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P13246

- AAC31_SALSP

UniProt

P13246 - AAC31_SALSP

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Protein

Aminoglycoside N(3')-acetyltransferase III

Gene
aacC3
Organism
Salmonella sp.
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Resistance to antibiotics containing the 2-deoxy-streptamine ring including gentamicin, kanamycin, tobramycin, neomycin and apramycin.

Catalytic activityi

Acetyl-CoA + a 2-deoxystreptamine antibiotic = CoA + N(3')-acetyl-2-deoxystreptamine antibiotic.

GO - Molecular functioni

  1. aminoglycoside 3-N-acetyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. response to antibiotic Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Antibiotic resistance

Names & Taxonomyi

Protein namesi
Recommended name:
Aminoglycoside N(3')-acetyltransferase III (EC:2.3.1.81)
Alternative name(s):
ACC(3)-III
Aminocyclitol 3-N-acetyltransferase type III
Gentamicin-(3)-N-acetyl-transferase
Gene namesi
Name:aacC3
Encoded oniPlasmid pWP113a0 Publication
OrganismiSalmonella sp.
Taxonomic identifieri599 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 286286Aminoglycoside N(3')-acetyltransferase IIIPRO_0000068543Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP13246.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR003679. Amioglycoside_AcTrfase.
[Graphical view]
PfamiPF02522. Antibiotic_NAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P13246-1 [UniParc]FASTAAdd to Basket

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MHTQKAITEA LQKLGVQSGD LLMVHASLKS IGPVEGGAET VVAALRSAVG    50
PTGTVMGYAS WDRSPYEETL NGARLDDNAR RTWPPFDPAT AGTYRGFGLL 100
NQFLVQAPGA RRSAHPDASM VAVGPLAETL TEPHELGHAL GEGSPNERFV 150
RLGGKALLLG APLNSVTALH YAEAVADIPN KRWVTYEMPM PGRDGEVAWK 200
TASDYDSNGI LDCFAIEGKQ DAVETIANAY VKLGRHREGV VGFAQCYLFD 250
AQDIVTFGVT YLEKHFGTTP IVPAHEAIER SCEPSG 286
Length:286
Mass (Da):30,631
Last modified:January 1, 1990 - v1
Checksum:i99194323A5DA56F9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X13543 Genomic DNA. Translation: CAA31895.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X13543 Genomic DNA. Translation: CAA31895.1 .

3D structure databases

ProteinModelPortali P13246.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR003679. Amioglycoside_AcTrfase.
[Graphical view ]
Pfami PF02522. Antibiotic_NAT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genes for gentamicin-(3)-N-acetyl-transferases III and IV. II. Nucleotide sequences of three AAC(3)-III genes and evolutionary aspects."
    Allmansberger R., Braeu B., Piepersberg W.
    Mol. Gen. Genet. 198:514-520(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiAAC31_SALSP
AccessioniPrimary (citable) accession number: P13246
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: April 16, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Plasmid

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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