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Protein

Protein FdhE

Gene

fdhE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Necessary for formate dehydrogenase activity.

GO - Molecular functioni

  • ferric iron binding Source: EcoCyc

GO - Biological processi

  • protein maturation Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG10284-MONOMER.
ECOL316407:JW3862-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FdhE
Gene namesi
Name:fdhE
Ordered Locus Names:b3891, JW3862
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10284. fdhE.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: EcoCyc
  • cytosol Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 309309Protein FdhEPRO_0000189638Add
BLAST

Proteomic databases

EPDiP13024.
PaxDbiP13024.
PRIDEiP13024.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
fdnGP241834EBI-550129,EBI-550115
fdoGP321763EBI-550129,EBI-368676

Protein-protein interaction databases

BioGridi4261097. 6 interactions.
DIPiDIP-9571N.
IntActiP13024. 23 interactions.
MINTiMINT-1292317.
STRINGi511145.b3891.

Structurei

3D structure databases

ProteinModelPortaliP13024.
SMRiP13024. Positions 23-306.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FdhE family.Curated

Phylogenomic databases

eggNOGiENOG4105F46. Bacteria.
COG3058. LUCA.
HOGENOMiHOG000163613.
InParanoidiP13024.
KOiK02380.
OMAiLDQPGLC.
PhylomeDBiP13024.

Family and domain databases

Gene3Di3.90.1670.10. 1 hit.
HAMAPiMF_00611. FdeH. 1 hit.
InterProiIPR024064. FdhE-like.
IPR006452. Formate_DH_accessory.
[Graphical view]
PfamiPF04216. FdhE. 1 hit.
[Graphical view]
PIRSFiPIRSF018296. Format_dh_formtn. 1 hit.
SUPFAMiSSF144020. SSF144020. 1 hit.
TIGRFAMsiTIGR01562. FdhE. 1 hit.

Sequencei

Sequence statusi: Complete.

P13024-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIRIIPQDE LGSSEKRTAD MIPPLLFPRL KNLYNRRAER LRELAENNPL
60 70 80 90 100
GDYLRFAALI AHAQEVVLYD HPLEMDLTAR IKEASAQGKP PLDIHVLPRD
110 120 130 140 150
KHWQKLLMAL IAELKPEMSG PALAVIENLE KASTQELEDM ASALFASDFS
160 170 180 190 200
SVSSDKAPFI WAALSLYWAQ MANLIPGKAR AEYGEQRQYC PVCGSMPVSS
210 220 230 240 250
MVQIGTTQGL RYLHCNLCET EWHVVRVKCS NCEQSGKLHY WSLDDEQAAI
260 270 280 290 300
KAESCDDCDT YLKILYQEKD PKIEAVADDL ASLVLDARME QEGYARSSIN

PFLFPGEGE
Length:309
Mass (Da):34,747
Last modified:October 1, 1993 - v2
Checksum:iF9A0B30CC980D6E6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti57 – 571A → R in CAA34149 (PubMed:1995428).Curated
Sequence conflicti177 – 20832GKARA…IGTTQ → AKPALNTASNVNIARFVVLC RCPAWCKLAPLR in CAA34149 (PubMed:1995428).CuratedAdd
BLAST
Sequence conflicti291 – 2911Q → E in CAA34149 (PubMed:1995428).Curated
Sequence conflicti296 – 30914RSSIN…PGEGE → AVPSTRSCFRVKESNL in CAA34149 (PubMed:1995428).CuratedAdd
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X16016 Genomic DNA. Translation: CAA34149.1.
L19201 Genomic DNA. Translation: AAB03024.1.
U00096 Genomic DNA. Translation: AAD13453.1.
AP009048 Genomic DNA. Translation: BAE77418.1.
PIRiS40835.
RefSeqiNP_418327.1. NC_000913.3.
WP_000027703.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAD13453; AAD13453; b3891.
BAE77418; BAE77418; BAE77418.
GeneIDi948384.
KEGGiecj:JW3862.
eco:b3891.
PATRICi32123289. VBIEscCol129921_4005.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X16016 Genomic DNA. Translation: CAA34149.1.
L19201 Genomic DNA. Translation: AAB03024.1.
U00096 Genomic DNA. Translation: AAD13453.1.
AP009048 Genomic DNA. Translation: BAE77418.1.
PIRiS40835.
RefSeqiNP_418327.1. NC_000913.3.
WP_000027703.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP13024.
SMRiP13024. Positions 23-306.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261097. 6 interactions.
DIPiDIP-9571N.
IntActiP13024. 23 interactions.
MINTiMINT-1292317.
STRINGi511145.b3891.

Proteomic databases

EPDiP13024.
PaxDbiP13024.
PRIDEiP13024.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD13453; AAD13453; b3891.
BAE77418; BAE77418; BAE77418.
GeneIDi948384.
KEGGiecj:JW3862.
eco:b3891.
PATRICi32123289. VBIEscCol129921_4005.

Organism-specific databases

EchoBASEiEB0280.
EcoGeneiEG10284. fdhE.

Phylogenomic databases

eggNOGiENOG4105F46. Bacteria.
COG3058. LUCA.
HOGENOMiHOG000163613.
InParanoidiP13024.
KOiK02380.
OMAiLDQPGLC.
PhylomeDBiP13024.

Enzyme and pathway databases

BioCyciEcoCyc:EG10284-MONOMER.
ECOL316407:JW3862-MONOMER.

Miscellaneous databases

PROiP13024.

Family and domain databases

Gene3Di3.90.1670.10. 1 hit.
HAMAPiMF_00611. FdeH. 1 hit.
InterProiIPR024064. FdhE-like.
IPR006452. Formate_DH_accessory.
[Graphical view]
PfamiPF04216. FdhE. 1 hit.
[Graphical view]
PIRSFiPIRSF018296. Format_dh_formtn. 1 hit.
SUPFAMiSSF144020. SSF144020. 1 hit.
TIGRFAMsiTIGR01562. FdhE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFDHE_ECOLI
AccessioniPrimary (citable) accession number: P13024
Secondary accession number(s): Q2M8I8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: October 1, 1993
Last modified: September 7, 2016
This is version 130 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.