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Protein

Leukopyrokinin

Gene
N/A
Organism
Rhyparobia maderae (Madeira cockroach) (Leucophaea maderae)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Mediates visceral muscle contractile activity (myotropic activity).

Miscellaneous

An analog without the N-terminal PCA residue was synthesized and found to exhibit greater activity (144%) than the parent neuropeptide. The portion of the sequence of LPK most critical for the myotropic properties is limited to the pentapeptide fragment FTPRL.

GO - Biological processi

Keywordsi

Molecular functionNeuropeptide

Names & Taxonomyi

Protein namesi
Recommended name:
Leukopyrokinin
Short name:
LPK
Alternative name(s):
Lem-PK
OrganismiRhyparobia maderae (Madeira cockroach) (Leucophaea maderae)
Taxonomic identifieri36963 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraPolyneopteraDictyopteraBlattodeaBlaberoideaBlaberidaeOxyhaloinaeRhyparobia

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00000443191 – 8Leukopyrokinin8

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1Pyrrolidone carboxylic acid1 Publication1
Modified residuei8Leucine amide1 Publication1

Keywords - PTMi

Amidation, Pyrrolidone carboxylic acid

Family & Domainsi

Sequence similaritiesi

Belongs to the pyrokinin family.Curated

Family and domain databases

PROSITEiView protein in PROSITE
PS00539. PYROKININ. 1 hit.

Sequencei

Sequence statusi: Complete.

Length:8
Mass (Da):949
Last modified:February 1, 1994 - v3
Checksum:i92341771A9D5A1B6
GO

Sequence databases

PIRiA23967.

Entry informationi

Entry nameiLPK_RHYMA
AccessioniPrimary (citable) accession number: P13049
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: February 1, 1994
Last modified: August 30, 2017
This is version 59 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families