P12261 (EF1G_ARTSA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Elongation factor 1-gamma Short name=EF-1-gamma Alternative name(s): eEF-1B gamma
Organism	Artemia salina (Brine shrimp)
Taxonomic identifier	85549 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Crustacea › Branchiopoda › Anostraca › Artemiidae › Artemia

Protein attributes

Sequence length	430 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Probably plays a role in anchoring the complex to other cellular components.
Subunit structure	EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
Sequence similarities	Contains 1 EF-1-gamma C-terminal domain. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Elongation factor
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular component	eukaryotic translation elongation factor 1 complex Inferred from electronic annotation. Source: InterPro
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed
	Chain	2 – 430	429	Elongation factor 1-gamma		PRO_0000208822
Regions
	Domain	2 – 84	83	GST N-terminal
	Domain	85 – 213	129	GST C-terminal
	Domain	271 – 430	160	EF-1-gamma C-terminal

Sequences

	Sequence		Length	Mass (Da)
	P12261 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 2AEA4ED040B3B383	FASTA	430	49,309
	10 20 30 40 50 60 MVAGKLYTYP ENFRAFKALI AAQYSGAKLE IAKSFVFGET NKSDAFLKSF PLGKVPAFES 70 80 90 100 110 120 ADGHCIAESN AIAYYVANET LRGSSDLEKA QIIQWMTFAD TEILPASCTW VFPVLGIMQF 130 140 150 160 170 180 NKQATARAKE DIDKALQALD DHLLTRTYLV GERITLADIV VTCTLLHLYQ HVLDEAFRKS 190 200 210 220 230 240 YVNTNRWFIT LINQKQVKAV IGDFKLCEKA GEFDPKKYAE FQAAIGSGEK KKTEKAPKAV 250 260 270 280 290 300 KAKPEKKEVP KKEQEEPADA AEEALAAEPK SKDPFDEMPK GTFNMDDFKR FYSNNEETKS 310 320 330 340 350 360 IPYFWEKFDK ENYSIWYSEY KYQDELAKVY MSCNLITGMF QRIEKMRKQA FASVCVFGED 370 380 390 400 410 420 NDSSISGIWV WRGQDLAFKL SPDWQIDYES YDWKKLDPDA QETKDLVTQY FTWTGTDKQG 430 RKFNQGKIFK

References

[1]	"Primary structure of elongation factor 1 gamma from Artemia." Maessen G.D.F., Amons R., Zeelen J.P., Moeller W. FEBS Lett. 223:181-186(1987) [PubMed: 3666137] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M28020 mRNA. Translation: AAC83401.1.
3D structure databases
ProteinModelPortal	P12261.
SMR	P12261. Positions 271-430.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR012336. Thioredoxin-like_fold. IPR001662. Transl_elong_EF1_G_con. [Graphical view]
Gene3D	G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit. G3DSA:3.30.70.1010. Transl_elong_EF1_G_con. 1 hit.
Pfam	PF00647. EF1G. 1 hit. PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view]
SUPFAM	SSF47616. GST_C_like. 1 hit. SSF52833. Thiordxn-like_fd. 1 hit. SSF89942. Transl_elong_EF1_G_con. 1 hit.
PROSITE	PS50040. EF1G_C. 1 hit. PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EF1G_ARTSA

Accession

Primary (citable) accession number: P12261

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1989
Last sequence update:	January 23, 2007
Last modified:	September 21, 2011
This is version 70 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)