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Reviewed, UniProtKB/Swiss-Prot P12345 (AATM_RABIT)

Last modified June 16, 2009. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Aspartate aminotransferase, mitochondrial
    EC=2.6.1.1
Alternative name(s):
    mAspAT
    Transaminase A
    Glutamate oxaloacetate transaminase 2
    Fatty acid-binding protein
    FABP-1
    FABPpm
Gene names
Name: GOT2
OrganismOryctolagus cuniculus (Rabbit)
Taxonomic identifier9986 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus

Protein attributes

Sequence length30 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Facilitates cellular uptake of long-chain free fatty acids By similarity.

Catalytic activity

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.

Cofactor

Pyridoxal phosphate.

Subunit structure

Homodimer.

Subcellular location

Mitochondrion matrix. Cell membrane By similarity.

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

Sequence similarities

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›30›30Aspartate aminotransferase, mitochondrial
PRO_0000123886

Experimental info

Non-terminal residue301

Sequences

Sequence LengthMass (Da)Tools
P12345-1 [UniParc].

Last modified October 1, 1989. Version 1.
Checksum: 410321530B95B673

FASTA303,401
        10         20         30 
SSWWAHVEMG PPDPILGVTE AYKRDTNSKK 

« Hide

References

[1]"Aspartate aminotransferase isozymes from rabbit liver. Purification and properties."
Kuramitsu S., Inoue K., Kondo K., Aki K., Kagamiyama H.
J. Biochem. 97:1337-1345(1985) [PubMed: 4030726] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Liver.

Cross-references

Sequence databases

PIRB27103.

3D structure databases

HSSPHSSP built from PDB template 7AAT based on UniProtKB P00508.
ModBaseSearch...

Genome annotation databases

EnsemblENSOCUG00000003871. Oryctolagus cuniculus. [Contig view]

Phylogenomic databases

HOVERGENP12345.

Enzyme and pathway databases

BRENDA2.6.1.1. 255.

Family and domain databases

InterProIPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
[Graphical view]
PANTHERPTHR11879. Asp_trans. 1 hit.
PROSITEPS00105. AA_TRANSFER_CLASS_1. Partial match.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAATM_RABIT
AccessionPrimary (citable) accession number: P12345
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: October 1, 1989
Last modified: June 16, 2009
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents