P12867 (XYLB_ACTM4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Xylulose kinase
Short name=Xylulokinase
EC=2.7.1.17

Gene names

Name:	xylB
Ordered Locus Names:	AMIS_10360

Organism

Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB 12654 / NBRC 102363 / 431) [Complete proteome] [HAMAP]

Taxonomic identifier

512565 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Actinoplanes › Actinoplanes missouriensis

Protein attributes

Sequence length	466 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + D-xylulose = ADP + D-xylulose 5-phosphate.
Sequence similarities	Belongs to the FGGY kinase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Xylose metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-xylose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW xylulose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW xylulokinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 466	466	Xylulose kinase		PRO_0000059545
Experimental info
	Sequence conflict	60 – 61	2	DD → EF in CAA34165. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P12867 [UniParc]. Last modified September 5, 2012. Version 3. Checksum: 8FA3AFD953F03739	FASTA	466	47,866
	10 20 30 40 50 60 MALVAGIDSS TQSCKVVIRD AETGALVRQG RASHPDGTEV HPDAWWSALQ SAIEEAGGLD 70 80 90 100 110 120 DVAAASVAGQ QHGMVALDEN GEVVRPALLW NDTRSAGAAA DLIAELGGGE KWAEAVGIVP 130 140 150 160 170 180 VASFTLTKLR WLARNEPANA AKVAAVCLPH DWLTWKLSGS TDIADIKTDR SDASGTLYWS 190 200 210 220 230 240 AKTNEYRRDL LELGFGRDLV LPEVLGPTGI AGHLPNGAPL GPGAGDNAAA ALGTGALPGD 250 260 270 280 290 300 VIVSIGTSGT VFVSSDVAPV DGRGTVAGFA DTTGRFLPIV VTLNAARVLD AAAKLLGVDH 310 320 330 340 350 360 DELSRLALSA PAGADGMVLV PYLEGERTPN RPDATGAIHG LTLKTSDPAH LARAAVEGML 370 380 390 400 410 420 CALADGLDAL VAHGAEANRI VLVGGGARSE AVRRIAPALF GKPVLVPPPG EYVADGAARQ 430 440 450 460 AAWVARGGDT PPAWSAASPE VYEDDPVPLI REQYAAAQNA VIDRTR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Actinoplanes missouriensis 431 (= NBRC 102363)." Ohnishi Y., Ishikawa J., Sekine M., Hosoyama A., Harada T., Narita H., Hata T., Konno Y., Tutikane K., Fujita N., Horinouchi S., Hayakawa M. Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB 12654 / NBRC 102363 / 431.
[2]	"Xylose isomerase from Actinoplanes missouriensis: primary structure of the gene and the protein." Amore R., Hollenberg C.P. Nucleic Acids Res. 17:7515-7515(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-61. Strain: ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB 12654 / NBRC 102363 / 431.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP012319 Genomic DNA. Translation: BAL86256.1. X16042 Genomic DNA. Translation: CAA34165.1.
PIR	S05999.
RefSeq	YP_005460772.1. NC_017093.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAL86256; BAL86256; AMIS_10360.
GeneID	12051266.
KEGG	ams:AMIS_10360.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K00854.
Family and domain databases
InterPro	IPR018485. Carb_kinase_FGGY_C. IPR018483. Carb_kinase_FGGY_CS. IPR018484. Carb_kinase_FGGY_N. IPR006000. Xylulokinase. [Graphical view]
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01312. XylB. 1 hit.
PROSITE	PS00933. FGGY_KINASES_1. 1 hit. PS00445. FGGY_KINASES_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYLB_ACTM4

Accession

Primary (citable) accession number: P12867
Secondary accession number(s): I0GZR9

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1989
Last sequence update:	September 5, 2012
Last modified:	April 3, 2013
This is version 56 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program