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Protein

Protein FdhE

Gene

fdhE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Necessary for formate dehydrogenase activity.

GO - Molecular functioni

  • ferric iron binding Source: EcoCyc

GO - Biological processi

  • protein maturation Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:EG10284-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FdhE
Gene namesi
Name:fdhE
Ordered Locus Names:b3891, JW3862
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10284 fdhE

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: EcoCyc
  • cytosol Source: EcoCyc

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001896381 – 309Protein FdhEAdd BLAST309

Proteomic databases

EPDiP13024
PaxDbiP13024
PRIDEiP13024

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi426109713 interactors.
DIPiDIP-9571N
IntActiP13024 26 interactors.
MINTiP13024
STRINGi316385.ECDH10B_4081

Structurei

3D structure databases

ProteinModelPortaliP13024
SMRiP13024
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FdhE family.Curated

Phylogenomic databases

eggNOGiENOG4105F46 Bacteria
COG3058 LUCA
HOGENOMiHOG000163613
InParanoidiP13024
KOiK02380
OMAiLDQPGLC
PhylomeDBiP13024

Family and domain databases

CDDicd16341 FdhE, 1 hit
Gene3Di3.90.1670.101 hit
HAMAPiMF_00611 FdeH, 1 hit
InterProiView protein in InterPro
IPR024064 FdhE-like_sf
IPR006452 Formate_DH_accessory
PANTHERiPTHR37689 PTHR37689, 1 hit
PfamiView protein in Pfam
PF04216 FdhE, 1 hit
PIRSFiPIRSF018296 Format_dh_formtn, 1 hit
SUPFAMiSSF144020 SSF144020, 1 hit
TIGRFAMsiTIGR01562 FdhE, 1 hit

Sequencei

Sequence statusi: Complete.

P13024-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIRIIPQDE LGSSEKRTAD MIPPLLFPRL KNLYNRRAER LRELAENNPL
60 70 80 90 100
GDYLRFAALI AHAQEVVLYD HPLEMDLTAR IKEASAQGKP PLDIHVLPRD
110 120 130 140 150
KHWQKLLMAL IAELKPEMSG PALAVIENLE KASTQELEDM ASALFASDFS
160 170 180 190 200
SVSSDKAPFI WAALSLYWAQ MANLIPGKAR AEYGEQRQYC PVCGSMPVSS
210 220 230 240 250
MVQIGTTQGL RYLHCNLCET EWHVVRVKCS NCEQSGKLHY WSLDDEQAAI
260 270 280 290 300
KAESCDDCDT YLKILYQEKD PKIEAVADDL ASLVLDARME QEGYARSSIN

PFLFPGEGE
Length:309
Mass (Da):34,747
Last modified:October 1, 1993 - v2
Checksum:iF9A0B30CC980D6E6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti57A → R in CAA34149 (PubMed:1995428).Curated1
Sequence conflicti177 – 208GKARA…IGTTQ → AKPALNTASNVNIARFVVLC RCPAWCKLAPLR in CAA34149 (PubMed:1995428).CuratedAdd BLAST32
Sequence conflicti291Q → E in CAA34149 (PubMed:1995428).Curated1
Sequence conflicti296 – 309RSSIN…PGEGE → AVPSTRSCFRVKESNL in CAA34149 (PubMed:1995428).CuratedAdd BLAST14

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X16016 Genomic DNA Translation: CAA34149.1
L19201 Genomic DNA Translation: AAB03024.1
U00096 Genomic DNA Translation: AAD13453.1
AP009048 Genomic DNA Translation: BAE77418.1
PIRiS40835
RefSeqiNP_418327.1, NC_000913.3
WP_000027703.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAD13453; AAD13453; b3891
BAE77418; BAE77418; BAE77418
GeneIDi948384
KEGGiecj:JW3862
eco:b3891
PATRICifig|1411691.4.peg.2818

Similar proteinsi

Entry informationi

Entry nameiFDHE_ECOLI
AccessioniPrimary (citable) accession number: P13024
Secondary accession number(s): Q2M8I8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: October 1, 1993
Last modified: March 28, 2018
This is version 142 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome