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P12289 (TRPF_CAUCR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-(5'-phosphoribosyl)anthranilate isomerase

Short name=PRAI
EC=5.3.1.24
Gene names
Name:trpF
Ordered Locus Names:CC_3545
OrganismCaulobacter crescentus (strain ATCC 19089 / CB15) [Reference proteome] [HAMAP]
Taxonomic identifier190650 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter

Protein attributes

Sequence length219 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135

Sequence similarities

Belongs to the TrpF family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 219219N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135
PRO_0000154351

Sequences

Sequence LengthMass (Da)Tools
P12289 [UniParc].

Last modified October 1, 1989. Version 1.
Checksum: 7DB9F36454E553DB

FASTA21922,902
        10         20         30         40         50         60 
MSISAHGAKI CGLSTPETVK AAFDGAAAFL GFVFFDKSPR NVAPEVAARL VEPVRGRGVQ 

        70         80         90        100        110        120 
TVAVTVDPDD ALIDRLMATM RPDLIQVHGK ETPSRVREIA ARAGVGVIKA FSVSSSADVD 

       130        140        150        160        170        180 
QAAAFDGVAQ HLMFDARPVE GSVLPGGTGA RFDWGLLAGR RFSRPHFLAG GLDPWNVGEA 

       190        200        210 
IKTSGTPLVD VSSGVERGPG LKDPALISAF LDAVKRAKD 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M19129 Genomic DNA. Translation: AAA23056.1.
AE005673 Genomic DNA. Translation: AAK25507.1.
PIRB43664.
RefSeqNP_422339.1. NC_002696.2.

3D structure databases

ProteinModelPortalP12289.
SMRP12289. Positions 9-215.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK25507; AAK25507; CC_3545.
GeneID943242.
KEGGccr:CC_3545.
PATRIC21304128. VBICauCre124313_3550.

Phylogenomic databases

eggNOGCOG0135.
HOGENOMHOG000161598.
KOK01817.
OMAFVNASRC.
OrthoDBEOG6N94DF.
ProtClustDBPRK01222.

Enzyme and pathway databases

BioCycCAULO:CC3545-MONOMER.
UniPathwayUPA00035; UER00042.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00135. PRAI.
InterProIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRPF_CAUCR
AccessionPrimary (citable) accession number: P12289
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: October 1, 1989
Last modified: February 19, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways