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Protein

Phosphoglycerate kinase, cytosolic

Gene
N/A
Organism
Triticum aestivum (Wheat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase, cytosolic
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase (TRAES_3BF026900020CFD_c1), Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase (PK), Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase (TRAES_3BF028500040CFD_c1), Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase, Pyruvate kinase
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei41SubstrateBy similarity1
Binding sitei122SubstrateBy similarity1
Binding sitei155SubstrateBy similarity1
Binding sitei206ATPBy similarity1
Binding sitei297ATP; via carbonyl oxygenBy similarity1
Binding sitei328ATPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi357 – 360ATPBy similarity4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase, cytosolic (EC:2.7.2.3)
OrganismiTriticum aestivum (Wheat)
Taxonomic identifieri4565 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeTriticinaeTriticum
Proteomesi
  • UP000019116 Componenti: Unplaced

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001458721 – 401Phosphoglycerate kinase, cytosolicAdd BLAST401

Proteomic databases

PRIDEiP12783

Expressioni

Gene expression databases

ExpressionAtlasiP12783 baseline and differential

Interactioni

Subunit structurei

Monomer.

Structurei

3D structure databases

ProteinModelPortaliP12783
SMRiP12783
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni25 – 27Substrate bindingBy similarity3
Regioni64 – 67Substrate bindingBy similarity4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.Curated

Phylogenomic databases

OMAiVESMRIG

Family and domain databases

CDDicd00318 Phosphoglycerate_kinase, 1 hit
Gene3Di3.40.50.1260, 3 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015911 Phosphoglycerate_kinase_CS
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit
PROSITEiView protein in PROSITE
PS00111 PGLYCERATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

P12783-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATKRSVGTL GEADLKGKKV FVRADLNVPL DDAQKITDDT RIRASIPTIK
60 70 80 90 100
YLLEKGAKVI LASHLGRPKG VTPKFSLKPL VARLSELLGL EVVMAPDCIG
110 120 130 140 150
EEVEKLAAAL PDGGVLLLEN VRFYKEEEKN DPEFAKKLAS VADLYVNDAF
160 170 180 190 200
GTAHRAHAST EGVTKFLRPS VAGFLMQKEL DYLVGAVANP KKPFAAIVGG
210 220 230 240 250
SKVSSKIGVI ESLLAKVDIL ILGGGMIFTF YKAQGLAVGK SLVEEDKLEL
260 270 280 290 300
ATSLIETAKS KGVKLLLPTD VVVADKFAAD AESKIVPATA IPDGWMGLDV
310 320 330 340 350
GPDSIKTFAE ALDTTKTVIW NGPMGVFEFE KFAAGTDAIA KQLAELTGKG
360 370 380 390 400
VTTIIGGGDS VAAVEKAGLA DKMSHISTGG GASLELLEGK PLPGVLALDE

A
Length:401
Mass (Da):42,122
Last modified:October 1, 1989 - v1
Checksum:iDF35346175CEB3F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15232 mRNA Translation: CAA33302.1
PIRiS05966 TVWTGY
UniGeneiTa.54263

Genome annotation databases

EnsemblPlantsiTRIAE_CS42_6BS_TGACv1_513938_AA1652520.2; TRIAE_CS42_6BS_TGACv1_513938_AA1652520.2; TRIAE_CS42_6BS_TGACv1_513938_AA1652520
GrameneiTRIAE_CS42_6BS_TGACv1_513938_AA1652520.2; TRIAE_CS42_6BS_TGACv1_513938_AA1652520.2; TRIAE_CS42_6BS_TGACv1_513938_AA1652520

Similar proteinsi

Entry informationi

Entry nameiPGKY_WHEAT
AccessioniPrimary (citable) accession number: P12783
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: October 1, 1989
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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