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Protein

UPF0098 protein YbhB

Gene

ybhB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG11238-MONOMER.
ECOL316407:JW0756-MONOMER.
RETL1328306-WGS:GSTH-297-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0098 protein YbhB
Gene namesi
Name:ybhB
Ordered Locus Names:b0773, JW0756
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11238. ybhB.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 158158UPF0098 protein YbhBPRO_0000137900Add
BLAST

Proteomic databases

PaxDbiP12994.
PRIDEiP12994.

Interactioni

Subunit structurei

Homodimer.

Protein-protein interaction databases

BioGridi4261840. 25 interactions.
IntActiP12994. 6 interactions.
STRINGi511145.b0773.

Structurei

Secondary structure

1
158
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi2 – 43Combined sources
Helixi16 – 183Combined sources
Beta strandi34 – 374Combined sources
Beta strandi45 – 528Combined sources
Turni56 – 594Combined sources
Beta strandi61 – 7010Combined sources
Helixi80 – 823Combined sources
Beta strandi99 – 1024Combined sources
Beta strandi114 – 12613Combined sources
Helixi136 – 14611Combined sources
Beta strandi147 – 15711Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1FJJX-ray1.66A1-158[»]
1VI3X-ray1.76A2-158[»]
ProteinModelPortaliP12994.
SMRiP12994. Positions 1-158.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP12994.

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0098 family.Curated

Phylogenomic databases

eggNOGiENOG4108V1U. Bacteria.
COG1881. LUCA.
HOGENOMiHOG000236247.
InParanoidiP12994.
KOiK06910.
OMAiWHWIVAN.
OrthoDBiEOG6N681K.
PhylomeDBiP12994.

Family and domain databases

Gene3Di3.90.280.10. 1 hit.
InterProiIPR008914. PtdEtn-bd_prot_PEBP.
IPR005247. YbhB_YbcL.
[Graphical view]
PfamiPF01161. PBP. 1 hit.
[Graphical view]
SUPFAMiSSF49777. SSF49777. 1 hit.
TIGRFAMsiTIGR00481. TIGR00481. 1 hit.

Sequencei

Sequence statusi: Complete.

P12994-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLISNDLRD GDKLPHRHVF NGMGYDGDNI SPHLAWDDVP AGTKSFVVTC
60 70 80 90 100
YDPDAPTGSG WWHWVVVNLP ADTRVLPQGF GSGLVAMPDG VLQTRTDFGK
110 120 130 140 150
TGYDGAAPPK GETHRYIFTV HALDIERIDV DEGASGAMVG FNVHFHSLAS

ASITAMFS
Length:158
Mass (Da):17,085
Last modified:November 1, 1997 - v2
Checksum:i0AD6F21157060A4C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti136 – 1361G → A in AAA23513 (PubMed:3058702).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J04423 Genomic DNA. Translation: AAA23513.1.
U00096 Genomic DNA. Translation: AAC73860.1.
AP009048 Genomic DNA. Translation: BAE76360.1.
PIRiE64813. Q3ECBA.
RefSeqiNP_415294.1. NC_000913.3.
WP_000767389.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73860; AAC73860; b0773.
BAE76360; BAE76360; BAE76360.
GeneIDi945383.
KEGGiecj:JW0756.
eco:b0773.
PATRICi32116747. VBIEscCol129921_0799.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J04423 Genomic DNA. Translation: AAA23513.1.
U00096 Genomic DNA. Translation: AAC73860.1.
AP009048 Genomic DNA. Translation: BAE76360.1.
PIRiE64813. Q3ECBA.
RefSeqiNP_415294.1. NC_000913.3.
WP_000767389.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1FJJX-ray1.66A1-158[»]
1VI3X-ray1.76A2-158[»]
ProteinModelPortaliP12994.
SMRiP12994. Positions 1-158.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261840. 25 interactions.
IntActiP12994. 6 interactions.
STRINGi511145.b0773.

Proteomic databases

PaxDbiP12994.
PRIDEiP12994.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73860; AAC73860; b0773.
BAE76360; BAE76360; BAE76360.
GeneIDi945383.
KEGGiecj:JW0756.
eco:b0773.
PATRICi32116747. VBIEscCol129921_0799.

Organism-specific databases

EchoBASEiEB1220.
EcoGeneiEG11238. ybhB.

Phylogenomic databases

eggNOGiENOG4108V1U. Bacteria.
COG1881. LUCA.
HOGENOMiHOG000236247.
InParanoidiP12994.
KOiK06910.
OMAiWHWIVAN.
OrthoDBiEOG6N681K.
PhylomeDBiP12994.

Enzyme and pathway databases

BioCyciEcoCyc:EG11238-MONOMER.
ECOL316407:JW0756-MONOMER.
RETL1328306-WGS:GSTH-297-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP12994.
PROiP12994.

Family and domain databases

Gene3Di3.90.280.10. 1 hit.
InterProiIPR008914. PtdEtn-bd_prot_PEBP.
IPR005247. YbhB_YbcL.
[Graphical view]
PfamiPF01161. PBP. 1 hit.
[Graphical view]
SUPFAMiSSF49777. SSF49777. 1 hit.
TIGRFAMsiTIGR00481. TIGR00481. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The Escherichia coli biotin biosynthetic enzyme sequences predicted from the nucleotide sequence of the bio operon."
    Otsuka A.J., Buoncristiani M.R., Howard P.K., Flamm J., Johnson O., Yamamoto R., Uchida K., Cook C., Ruppert J., Matsuzaki J.
    J. Biol. Chem. 263:19577-19585(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Crystal structures of YBHB and YBCL from Escherichia coli, two bacterial homologues to a Raf kinase inhibitor protein."
    Serre L., Pereira de Jesus K., Zelwer C., Bureaud N., Schoentgen F., Benedetti H.
    J. Mol. Biol. 310:617-634(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.66 ANGSTROMS), CHARACTERIZATION.

Entry informationi

Entry nameiYBHB_ECOLI
AccessioniPrimary (citable) accession number: P12994
Secondary accession number(s): P75766, Q2MBJ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 1, 1990
Last sequence update: November 1, 1997
Last modified: January 20, 2016
This is version 126 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.