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Protein

ADP,ATP carrier protein 2, mitochondrial

Gene

ANT2

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.

Miscellaneous

The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. At least 2 of the odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei160NucleotideBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
ADP,ATP carrier protein 2, mitochondrial
Alternative name(s):
ADP/ATP translocase 2
Adenine nucleotide translocator 2
Short name:
ANT 2
Gene namesi
Name:ANT2
Synonyms:ANT-G2
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Chromosome 4

Organism-specific databases

MaizeGDBi17145.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei84 – 118Helical; Name=1By similarityAdd BLAST35
Transmembranei155 – 179Helical; Name=2By similarityAdd BLAST25
Transmembranei188 – 222Helical; Name=3By similarityAdd BLAST35
Transmembranei257 – 284Helical; Name=4By similarityAdd BLAST28
Transmembranei289 – 323Helical; Name=5By similarityAdd BLAST35
Transmembranei352 – 377Helical; Name=6By similarityAdd BLAST26

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 77MitochondrionSequence analysisAdd BLAST77
ChainiPRO_000001924978 – 387ADP,ATP carrier protein 2, mitochondrialAdd BLAST310

Proteomic databases

PaxDbiP12857.
PRIDEiP12857.

Expressioni

Gene expression databases

ExpressionAtlasiP12857. baseline.
GenevisibleiP12857. ZM.

Interactioni

Subunit structurei

Homodimer.

Protein-protein interaction databases

STRINGi4577.GRMZM2G135186_P03.

Structurei

3D structure databases

ProteinModelPortaliP12857.
SMRiP12857.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati85 – 178Solcar 1Add BLAST94
Repeati190 – 282Solcar 2Add BLAST93
Repeati290 – 376Solcar 3Add BLAST87

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi317 – 322Substrate recognitionBy similarity6

Sequence similaritiesi

Keywords - Domaini

Repeat, Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0749. Eukaryota.
ENOG410XNW0. LUCA.
KOiK05863.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002113. Aden_trnslctor.
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00927. ADPTRNSLCASE.
PR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P12857-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADQANQPTV LHKLGGQFHL SSSFSEGVRA RNICPSFSPY ERRFATRNYM
60 70 80 90 100
TQSLWGPSMS VSGGINVPVM PTPLFANAPA EKGGKNFMID FMMGGVSAAV
110 120 130 140 150
SKTAAAPIER VKLLIQNQDE MIKSGRLSEP YKGIADCFKR TIKDEGFSSL
160 170 180 190 200
WRGNTANVIR YFPTQALNFA FKDYFKRLFN FKKDRDGYWK WFAGNLASGG
210 220 230 240 250
AAGASSLFFV YSLDYARTRL ANDAKAAKGG GDRQFNGLVD VYRKTLKSDG
260 270 280 290 300
IAGLYRGFNI SCVGIIVYRG LYFGLYDSIK PVVLTGSLQD NFFASFALGW
310 320 330 340 350
LITNGAGLAS YPIDTVRRRM MMTSGEAVKY KSSLDAFQQI LKKEGPKSLF
360 370 380
KGAGANILRA IAGAGVLSGY DQLQILFFGK KYGSGGA
Length:387
Mass (Da):42,333
Last modified:August 1, 1992 - v2
Checksum:i020E616DC5EC2664
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti242Y → I in CAA33743 (PubMed:2547608).Curated1
Sequence conflicti327A → G in CAA33743 (PubMed:2547608).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59086 mRNA. Translation: CAA41812.1.
X15712 Genomic DNA. Translation: CAA33743.1.
PIRiS16568.
RefSeqiNP_001105434.1. NM_001111964.1.
XP_008677791.1. XM_008679569.1.
UniGeneiZm.75.

Genome annotation databases

EnsemblPlantsiZm00001d051685_T001; Zm00001d051685_P001; Zm00001d051685.
Zm00001d051685_T002; Zm00001d051685_P002; Zm00001d051685.
GeneIDi542389.
GrameneiZm00001d051685_T001; Zm00001d051685_P001; Zm00001d051685.
Zm00001d051685_T002; Zm00001d051685_P002; Zm00001d051685.
KEGGizma:542389.

Similar proteinsi

Entry informationi

Entry nameiADT2_MAIZE
AccessioniPrimary (citable) accession number: P12857
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: August 1, 1992
Last modified: August 30, 2017
This is version 122 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families