Skip Header

Contribute Send feedback
Read comments (?) or add your own

P13129 (LUCI_LUCCR) Reviewed, UniProtKB/Swiss-Prot

Last modified June 28, 2011. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Luciferin 4-monooxygenase
Short name=Luciferase
EC=1.13.12.7
OrganismLuciola cruciata (Japanese firefly) (Genji firefly)
Taxonomic identifier7051 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Coleoptera › Polyphaga › Elateriformia › Elateroidea › Lampyridae › Luciolinae › Luciola

Protein attributes

Sequence length548 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Produces green light with a wavelength of 544 nm.

Catalytic activity

Photinus luciferin + O2 + ATP = oxidized Photinus luciferin + CO2 + AMP + diphosphate + light.

Cofactor

Magnesium.

Subcellular location

Peroxisome By similarity.

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family.

Ontologies

Keywords
   Biological processLuminescence
   Cellular componentPeroxisome
   LigandATP-binding
Magnesium
Metal-binding
Nucleotide-binding
   Molecular functionMonooxygenase
Oxidoreductase
Photoprotein
   Technical term3D-structure
Gene Ontology (GO)
   Biological processbioluminescence

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentperoxisome

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 548548Luciferin 4-monooxygenase
PRO_0000193143

Regions

Motif546 – 5483Microbody targeting signal Potential

Secondary structure

1 ................................................................................................ 548
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P13129 [UniParc].

Last modified January 1, 1990. Version 1.
Checksum: 2052D6189E79109F

FASTA54860,017
        10         20         30         40         50         60 
MENMENDENI VVGPKPFYPI EEGSAGTQLR KYMERYAKLG AIAFTNAVTG VDYSYAEYLE 

        70         80         90        100        110        120 
KSCCLGKALQ NYGLVVDGRI ALCSENCEEF FIPVIAGLFI GVGVAPTNEI YTLRELVHSL 

       130        140        150        160        170        180 
GISKPTIVFS SKKGLDKVIT VQKTVTTIKT IVILDSKVDY RGYQCLDTFI KRNTPPGFQA 

       190        200        210        220        230        240 
SSFKTVEVDR KEQVALIMNS SGSTGLPKGV QLTHENTVTR FSHARDPIYG NQVSPGTAVL 

       250        260        270        280        290        300 
TVVPFHHGFG MFTTLGYLIC GFRVVMLTKF DEETFLKTLQ DYKCTSVILV PTLFAILNKS 

       310        320        330        340        350        360 
ELLNKYDLSN LVEIASGGAP LSKEVGEAVA RRFNLPGVRQ GYGLTETTSA IIITPEGDDK 

       370        380        390        400        410        420 
PGASGKVVPL FKAKVIDLDT KKSLGPNRRG EVCVKGPMLM KGYVNNPEAT KELIDEEGWL 

       430        440        450        460        470        480 
HTGDIGYYDE EKHFFIVDRL KSLIKYKGYQ VPPAELESVL LQHPSIFDAG VAGVPDPVAG 

       490        500        510        520        530        540 
ELPGAVVVLE SGKNMTEKEV MDYVASQVSN AKRLRGGVRF VDEVPKGLTG KIDGRAIREI 


LKKPVAKM

« Hide

References

[1]"Cloning and sequence analysis of cDNA for luciferase of a Japanese firefly, Luciola cruciata."
Masuda T., Tatsumi H., Nakano E.
Gene 77:265-270(1989) [PubMed: 2473944] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		M26194 mRNA. Translation: AAA29135.1.
PIRJS0181.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2D1QX-ray2.30A1-548[»]
2D1RX-ray1.60A1-548[»]
2D1SX-ray1.30A1-548[»]
2D1TX-ray1.45A4-548[»]
ProteinModelPortalP13129.
SMRP13129. Positions 7-545.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamPF00501. AMP-binding. 1 hit.
[Graphical view]
PROSITEPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLUCI_LUCCR
AccessionPrimary (citable) accession number: P13129
Entry history
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: January 1, 1990
Last modified: June 28, 2011
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents