SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P12289

- TRPF_CAUCR

UniProt

P12289 - TRPF_CAUCR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
N-(5'-phosphoribosyl)anthranilate isomerase
Gene
trpF, CC_3545
Organism
Caulobacter crescentus (strain ATCC 19089 / CB15)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciCAULO:CC3545-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:CC_3545
OrganismiCaulobacter crescentus (strain ATCC 19089 / CB15)
Taxonomic identifieri190650 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
ProteomesiUP000001816: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 219219N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation
PRO_0000154351Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP12289.
SMRiP12289. Positions 9-215.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiDILQLHG.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

P12289-1 [UniParc]FASTAAdd to Basket

« Hide

MSISAHGAKI CGLSTPETVK AAFDGAAAFL GFVFFDKSPR NVAPEVAARL    50
VEPVRGRGVQ TVAVTVDPDD ALIDRLMATM RPDLIQVHGK ETPSRVREIA 100
ARAGVGVIKA FSVSSSADVD QAAAFDGVAQ HLMFDARPVE GSVLPGGTGA 150
RFDWGLLAGR RFSRPHFLAG GLDPWNVGEA IKTSGTPLVD VSSGVERGPG 200
LKDPALISAF LDAVKRAKD 219
Length:219
Mass (Da):22,902
Last modified:October 1, 1989 - v1
Checksum:i7DB9F36454E553DB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M19129 Genomic DNA. Translation: AAA23056.1.
AE005673 Genomic DNA. Translation: AAK25507.1.
PIRiB43664.
RefSeqiNP_422339.1. NC_002696.2.
WP_010921374.1. NC_002696.2.

Genome annotation databases

EnsemblBacteriaiAAK25507; AAK25507; CC_3545.
GeneIDi943242.
KEGGiccr:CC_3545.
PATRICi21304128. VBICauCre124313_3550.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M19129 Genomic DNA. Translation: AAA23056.1 .
AE005673 Genomic DNA. Translation: AAK25507.1 .
PIRi B43664.
RefSeqi NP_422339.1. NC_002696.2.
WP_010921374.1. NC_002696.2.

3D structure databases

ProteinModelPortali P12289.
SMRi P12289. Positions 9-215.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK25507 ; AAK25507 ; CC_3545 .
GeneIDi 943242.
KEGGi ccr:CC_3545.
PATRICi 21304128. VBICauCre124313_3550.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi DILQLHG.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci CAULO:CC3545-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structure of the Caulobacter crescentus trpFBA operon."
    Ross C.M., Winkler M.E.
    J. Bacteriol. 170:757-768(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 19089 / CB15.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19089 / CB15.

Entry informationi

Entry nameiTRPF_CAUCR
AccessioniPrimary (citable) accession number: P12289
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: October 1, 1989
Last modified: September 3, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi