Reviewed, UniProtKB/Swiss-Prot P12540 (PIVA2_ADE12)

Names and origin

Protein names

Recommended name:
    Maturation protein
Alternative name(s):
    Protein IVa2

Gene names

Name:

PIVA2

Organism

Human adenovirus A serotype 12 (HAdV-12) (Human adenovirus 12)

Taxonomic identifier

28282 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Adenoviridae › Mastadenovirus › Human adenovirus A

Virus host

Homo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the adenoviridae protein IVa2 family.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Gene Ontology (GO)
Biological process	viral transcription Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 452	452	Maturation protein		PRO_0000221886
Regions
	Nucleotide binding	171 – 178	8	ATP Potential
Experimental info
	Sequence conflict	1 – 7	7	MLPCRST → METQ Ref.2
	Sequence conflict	51 – 52	2	QN → HD Ref.2
	Sequence conflict	115 – 116	2	FK → LQ Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P12540-1 [UniParc]. Last modified June 1, 1994. Version 2. Checksum: 6AE58DB038C8E9C8	FASTA	452	51,545
	10 20 30 40 50 60 MLPCRSTGRR HALQHQPPQF KAHTGQRSTR SASIHRDRNN PDAHITSLEG QNPRPFGCSP 70 80 90 100 110 120 PRSLQQQPAK PPQRGSLLDR DGIENITELW DRLQLLKQTL DHMPMADGLK PLKNFKSLQE 130 140 150 160 170 180 LLSLGGERLL GELAKQNIRV RQMMNEVAPL LHEDGSCTSL NYHLQPVIGV IYGPTGCGKS 190 200 210 220 230 240 QLLRNLLSAQ LVTPAPETVF FIVPQVDMIP PSEIKSWEMQ ICEGNYVPGP EGTIIPQSGT 250 260 270 280 290 300 LCPKFVKLSY DDLTLDHNYD VSDPENIFAQ AAARGPIAII MDECMENLGS HKGVSKFFHA 310 320 330 340 350 360 FPSKLHDKFP KCTGYTVFVV LHNMNPRRDL AGNIANLKIQ SKLHIMSPRM HPTQLNRFIN 370 380 390 400 410 420 TYTKGLPLAI SLLLKDIFNH HAQRCCYDWI IYNTNPEHEA LQWSYLHPKD GLMPMYLNIQ 430 440 450 AHLYKILEHI HRVLNDRERW SRAYHVRKNK YQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequence of human adenovirus type 12 DNA: comparative functional analysis." Sprengel J., Schmitz B., Heuss-Neitzel D., Zock C., Doerfler W. J. Virol. 68:379-389(1994) [PubMed: 8254750] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Nucleotide sequence of the genes encoded in early region 2b of human adenovirus type 12." Shu L., Hong J.S., Wei Y.-F., Engler J.A. Gene 46:187-195(1986) [PubMed: 3803925] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-123.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X73487 Genomic DNA. Translation: CAA51881.1. M14785 Genomic DNA. No translation available.
PIR	S33932.
RefSeq	NP_040914.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1460856.
Family and domain databases
InterPro	IPR003389. Adeno_IVa2. [Graphical view]
Pfam	PF02456. Adeno_IVa2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PIVA2_ADE12

Accession

Primary (citable) accession number: P12540

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1989
Last sequence update:	June 1, 1994
Last modified:	July 28, 2009
This is version 37 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Virus (Virus annotation project)