P12310 (DHG_BACSU) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 100.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Glucose 1-dehydrogenase EC=1.1.1.47 | ||||
| Gene names |
| ||||
| Organism | Bacillus subtilis (strain 168) [Reference proteome] [HAMAP] | ||||
| Taxonomic identifier | 224308 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › ![]() |
Protein attributes
| Sequence length | 261 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Catalytic activity | Beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H. |
| Subunit structure | Homotetramer. |
| Induction | Induced at stage III of sporulation. |
| Sequence similarities | Belongs to the short-chain dehydrogenases/reductases (SDR) family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Sporulation |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | sporulation resulting in formation of a cellular spore Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular_function | glucose 1-dehydrogenase [NAD(P)] activity Inferred from electronic annotation. Source: EC nucleotide bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 261 | 261 | Glucose 1-dehydrogenase | PRO_0000054616 | |||||
Regions | |||||||||
| Nucleotide binding | 11 – 35 | 25 | NADP By similarity | ||||||
Sites | |||||||||
| Active site | 158 | 1 | Proton acceptor By similarity | ||||||
| Binding site | 145 | 1 | Substrate By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 148 – 150 | 3 | EVI → AF in AAA22463. Ref.1 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Characterization of the developmentally regulated Bacillus subtilis glucose dehydrogenase gene." Lampel K.A., Uratani B., Chaudhry G.R., Ramaley R.F., Rudikoff S. J. Bacteriol. 166:238-243(1986) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "The 25 degrees-36 degrees region of the Bacillus subtilis chromosome: determination of the sequence of a 146 kb segment and identification of 113 genes." Yamane K., Kumano M., Kurita K. Microbiology 142:3047-3056(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168. |
| [3] | "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. Danchin A.Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | M12276 Genomic DNA. Translation: AAA22463.1. D50453 Genomic DNA. Translation: BAA09024.1. AL009126 Genomic DNA. Translation: CAB12201.1. |
| PIR | D69629. |
| RefSeq | NP_388275.1. NC_000964.3. |
3D structure databases | |
| ProteinModelPortal | P12310. |
| SMR | P12310. Positions 1-261. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 224308.BSU03930. |
Proteomic databases | |
| PaxDb | P12310. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | CAB12201; CAB12201; BSU03930. |
| GeneID | 938261. |
| KEGG | bsu:BSU03930. |
| PATRIC | 18972360. VBIBacSub10457_0408. |
Organism-specific databases | |
| GenoList | BSU03930. [Micado] |
Phylogenomic databases | |
| eggNOG | COG1028. |
| KO | K00034. |
| OMA | IKLMTET. |
| ProtClustDB | PRK08936. |
Enzyme and pathway databases | |
| BioCyc | BSUB:BSU03930-MONOMER. |
| SABIO-RK | P12310. |
Family and domain databases | |
| Gene3D | 3.40.50.720. 1 hit. |
| InterPro | IPR002198. DH_sc/Rdtase_SDR. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. IPR020904. Sc_DH/Rdtase_CS. [Graphical view] |
| Pfam | PF00106. adh_short. 1 hit. [Graphical view] |
| PRINTS | PR00081. GDHRDH. PR00080. SDRFAMILY. |
| PROSITE | PS00061. ADH_SHORT. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | DHG_BACSU | ||||||||
| Accession | Primary (citable) accession number: P12310 Secondary accession number(s): P94430 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Bacillus subtilis Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList |
| SIMILARITY comments Index of protein domains and families |

Clusters with
