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P12289

- TRPF_CAUCR

UniProt

P12289 - TRPF_CAUCR

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Caulobacter crescentus (strain ATCC 19089 / CB15)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 97 (01 Oct 2014)
      Sequence version 1 (01 Oct 1989)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

    Pathwayi

    GO - Molecular functioni

    1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciCAULO:CC3545-MONOMER.
    UniPathwayiUPA00035; UER00042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
    Short name:
    PRAI
    Gene namesi
    Name:trpF
    Ordered Locus Names:CC_3545
    OrganismiCaulobacter crescentus (strain ATCC 19089 / CB15)
    Taxonomic identifieri190650 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
    ProteomesiUP000001816: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 219219N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154351Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP12289.
    SMRiP12289. Positions 9-215.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpF family.Curated

    Phylogenomic databases

    eggNOGiCOG0135.
    HOGENOMiHOG000161598.
    KOiK01817.
    OMAiDILQLHG.
    OrthoDBiEOG6N94DF.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00135. PRAI.
    InterProiIPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00697. PRAI. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P12289-1 [UniParc]FASTAAdd to Basket

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    MSISAHGAKI CGLSTPETVK AAFDGAAAFL GFVFFDKSPR NVAPEVAARL    50
    VEPVRGRGVQ TVAVTVDPDD ALIDRLMATM RPDLIQVHGK ETPSRVREIA 100
    ARAGVGVIKA FSVSSSADVD QAAAFDGVAQ HLMFDARPVE GSVLPGGTGA 150
    RFDWGLLAGR RFSRPHFLAG GLDPWNVGEA IKTSGTPLVD VSSGVERGPG 200
    LKDPALISAF LDAVKRAKD 219
    Length:219
    Mass (Da):22,902
    Last modified:October 1, 1989 - v1
    Checksum:i7DB9F36454E553DB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M19129 Genomic DNA. Translation: AAA23056.1.
    AE005673 Genomic DNA. Translation: AAK25507.1.
    PIRiB43664.
    RefSeqiNP_422339.1. NC_002696.2.
    WP_010921374.1. NC_002696.2.

    Genome annotation databases

    EnsemblBacteriaiAAK25507; AAK25507; CC_3545.
    GeneIDi943242.
    KEGGiccr:CC_3545.
    PATRICi21304128. VBICauCre124313_3550.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M19129 Genomic DNA. Translation: AAA23056.1 .
    AE005673 Genomic DNA. Translation: AAK25507.1 .
    PIRi B43664.
    RefSeqi NP_422339.1. NC_002696.2.
    WP_010921374.1. NC_002696.2.

    3D structure databases

    ProteinModelPortali P12289.
    SMRi P12289. Positions 9-215.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK25507 ; AAK25507 ; CC_3545 .
    GeneIDi 943242.
    KEGGi ccr:CC_3545.
    PATRICi 21304128. VBICauCre124313_3550.

    Phylogenomic databases

    eggNOGi COG0135.
    HOGENOMi HOG000161598.
    KOi K01817.
    OMAi DILQLHG.
    OrthoDBi EOG6N94DF.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00042 .
    BioCyci CAULO:CC3545-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00135. PRAI.
    InterProi IPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00697. PRAI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Structure of the Caulobacter crescentus trpFBA operon."
      Ross C.M., Winkler M.E.
      J. Bacteriol. 170:757-768(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 19089 / CB15.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 19089 / CB15.

    Entry informationi

    Entry nameiTRPF_CAUCR
    AccessioniPrimary (citable) accession number: P12289
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1989
    Last sequence update: October 1, 1989
    Last modified: October 1, 2014
    This is version 97 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3