198193N-acetyltransferasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 N-acetyltransferase domain.PROSITE-ProRule annotation

    Family and domain databases

    Gene3Di3.40.630.30. 1 hit.
    InterProiIPR016181. Acyl_CoA_acyltransferase.
    IPR000182. GNAT_dom.
    [Graphical view]
    PfamiPF00583. Acetyltransf_1. 1 hit.
    [Graphical view]
    SUPFAMiSSF55729. SSF55729. 1 hit.
    PROSITEiPS51186. GNAT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P13249-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTEYKPTVRL ATRDDVPRAV RTLAAAFADY PATRHTVDPD RHIERVTELQ    50
    ELFLTRVGLD IGKVWVADDG AAVAVWTTPE SVEAGAVFAE IGPRMAELSG 100
    SRLAAQQQME GLLAPHRPKE PAWFLATVGV SPDHQGKGLG SAVVLPGVEA 150
    AERAGVPAFL ETSAPRNLPF YERLGFTVTA DVEVPEGPRT WCMTRKPGA 199
    Length:199
    Mass (Da):21,496
    Last modified:February 1, 1996 - v2
    Checksum:iBEDA36E20304DA35
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M25346 Genomic DNA. Translation: AAA64928.1.
    PIRiJU0052.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M25346 Genomic DNA. Translation: AAA64928.1 .
    PIRi JU0052.

    3D structure databases

    ProteinModelPortali P13249.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    BioCyci MetaCyc:MONOMER-13983.

    Family and domain databases

    Gene3Di 3.40.630.30. 1 hit.
    InterProi IPR016181. Acyl_CoA_acyltransferase.
    IPR000182. GNAT_dom.
    [Graphical view ]
    Pfami PF00583. Acetyltransf_1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55729. SSF55729. 1 hit.
    PROSITEi PS51186. GNAT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular analysis of the pac gene encoding a puromycin N-acetyl transferase from Streptomyces alboniger."
      Lacalle R.A., Pulido D., Vara J., Zalacain M., Jimenez A.
      Gene 79:375-380(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 12461 / DSM 40043 / JCM 4309 / NBRC 12738 / NCIMB 13007 / NRRL B-2403.

    Entry informationi

    Entry nameiPUAC_STRAD
    AccessioniPrimary (citable) accession number: P13249
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 1, 1990
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 65 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3